EP2068877A4 - Verbindungen und verfahren zur modulierung von angiogenese - Google Patents
Verbindungen und verfahren zur modulierung von angiogeneseInfo
- Publication number
- EP2068877A4 EP2068877A4 EP07840438A EP07840438A EP2068877A4 EP 2068877 A4 EP2068877 A4 EP 2068877A4 EP 07840438 A EP07840438 A EP 07840438A EP 07840438 A EP07840438 A EP 07840438A EP 2068877 A4 EP2068877 A4 EP 2068877A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compounds
- methods
- modulating angiogenesis
- angiogenesis
- modulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83199206P | 2006-07-19 | 2006-07-19 | |
PCT/US2007/073877 WO2008011513A2 (en) | 2006-07-19 | 2007-07-19 | Compounds and methods of modulating angiogenesis |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2068877A2 EP2068877A2 (de) | 2009-06-17 |
EP2068877A4 true EP2068877A4 (de) | 2011-09-21 |
Family
ID=38957616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07840438A Withdrawn EP2068877A4 (de) | 2006-07-19 | 2007-07-19 | Verbindungen und verfahren zur modulierung von angiogenese |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2068877A4 (de) |
WO (1) | WO2008011513A2 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5566293B2 (ja) * | 2007-10-04 | 2014-08-06 | バイオノミックス リミテッド | 内皮細胞マーカーおよびその使用 |
WO2011116026A2 (en) * | 2010-03-15 | 2011-09-22 | The Board Of Trustees Of The University Of Illinois | Inhibitors of beta integrin-g protein alpha subunit binding interactions |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998016241A1 (en) * | 1996-10-15 | 1998-04-23 | Vanderbilt University | Method of disrupting cellular adhesion |
WO1998022500A2 (en) * | 1996-11-21 | 1998-05-28 | Cor Therapeutics, Inc. | Modulation of interactions between myosin and integrins |
WO2001079144A2 (en) * | 2000-04-14 | 2001-10-25 | Cor Therapeutics, Inc. | Fyn kinase as a target for modulation of integrin mediated signal transduction |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4244946A (en) | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
US6750044B1 (en) | 1996-10-17 | 2004-06-15 | Genentech, Inc. | Variants of vascular endothelial cell growth factor having antagonistic properties, nucleic acids encoding the same and host cells comprising those nucleic acids |
EP1787999B1 (de) | 1997-04-07 | 2010-08-04 | Genentech, Inc. | Anti-VEGF Antikörper |
WO2001094312A2 (en) * | 2000-06-02 | 2001-12-13 | Sugen, Inc. | Indolinone derivatives as protein kinase/phosphatase inhibitors |
US6958340B2 (en) * | 2001-08-01 | 2005-10-25 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
-
2007
- 2007-07-19 WO PCT/US2007/073877 patent/WO2008011513A2/en active Application Filing
- 2007-07-19 EP EP07840438A patent/EP2068877A4/de not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998016241A1 (en) * | 1996-10-15 | 1998-04-23 | Vanderbilt University | Method of disrupting cellular adhesion |
WO1998022500A2 (en) * | 1996-11-21 | 1998-05-28 | Cor Therapeutics, Inc. | Modulation of interactions between myosin and integrins |
WO2001079144A2 (en) * | 2000-04-14 | 2001-10-25 | Cor Therapeutics, Inc. | Fyn kinase as a target for modulation of integrin mediated signal transduction |
Non-Patent Citations (4)
Title |
---|
FRIEDLANDER MARTIN ET AL: "Involvement of integrins, alpha-v-beta-3 and alpha-v-beta-5 in ocular neovascular diseases", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, no. 18, 1996, pages 9764 - 9769, XP000986063, ISSN: 0027-8424 * |
MAHABALESHWAR GANAPATI H ET AL: "Beta 3 integrin phosphorylation and VEGF signaling", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 106, no. 11, Part 1, 1 November 2005 (2005-11-01), pages 159A, XP009151001, ISSN: 0006-4971 * |
See also references of WO2008011513A2 * |
SOLDI RAFFAELLA ET AL: "Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, vol. 18, no. 4, 15 February 1999 (1999-02-15), pages 882 - 892, XP002656146, ISSN: 0261-4189 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008011513B1 (en) | 2008-10-16 |
EP2068877A2 (de) | 2009-06-17 |
WO2008011513A2 (en) | 2008-01-24 |
WO2008011513A3 (en) | 2008-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090219 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20110823 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 38/04 20060101AFI20110812BHEP Ipc: A61P 35/00 20060101ALI20110812BHEP Ipc: A61K 38/17 20060101ALI20110812BHEP Ipc: A61K 31/47 20060101ALI20110812BHEP Ipc: C07D 215/16 20060101ALI20110812BHEP Ipc: A61K 38/08 20060101ALI20110812BHEP Ipc: A61P 27/02 20060101ALI20110812BHEP Ipc: C07D 215/20 20060101ALI20110812BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20171113 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20180807 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20181218 |