EP2119438A4 - Bone metabolism ameliorating agent - Google Patents

Bone metabolism ameliorating agent

Info

Publication number
EP2119438A4
EP2119438A4 EP08722002A EP08722002A EP2119438A4 EP 2119438 A4 EP2119438 A4 EP 2119438A4 EP 08722002 A EP08722002 A EP 08722002A EP 08722002 A EP08722002 A EP 08722002A EP 2119438 A4 EP2119438 A4 EP 2119438A4
Authority
EP
European Patent Office
Prior art keywords
bone metabolism
ameliorating agent
metabolism ameliorating
agent
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP08722002A
Other languages
German (de)
French (fr)
Other versions
EP2119438B1 (en
EP2119438A1 (en
Inventor
Hidehiro Yamazaki
Toshihiro Ohki
Tomio Inaba
Naomi Sakaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advanced Renal Technologies Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of EP2119438A1 publication Critical patent/EP2119438A1/en
Publication of EP2119438A4 publication Critical patent/EP2119438A4/en
Application granted granted Critical
Publication of EP2119438B1 publication Critical patent/EP2119438B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3455—Substitution fluids
    • A61M1/3458—Substitution fluids having electrolytes not present in the dialysate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
EP08722002.6A 2007-03-14 2008-03-13 Bone metabolism ameliorating agent Active EP2119438B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007065660 2007-03-14
PCT/JP2008/054598 WO2008114679A1 (en) 2007-03-14 2008-03-13 Bone metabolism ameliorating agent

Publications (3)

Publication Number Publication Date
EP2119438A1 EP2119438A1 (en) 2009-11-18
EP2119438A4 true EP2119438A4 (en) 2010-08-25
EP2119438B1 EP2119438B1 (en) 2014-02-26

Family

ID=39765787

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08722002.6A Active EP2119438B1 (en) 2007-03-14 2008-03-13 Bone metabolism ameliorating agent

Country Status (7)

Country Link
US (1) US8715213B2 (en)
EP (1) EP2119438B1 (en)
JP (1) JP5667762B2 (en)
KR (1) KR101461436B1 (en)
CN (1) CN101631540A (en)
TW (1) TWI419683B (en)
WO (1) WO2008114679A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI419683B (en) * 2007-03-14 2013-12-21 Ajinomoto Kk Bone metabolism improving agent
EP2334292B1 (en) * 2008-10-17 2019-05-08 Fresenius Medical Care Holdings, Inc. Method of determining a phosphorus binder dosage for a dialysis patient
ES2677603T3 (en) 2010-06-23 2018-08-03 Gambro Lundia Ab Precursor Dialysis Composition
BR112012033038B1 (en) 2010-06-23 2019-10-08 Gambro Lundia Ab PRECURSING DIALYSIS COMPOSITION
KR102001689B1 (en) 2011-06-20 2019-07-18 감브로 룬디아 아베 Dialysis precursor composition
CA2836442C (en) 2011-06-20 2021-02-23 Gambro Lundia Ab Dialysis precursor composition
JP5282923B2 (en) * 2011-12-06 2013-09-04 富田製薬株式会社 Bicarbonate dialysate
ES2684193T3 (en) 2011-12-21 2018-10-01 Gambro Lundia Ab Precursor Dialysis Composition
PL2793903T3 (en) 2011-12-21 2018-12-31 Gambro Lundia Ab Dialysis precursor composition
SE536913C2 (en) 2012-03-08 2014-10-28 Gambro Lundia Ab Composition for dialysis
AU2013201546B2 (en) 2012-12-18 2014-10-23 Gambro Lundia Ab Dialysis composition

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1834652A1 (en) * 2005-01-07 2007-09-19 Ajinomoto Co., Inc. Dialysis preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9205983A (en) * 1991-05-06 1994-08-02 Procter & Gamble Combined calcium and vitamin D supplements
JP5204359B2 (en) 2001-09-28 2013-06-05 味の素株式会社 Dialysis agent and method for producing the same
JP2003339853A (en) * 2002-05-27 2003-12-02 Shimizu Pharmaceutical Co Ltd Stable dialysis agent
TWI419683B (en) * 2007-03-14 2013-12-21 Ajinomoto Kk Bone metabolism improving agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1834652A1 (en) * 2005-01-07 2007-09-19 Ajinomoto Co., Inc. Dialysis preparation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MALBERTI FABIO ET AL: "The choice of the dialysate calcium concentration in the management of patients on haemodialysis and haemodiafiltration.", NEPHROLOGY DIALYSIS TRANSPLANTATION, vol. 18, no. Supplement 7, August 2003 (2003-08-01), pages VII37 - VII40, XP009135589, ISSN: 0931-0509 *
SPASOVSKI GOCE ET AL: "Could various dialysate calcium concentration treatment improve adynamic bone disease", NEPHROLOGY DIALYSIS TRANSPLANTATION, vol. 21, no. Suppl. 4, July 2006 (2006-07-01), & 43RD ERA-EDTA CONGRESS; GLASGOW, UK; JULY 15 -18, 2006, pages 421, XP009135591, ISSN: 0931-0509 *

Also Published As

Publication number Publication date
KR101461436B1 (en) 2014-11-13
TWI419683B (en) 2013-12-21
WO2008114679A1 (en) 2008-09-25
US20100056974A1 (en) 2010-03-04
TW200901963A (en) 2009-01-16
CN101631540A (en) 2010-01-20
EP2119438B1 (en) 2014-02-26
EP2119438A1 (en) 2009-11-18
US8715213B2 (en) 2014-05-06
KR20100015576A (en) 2010-02-12
JPWO2008114679A1 (en) 2010-07-01
JP5667762B2 (en) 2015-02-12

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