EP2094153A2 - Telematic system for using diagnostic reagent strips and method for acquiring calibration data - Google Patents
Telematic system for using diagnostic reagent strips and method for acquiring calibration dataInfo
- Publication number
- EP2094153A2 EP2094153A2 EP07866796A EP07866796A EP2094153A2 EP 2094153 A2 EP2094153 A2 EP 2094153A2 EP 07866796 A EP07866796 A EP 07866796A EP 07866796 A EP07866796 A EP 07866796A EP 2094153 A2 EP2094153 A2 EP 2094153A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- transceiving
- diagnostic
- central unit
- strips
- identification code
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
- A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1112—Global tracking of patients, e.g. by using GPS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
- A61B2505/07—Home care
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0266—Operational features for monitoring or limiting apparatus function
- A61B2560/0271—Operational features for monitoring or limiting apparatus function using a remote monitoring unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
- A61B2562/085—Sensors provided with means for identification, e.g. barcodes or memory chips combined with means for recording calibration data
Definitions
- the present invention relates to a telematic system for using diagnostic reagent strips and method for acquiring calibration data.
- the invention concerns a system permitting simplifying commercial distribution both of reactive diagnostic strips and calibration reference values necessary for their use, making at the same time more reliable diagnostic measurements that can be obtained.
- a first problem of reflectometers is a consequence of distribution of reactive strips, usually sold packaged.
- each reactive strip box is provided with a microchip, within which the above reference value is stored.
- Modern reflectometers can measure different medical parameters, among which glucose, cholesterol or triglycerides.
- glucose, cholesterol or triglycerides are used between the measurements of different parameters.
- This procedure is very cumbersome.
- the risk exists of loosing one of microchips between the different measurements of different parameters, thus making it unusable diagnostic strips corresponding to the lost microchip.
- logistic of said reactive strips is strongly conditioned by coupling of said microchips with the diagnostic strip packages, remarkably increasing managing costs.
- a further technical problem in the diagnostic field is that concerning timely collection of acquired measurement data.
- above- mentioned reflectometers can detect only one measurement each time.
- the user must write old measurements, so as to have a historical file of the same and permit to the doctor to have a suitable diagnostic situation.
- a telematic system for using diagnostic reagent strips for analysing tissues said reactive diagnostic strips being suitable to be read by an analysis device within which an set of calibration reference values has been stored, associated with said diagnostic strips, said analysis device being of the kind comprising a cavity receiving one or more of said diagnostic strips on which a tissue sample to be subjected to analyses has been placed by the user, said analysis device measuring one or more medical parameters; said system being characterised in that it comprises a central unit provided with data transceiving means; and one or more transceiving terminals, each one of said terminals being associated with a user and suitable to interface with said transceiving means of said central unit and comprising an analysis device; and in that each one of said reactive diagnostic strips has an associated reference code; and in that set of calibration reference values associated with said diagnostic strips, and with relevant identification code, is stored within said central unit; so that said user transmits said identification code to said central unit, by corresponding transceiving terminal, before using the diagnostic strip identified by the same and, then, said
- said reactive diagnostic strips are contained within packages, each package being indicated by an identification code valid for diagnostic strips contained therein; said central unit sending said calibration reference value set of diagnostic measurements that can be obtained with reactive diagnostic strips contained within the corresponding package to said transceiving terminal.
- said medical parameters can comprise glucose and/or cholesterol and/or triglycerides.
- connection channel between said central units and said transceiving terminals can be of the phone type, and particularly of the GSM and/or GPRS and/or UMTS type.
- said central unit can be connected with one or more users by the Internet.
- said users comprise doctors, diagnostic centres, analyses laboratory, statistic centres, research centres, sanitary operators.
- said central unit can detect possible exceeding of one or more pre-set thresholds by the measurements of said one or more parameters sending an aid message to at least one of said users.
- said analysis device can be integrated within the transceiving terminal.
- said transceiving terminals can comprise a plurality of dedicated controls for controlling said analysis device.
- said transceiving message can comprise a sliding panel, said sliding panel permitting access to said cavity of said at least a diagnostic strip.
- said cavity can be placed under said transceiving terminal.
- said analysis device can be integrated within a module, on the surface of which said cavity is obtained, said module being removably coupled with said transceiving terminal and suitable to permit housing a supply battery of said transceiving terminal.
- said module can permit operative interfacing of said analysis device with said transceiving terminal.
- said analysis device can be independent from said transceiving terminal and can be interfaced with the same.
- said analysis device can be a reflectometer.
- said transceiving terminals can comprise cellular phones.
- said transceiving terminals can comprise an RFID (Radio Frequency Identification Device) reader, and in that an RFID tag is associated on said diagnostic strips, so that approaching said RFID tag to said RFID, said RFID reader acquires said stored identification code.
- RFID Radio Frequency Identification Device
- each RFID can be associated with a diagnostic strip package.
- said transceiving terminals can comprise a memory, a GSM/GPRS modem and a GPS receiver module, said GPS receiver being suitable to permit localisation of the corresponding user, transceiving terminal sending data about position of user corresponding to said central unit in case measurement of one analyse has a value lower or higher than set thresholds.
- said system can comprise a processing unit connected with said central unit, suitable transferring to said central unit the calibration reference value set corresponding to the identification codes of diagnostic strips or of packages of diagnostic strips put on the market.
- said diagnostic strips comprise a hydrophilic support, on which a reference hole is realised, and a membrane on which said tissue sample to be subjected to analyses can be placed, said tissue sliding by capillarity within a channel through which it reaches said analysis device.
- said method can comprise the following step, before the above step (a):
- said transceiving terminals can comprise each one an alpha-numeric keyboard, and acquisition of identification code of reactive diagnostic strips during said step (a) occurs by key-stroking of the same by said keyboard.
- each identification code can correspond to a package containing a plurality of reactive diagnostic strips.
- step (a) acquisition of identification code of reactive diagnostic strips during said step (a) occurs by reading of the same code by said RFID reader approaching the RFID tag identifying the reactive diagnostic strips.
- every RFID tag containing an identification code can be applied to a package containing a plurality of reactive diagnostic strips.
- said transmission steps (b) and (c) and said reception step (d) can be realised by sending SMSs (Short Message System).
- said transmission steps (b) and (c) and said reception step (d) can be realised by GPRS data transmission.
- said transceiving terminal after said step (d), can store said set of calibration reference data within said memory unit.
- figure 1 shows a block diagram of the telematic system for using diagnostic reagent strips according to the invention
- figure 2a shows a front view of a first embodiment of a transceiving terminal to be used in the system according to figure 1
- figure 2b shows a lateral view of transceiving terminal according to figure 2a
- figure 2c shows a module for housing an analysis device
- figure 2d shows module of figure 2c coupled with a transceiving terminal to be used in the system of figure 1
- figure 3a shows a front view of a second embodiment of a transceiving terminal to be used in the system according to figure 1
- figure 3b shows a lateral view of transceiving terminal according to figure 3a
- figure 4 shows a
- Said system comprises a processing and control processing unit 2 provided with transceiving means (not shown in the figure) permitting its connection, by a transceiving channel 3, with a plurality of transceiving terminals 4' 4 n suitable to transmission and reception of data through said channel 3.
- transceiving terminals 4' 4 n are cellular phones.
- Transceiving channel 3 can be of every kind.
- said transceiving channel 3 is a cellular phone channel, e.g. GSM, GPRS, UMTS channel.
- Central unit 2 is connected to the Internet 5 through which a plurality of users 6', ... , 6 n , such as doctors, diagnostic centres, analyses laboratory, statistic centres, search departments, different sanitary operators, can access to information contained within said central unit 2.
- users 6', ... , 6 n such as doctors, diagnostic centres, analyses laboratory, statistic centres, search departments, different sanitary operators, can access to information contained within said central unit 2.
- Transceiving terminals 4, ..., 4 n comprise each an analysis device, particularly a reflectometer. By said device it is possible carrying out analyses of tissues, such as plasma, containing glucose, cholesterol, triglycerides and like.
- Analyses is carried out by introduction of reactive diagnostic strips within a suitable cavity (not shown in the present figure), obtained in said analysis device, on said strips being beforehand deposited a droplet of blood or tissue to be subjected to analyses. Then, said device carries out an analyses making a processing of detections made by an set of calibration reference data, that must be available at the device before measurement.
- each diagnostic strip or each package of strips of the same batch is provided with an identification number or code to be sent beforehand to the central unit 2.
- Identification code can be sent in two different ways:
- User cellular phone 4 must be configured for sending data by GPRS channel, introducing parameters necessary to connection, such as APN of telephone provider of SIM employed, Internet provider (IP) of server receiving data and number of server cellular phone (prepared to receive SMS in case no GPRS covering exists).
- APN of telephone provider of SIM employed
- IP Internet provider
- system 1 also permits making a plurality of telemedicine services. Among them it is possible mentioning:
- FIGS. 2a and 2b show a first embodiment of a transceiving terminal 4, where analysis device or riflectometer is integrated in a cellular phone, having a cavity 7, that remains visible after opening of a sliding door 41 , and in which it is possible placing an analyses diagnostic strip 8.
- area 8' is present at the top of diagnostic strip 8, where it is possible placing tissue sample (e.g. blood) to be analysed.
- tissue sample e.g. blood
- Cellular phone 4 provides a plurality of special keys 9 with respect to standard phone apparatuses, for an easy managing of analysis device functions. Particularly, for every parameter that can be detected we have a different kind of reactive strips. On the basis of the parameter to be detected (glucose, cholesterol, triglycerides) it is necessary key-stroking corresponding key. Thus, device is ready to detect the chosen parameter.
- Figures 2c and 2d show a further embodiment of a transceiving terminal 4 wherein analysis device is integrated in a module 42, that can be removably coupled with the same terminal.
- Transceiving terminal 4 supply battery 43 is housed within said module 42.
- Figures 3a and 3b show a first embodiment of a transceiving terminal 4, wherein a diagnostic strip 8 is introduced within cavity T from below.
- Figure 4 shows a block diagram of a cellular phone operating as transceiving terminal 4, wherein it is observed display 10, a
- GSM/GPRS modem 11 an alpha-numeric keyboard 12, a logic processing unit 13, a memory unit 14, a control module 15 and a GPS receiving module (16).
- Cellular phone 4 further provides additional keys 9, for quick control of functions of transferring identification code and reception of set of calibration reference data, analysis device 17, in this case a reflectometer, a possible RFID reader 18, and a plurality of control modules 19', 19", 19"', for controlling set of calibration reference data, keys and localisation functions, respectively, that will be described in the following.
- Figure 5 shows transceiving terminal 4, wherein starting configuration is carried out. Particularly: • a configuration procedure is set by said special keys 9;
- Figure 6 shows block diagram representing transceiving terminal during procedure of sending identification code and acquisition of set of calibration reference data. Particularly,:
- • key-stroked identification code can be controlled on display 10; • key-stroked code is transmitted by special keys 9 to the central unit 2, through GPRS/GSM modem, by a remote connection with the Internet; • central unit 2 is connected with diagnostic strip 8 manufacturer by its own processing unit or server 20. This transfers set of calibration reference data corresponding to identification codes of diagnostic strip 8 packages put on the market;
- central unit 2 sends set of calibration reference data to the transceiving terminal 4.
- Transceiving terminal 4 stores said data within memory 14.
- FIG. 7 shows a block diagram wherein transceiving terminal 4 is employed for carrying out a diagnostic measurement and for sending the same to a processing and control central unit 2 of the same. Particularly:
- diagnostic strip 8 is introduced within the cavity 7 or within hole 11 ;
- logic processing unit 13 detects from memory 14: (a) set of calibration reference data necessary for processing data detected from tissue sample on diagnostic strip 8 by reflectometer 17; and (b) server IP and APN of telephone provider and cellular phone number;
- logic processing unit 13 carries out calculation for obtaining measurement of selected diagnostic parameter
- transceiving terminal 4 is provided with an RFID reader 18 and RFID tag is provided on each diagnostic strip 8 package.
- procedure for sending identification code occurs as follows: • RFID reader 18 is activated by special keys 9;
- RFID reader 18 automatically acquires identification code stored within RFID tag
- GSM/GPRS modem 11 transmits identification code of package 21 detected by central unit 2, sending the set of calibration reference data to the transceiving terminal 4, which is stored within memory 14.
- central unit 2 is connected to processing unit 20 of diagnostic strip 8 manufacturer.
- RFID tag is preferably of the passive kind, so as to be economic, not being necessary active elements, such as batteries.
- system 1 autonomously and automatically makes all calibration operations. This permits carrying out this delicate operations in a simplified way, being it only necessary approaching reactive strip 8 package 21 to the transceiving terminal 4. This is particularly suitable for elderly persons, generally not prone to use and follow complicated telematic procedures.
- transceiving terminal 4 comprises a GPS receiving module 16, permitting detecting the user geographic position. Said transceiving terminal 4 can sand by said GPS receiving module 16 data concerning user position to said central unit 2 in case, for example, analyses measurement has a lower or higher value than a set threshold.
- Reactive diagnostic strips 8 can be of any kind. A preferred embodiment is shown in figures 9, 10a and 10b.
- Strips 8 shown have a hydrophilic support 22, on which a reference hole 23 is obtained, and a membrane 24, on which tissue sample (e.g. blood) can be placed. Tissue flows by capillarity within channel 25, by which it reaches reflectometer 17 for analysis.
- tissue sample e.g. blood
- Main advantages of the present invention are mainly a consequence of unifying the operation of two devices, such as cellular phone and reflectometer, or in vitro diagnostic device.
- An advantage of the present invention is that of easing remote monitoring of patients and at the same time optimising handling of reactive strips.
- a further advantage of the invention is that of ensuring from remote position perfect operation of reflectometer and realising tele- assistance services on a single device and ensuring diffusion of prevention by self-diagnosis and increase of use of diagnosis devices.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Business, Economics & Management (AREA)
- General Business, Economics & Management (AREA)
- Optics & Photonics (AREA)
- Radar, Positioning & Navigation (AREA)
- Physiology (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Computer Networks & Wireless Communication (AREA)
- Emergency Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000672A ITRM20060672A1 (en) | 2006-12-13 | 2006-12-13 | TELEMATIC SYSTEM FOR THE USE OF REACTIVE DIAGNOSTIC STRIPS AND METHOD OF ACQUISITION CALIBRATION DATA. |
PCT/IT2007/000864 WO2008072275A2 (en) | 2006-12-13 | 2007-12-11 | Telematic system for using diagnostic reagent strips and method for acquiring calibration data |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2094153A2 true EP2094153A2 (en) | 2009-09-02 |
Family
ID=39473432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07866796A Withdrawn EP2094153A2 (en) | 2006-12-13 | 2007-12-11 | Telematic system for using diagnostic reagent strips and method for acquiring calibration data |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2094153A2 (en) |
IT (1) | ITRM20060672A1 (en) |
WO (1) | WO2008072275A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10991185B1 (en) | 2020-07-20 | 2021-04-27 | Abbott Laboratories | Digital pass verification systems and methods |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITRM20080528A1 (en) * | 2008-10-06 | 2010-04-07 | Biochemical System Internat S R L | READING SYSTEM OF REACTIVE DIAGNOSTIC STRIPS AND ITS TELE-MEDICAL ASSISTANCE SYSTEM. |
US8394246B2 (en) | 2009-02-23 | 2013-03-12 | Roche Diagnostics Operations, Inc. | System and method for the electrochemical measurement of an analyte employing a remote sensor |
US20100234708A1 (en) * | 2009-03-16 | 2010-09-16 | Harvey Buck | Wirelessly configurable medical device for a broadcast network system |
KR20100109383A (en) * | 2009-03-30 | 2010-10-08 | 삼성전자주식회사 | Internet phone apparatus including biological analysis device, and a remote medical-service method using the same |
ITRM20130125A1 (en) * | 2013-03-01 | 2014-09-02 | Biochemical Systems Internat S Rl | DIAGNOSTIC SYSTEM FOR MEASURING THE GLICEMIA USABLE WITH PORTABLE ELECTRONIC DEVICES |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI107080B (en) * | 1997-10-27 | 2001-05-31 | Nokia Mobile Phones Ltd | measuring device |
US6748250B1 (en) * | 2001-04-27 | 2004-06-08 | Medoptix, Inc. | Method and system of monitoring a patient |
US7582262B2 (en) * | 2004-06-18 | 2009-09-01 | Roche Diagnostics Operations, Inc. | Dispenser for flattened articles |
-
2006
- 2006-12-13 IT IT000672A patent/ITRM20060672A1/en unknown
-
2007
- 2007-12-11 WO PCT/IT2007/000864 patent/WO2008072275A2/en active Application Filing
- 2007-12-11 EP EP07866796A patent/EP2094153A2/en not_active Withdrawn
Non-Patent Citations (1)
Title |
---|
See references of WO2008072275A2 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10991185B1 (en) | 2020-07-20 | 2021-04-27 | Abbott Laboratories | Digital pass verification systems and methods |
US10991190B1 (en) | 2020-07-20 | 2021-04-27 | Abbott Laboratories | Digital pass verification systems and methods |
US11514737B2 (en) | 2020-07-20 | 2022-11-29 | Abbott Laboratories | Digital pass verification systems and methods |
US11514738B2 (en) | 2020-07-20 | 2022-11-29 | Abbott Laboratories | Digital pass verification systems and methods |
US11574514B2 (en) | 2020-07-20 | 2023-02-07 | Abbott Laboratories | Digital pass verification systems and methods |
Also Published As
Publication number | Publication date |
---|---|
WO2008072275A2 (en) | 2008-06-19 |
WO2008072275A3 (en) | 2008-08-07 |
ITRM20060672A1 (en) | 2008-06-14 |
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