EP2097749A4 - Assay for cardiac troponin autoantibodies - Google Patents
Assay for cardiac troponin autoantibodiesInfo
- Publication number
- EP2097749A4 EP2097749A4 EP07871173A EP07871173A EP2097749A4 EP 2097749 A4 EP2097749 A4 EP 2097749A4 EP 07871173 A EP07871173 A EP 07871173A EP 07871173 A EP07871173 A EP 07871173A EP 2097749 A4 EP2097749 A4 EP 2097749A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- assay
- cardiac troponin
- troponin autoantibodies
- autoantibodies
- cardiac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/588,073 US7776605B2 (en) | 2006-10-26 | 2006-10-26 | Assay for cardiac troponin autoantibodies |
PCT/US2007/081606 WO2008051761A2 (en) | 2006-10-26 | 2007-10-17 | Assay for cardiac troponin autoantibodies |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2097749A2 EP2097749A2 (en) | 2009-09-09 |
EP2097749A4 true EP2097749A4 (en) | 2009-12-30 |
Family
ID=39325249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07871173A Withdrawn EP2097749A4 (en) | 2006-10-26 | 2007-10-17 | Assay for cardiac troponin autoantibodies |
Country Status (6)
Country | Link |
---|---|
US (4) | US7776605B2 (en) |
EP (1) | EP2097749A4 (en) |
JP (1) | JP2010508515A (en) |
CA (1) | CA2666586A1 (en) |
MX (1) | MX2009004463A (en) |
WO (1) | WO2008051761A2 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070172888A1 (en) * | 2006-01-25 | 2007-07-26 | Klaus Hallermayer | Measuring troponin antibodies to assess cardiovascular risk |
US7776605B2 (en) * | 2006-10-26 | 2010-08-17 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
US20080305512A1 (en) * | 2006-10-26 | 2008-12-11 | Mattingly Phillip G | Assay for cardiac troponin autoantibodies |
WO2008051762A2 (en) * | 2006-10-26 | 2008-05-02 | Abbott Laboratories | Immunoassay of analytes in samples containing endogenous anti-analyte antibodies |
US8420330B2 (en) | 2011-07-15 | 2013-04-16 | Myra A. Lipes | Diagnosis and treatment of cardiac troponin 1 (cTn1) autoantibody-mediated heart disease |
US8278057B2 (en) | 2007-09-14 | 2012-10-02 | Nestec S.A. | Addressable antibody arrays and methods of use |
WO2009118185A1 (en) * | 2008-03-27 | 2009-10-01 | Universitätsklinikum Heidelberg | Peptides derived from cardial troponin i and their use as prognostic and diagnostic markers for heart failure |
US20090286329A1 (en) * | 2008-05-19 | 2009-11-19 | Abbott Laboratoires | Isolated human autoantibodies to natriuretic peptides and methods and kits for detecting human autoantibodies to natriuretic peptides |
US20090286256A1 (en) * | 2008-05-19 | 2009-11-19 | Abbott Laboratories | Isolated human autoantibodies to natriuretic peptides and methods and kits for detecting human autoantibodies to natriuretic peptides |
CA2754980A1 (en) * | 2009-03-18 | 2010-09-23 | Prometheus Laboratories Inc. | Addressable antibody arrays and methods of use |
US8652788B2 (en) * | 2009-12-02 | 2014-02-18 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
US8835120B2 (en) * | 2009-12-02 | 2014-09-16 | Abbott Laboratories | Assay for cardiac troponin-T (cTnT) |
US20110136141A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
EP2517015A1 (en) * | 2009-12-23 | 2012-10-31 | Koninklijke Philips Electronics N.V. | Analyte measurement apparatus and method |
EP2580593A4 (en) * | 2010-06-10 | 2014-04-16 | Myra Lipes | Diagnosis of myocardial autoimmunity in heart disease |
US20110306148A1 (en) | 2010-06-14 | 2011-12-15 | Siemens Healthcare Diagnostics Inc. | Composition for use as an assay reagent |
US20130121998A1 (en) * | 2010-06-16 | 2013-05-16 | Myra A. Lipes | Diagnosis of Myocardial Autoimmunity in Heart Disease |
WO2014097877A1 (en) * | 2012-12-19 | 2014-06-26 | コニカミノルタ株式会社 | Sensor chip and spfs immunofluorescence measurement system |
US10670611B2 (en) | 2014-09-26 | 2020-06-02 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
EP3634528B1 (en) | 2017-06-07 | 2023-06-07 | Shifamed Holdings, LLC | Intravascular fluid movement devices, systems, and methods of use |
EP3477300A1 (en) * | 2017-10-25 | 2019-05-01 | Euroimmun Medizinische Labordiagnostika AG | Cellulose-based immunoadsorber |
CN111556763B (en) | 2017-11-13 | 2023-09-01 | 施菲姆德控股有限责任公司 | Intravascular fluid movement device and system |
JP7410034B2 (en) | 2018-02-01 | 2024-01-09 | シファメド・ホールディングス・エルエルシー | Intravascular blood pump and methods of use and manufacture |
WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
EP4034192A4 (en) | 2019-09-25 | 2023-11-29 | Shifamed Holdings, LLC | Intravascular blood pump systems and methods of use and control thereof |
CN112526140A (en) * | 2020-11-16 | 2021-03-19 | 北京利德曼生化股份有限公司 | Magnetic particle chemiluminescence detection kit for determining content of hypersensitive troponin T |
Citations (1)
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WO2007085411A1 (en) * | 2006-01-25 | 2007-08-02 | Roche Diagnostics Gmbh | Anti-troponin antibodies and cardiovascular risk |
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US20070172888A1 (en) * | 2006-01-25 | 2007-07-26 | Klaus Hallermayer | Measuring troponin antibodies to assess cardiovascular risk |
US20080305512A1 (en) | 2006-10-26 | 2008-12-11 | Mattingly Phillip G | Assay for cardiac troponin autoantibodies |
WO2008051762A2 (en) | 2006-10-26 | 2008-05-02 | Abbott Laboratories | Immunoassay of analytes in samples containing endogenous anti-analyte antibodies |
US7776605B2 (en) | 2006-10-26 | 2010-08-17 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
-
2006
- 2006-10-26 US US11/588,073 patent/US7776605B2/en not_active Expired - Fee Related
-
2007
- 2007-10-17 EP EP07871173A patent/EP2097749A4/en not_active Withdrawn
- 2007-10-17 CA CA002666586A patent/CA2666586A1/en not_active Abandoned
- 2007-10-17 WO PCT/US2007/081606 patent/WO2008051761A2/en active Application Filing
- 2007-10-17 JP JP2009534772A patent/JP2010508515A/en active Pending
- 2007-10-17 MX MX2009004463A patent/MX2009004463A/en active IP Right Grant
-
2008
- 2008-08-28 US US12/200,213 patent/US20090017560A1/en not_active Abandoned
-
2010
- 2010-08-17 US US12/857,615 patent/US8173382B2/en not_active Expired - Fee Related
-
2012
- 2012-05-23 US US13/479,133 patent/US20120302458A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007085411A1 (en) * | 2006-01-25 | 2007-08-02 | Roche Diagnostics Gmbh | Anti-troponin antibodies and cardiovascular risk |
Non-Patent Citations (6)
Title |
---|
ADAMCZYK, M., ET AL: "Circulating Cardiac Troponin-I Autoantibodies in Human Plasma and Serum", CONTEMPORARY CHALLENGES IN AUTOIMMUNITY, vol. 1173, 2009, pages 67 - 74, XP002556066 * |
ERIKSSON S ET AL: "Autoantibodies against cardiac troponins", NEW ENGLAND JOURNAL OF MEDICINE, MASSACHUSETTS MEDICAL SOCIETY, BOSTON, MA, US, vol. 352, no. 1, 6 January 2005 (2005-01-06), pages 98 - 100, XP008060221, ISSN: 1533-4406 * |
ERIKSSON, S., ET AL: "Comparison of Cardiac Troponin I Immunoassays Variably Affected by Circulating Autoantibodies", CLINICAL CHEMISTRY, vol. 51, no. 5, 2005, pages 848 - 855, XP002556065 * |
ERIKSSON, S., ET AL: "Negative Interference in Cardiac Troponin I Immunoassays by Circulating Troponin Autoantibodies", CLINICAL CHEMISTRY, vol. 51, no. 5, 2005, pages 839 - 847 * |
See also references of WO2008051761A2 * |
SHMILOVICH ET AL: "Autoantibodies to cardiac troponin I in patients with idiopathic dilated and ischemic cardiomyopathy", INTERNATIONAL JOURNAL OF CARDIOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 117, no. 2, 2 August 2006 (2006-08-02), pages 198 - 203, XP022000067, ISSN: 0167-5273 * |
Also Published As
Publication number | Publication date |
---|---|
US20120302458A1 (en) | 2012-11-29 |
CA2666586A1 (en) | 2008-05-02 |
US20100311079A1 (en) | 2010-12-09 |
EP2097749A2 (en) | 2009-09-09 |
WO2008051761A2 (en) | 2008-05-02 |
JP2010508515A (en) | 2010-03-18 |
US8173382B2 (en) | 2012-05-08 |
US7776605B2 (en) | 2010-08-17 |
WO2008051761A3 (en) | 2008-11-13 |
US20090017560A1 (en) | 2009-01-15 |
MX2009004463A (en) | 2009-05-08 |
US20080102481A1 (en) | 2008-05-01 |
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Legal Events
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/68 20060101ALI20140113BHEP Ipc: G01N 33/543 20060101AFI20140113BHEP Ipc: G01N 33/564 20060101ALI20140113BHEP |
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