EP2121985A4 - Genetics variants associated with hiv disease restriction - Google Patents

Genetics variants associated with hiv disease restriction

Info

Publication number
EP2121985A4
EP2121985A4 EP08727164A EP08727164A EP2121985A4 EP 2121985 A4 EP2121985 A4 EP 2121985A4 EP 08727164 A EP08727164 A EP 08727164A EP 08727164 A EP08727164 A EP 08727164A EP 2121985 A4 EP2121985 A4 EP 2121985A4
Authority
EP
European Patent Office
Prior art keywords
hiv disease
variants associated
restriction
genetics
genetics variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08727164A
Other languages
German (de)
French (fr)
Other versions
EP2121985A2 (en
Inventor
David B Goldstein
Amalio Telenti
Jacques Fellay
Kevin V Shianna
Dongliang Ge
Barton F Haynes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Lausanne
Duke University
Original Assignee
Universite de Lausanne
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Lausanne, Duke University filed Critical Universite de Lausanne
Publication of EP2121985A2 publication Critical patent/EP2121985A2/en
Publication of EP2121985A4 publication Critical patent/EP2121985A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • AIDS & HIV (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP08727164A 2007-03-27 2008-03-27 Genetics variants associated with hiv disease restriction Withdrawn EP2121985A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90727107P 2007-03-27 2007-03-27
US92943207P 2007-06-27 2007-06-27
PCT/US2008/003964 WO2008118469A2 (en) 2007-03-27 2008-03-27 Genetics variants associated with hiv disease restriction

Publications (2)

Publication Number Publication Date
EP2121985A2 EP2121985A2 (en) 2009-11-25
EP2121985A4 true EP2121985A4 (en) 2011-01-05

Family

ID=39789200

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08727164A Withdrawn EP2121985A4 (en) 2007-03-27 2008-03-27 Genetics variants associated with hiv disease restriction

Country Status (5)

Country Link
EP (1) EP2121985A4 (en)
JP (1) JP2010522560A (en)
AU (1) AU2008231305A1 (en)
CA (1) CA2680834A1 (en)
WO (1) WO2008118469A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105316417B (en) * 2015-11-27 2018-11-30 北京泱深生物信息技术有限公司 The diagnosis and treatment target of ZNRD1 gene and its expression product as intracranial aneurysm
EP3555303B1 (en) * 2016-12-14 2022-12-21 Merck Sharp & Dohme Corp. Human genetic markers associated with response to treatments that target clostridium difficile toxin b

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130152A2 (en) * 2004-11-26 2006-12-07 Board Of Regents, University Of Texas System Methods and compositions for correlating ccl3l1/ccr5 genotypes with disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130152A2 (en) * 2004-11-26 2006-12-07 Board Of Regents, University Of Texas System Methods and compositions for correlating ccl3l1/ccr5 genotypes with disorders

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
HOGAN C M ET AL: "Host determinants in HIV infection and disease: Part 2: Genetic factors and implications for antiretroviral therapeutics", ANNALS OF INTERNAL MEDICINE, vol. 134, no. 10, 15 May 2001 (2001-05-15), NEW YORK, NY; US, pages 978 - 996, XP002276751, ISSN: 0003-4819 *
KIEPIELA PHOTINI ET AL: "Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.", NATURE, vol. 432, no. 7018, 9 December 2004 (2004-12-09), pages 769 - 774, XP002606951, ISSN: 1476-4687 *
MOORE C B ET AL: "Evidence of HIV-1 adaptation to HLA restricted immune responses at a population level", SCIENCE, vol. 296, 24 May 2002 (2002-05-24), AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, pages 1439 - 1443, XP002986696, ISSN: 0036-8075, DOI: 10.1126/SCIENCE.1069660 *
MUEHL THORSTEN ET AL: "MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys", JOURNAL OF IMMUNOLOGY, vol. 169, no. 6, 15 September 2002 (2002-09-15), pages 3438 - 3446, XP002606948, ISSN: 0022-1767 *
SHAO WENSHUO ET AL: "Cohort- and time-specific associations of CTLA4 genotypes with HIV-1 disease progression", AIDS (HAGERSTOWN), vol. 20, no. 12, August 2006 (2006-08-01), pages 1583 - 1590, XP002606947, ISSN: 0269-9370 *
TANG JIANMING ET AL: "Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1.", JOURNAL OF VIROLOGY, vol. 76, no. 16, August 2002 (2002-08-01), pages 8276 - 8284, XP002606952, ISSN: 0022-538X *
TELENTI AMALIO ET AL: "Genomics meets HIV-1.", NATURE REVIEWS. MICROBIOLOGY, vol. 4, no. 11, November 2006 (2006-11-01), pages 865 - 873, XP002606946, ISSN: 1740-1534 *
TRACHTENBERG ELIZABETH ET AL: "Advantage of rare HLA supertype in HIV disease progression.", NATURE MEDICINE, vol. 9, no. 7, July 2003 (2003-07-01), pages 928 - 935, XP002606950, ISSN: 1078-8956 *

Also Published As

Publication number Publication date
CA2680834A1 (en) 2008-10-02
WO2008118469A3 (en) 2008-12-24
AU2008231305A1 (en) 2008-10-02
WO2008118469A2 (en) 2008-10-02
EP2121985A2 (en) 2009-11-25
JP2010522560A (en) 2010-07-08

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20090928

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20101206

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20110504