EP2068709A4 - Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri - Google Patents

Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri

Info

Publication number
EP2068709A4
EP2068709A4 EP07839139A EP07839139A EP2068709A4 EP 2068709 A4 EP2068709 A4 EP 2068709A4 EP 07839139 A EP07839139 A EP 07839139A EP 07839139 A EP07839139 A EP 07839139A EP 2068709 A4 EP2068709 A4 EP 2068709A4
Authority
EP
European Patent Office
Prior art keywords
hyperpolarized
mri
systems
methods
gas transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07839139A
Other languages
German (de)
French (fr)
Other versions
EP2068709A1 (en
Inventor
Bastiaan Driehuys
Gary Price Cofer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of EP2068709A1 publication Critical patent/EP2068709A1/en
Publication of EP2068709A4 publication Critical patent/EP2068709A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1075—Measuring physical dimensions, e.g. size of the entire body or parts thereof for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/34046—Volume type coils, e.g. bird-cage coils; Quadrature bird-cage coils; Circularly polarised coils
    • G01R33/34076—Birdcage coils
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4816—NMR imaging of samples with ultrashort relaxation times such as solid samples, e.g. MRI using ultrashort TE [UTE], single point imaging, constant time imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4887—Locating particular structures in or on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Signal Processing (AREA)
  • Pulmonology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Optics & Photonics (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
EP07839139A 2006-10-03 2007-10-02 Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri Ceased EP2068709A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82798306P 2006-10-03 2006-10-03
PCT/US2007/021155 WO2008042370A1 (en) 2006-10-03 2007-10-02 Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri

Publications (2)

Publication Number Publication Date
EP2068709A1 EP2068709A1 (en) 2009-06-17
EP2068709A4 true EP2068709A4 (en) 2010-03-31

Family

ID=39268769

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07839139A Ceased EP2068709A4 (en) 2006-10-03 2007-10-02 Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri

Country Status (11)

Country Link
US (5) US20100027864A1 (en)
EP (1) EP2068709A4 (en)
JP (1) JP2010505516A (en)
KR (1) KR20090086396A (en)
CN (1) CN101553168A (en)
AU (1) AU2007305310B2 (en)
BR (1) BRPI0718198A2 (en)
CA (3) CA3152286C (en)
NZ (1) NZ575856A (en)
RU (1) RU2452372C2 (en)
WO (1) WO2008042370A1 (en)

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RU2452372C2 (en) * 2006-10-03 2012-06-10 Дьюк Юниверсити SYSTEMS AND METHODS OF ESTIMATING GASA TRANSFER IN LUNGS WITH APPLICATION OF MRT WITH HYPERPOLARISED 129Xe
US20100280358A1 (en) * 2009-05-01 2010-11-04 University Of Virginia Patent Foundation Single breath-hold system and method for detection and assessment of multi-organ physiologic, morphologic and structural changes
JP2013006019A (en) * 2011-05-23 2013-01-10 Toshiba Corp Medical image diagnostic apparatus, image processor and ultrasonic diagnostic apparatus
US10191126B2 (en) * 2013-04-04 2019-01-29 Regents Of The University Of Minnesota Systems and methods for spatial gradient-based electrical property properties tomography using magnetic resonance imaging
US11428761B2 (en) 2014-06-04 2022-08-30 Koninklijke Philips N.V. Patient proximity-modulated specific absorption rate
KR20190040929A (en) * 2016-01-11 2019-04-19 엘레멘탈 사이언티픽 레이저스 엘엘씨 Simultaneous pattern during sample processing - scan layout
JP6686733B2 (en) * 2016-06-23 2020-04-22 コニカミノルタ株式会社 Dynamic analysis system
RU2653994C1 (en) * 2017-05-12 2018-05-15 Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения России (ФГБУ "РКНПК" МЗ РФ) Method for evaluation of the volume of pulmonary perfusion disorders
KR101949486B1 (en) * 2017-05-29 2019-02-18 성균관대학교산학협력단 Device and method for generating magnetic resonance imaging
KR101949491B1 (en) * 2017-05-29 2019-02-18 성균관대학교산학협력단 Device and method for generating magnetic resonance imaging
US10677874B2 (en) * 2018-02-20 2020-06-09 Wisconsin Alumni Research Foundation System and method for control of hyperpolarized gas-phase contamination in spectroscopic magnetic resonance imaging
US11944424B2 (en) * 2018-05-18 2024-04-02 Duke University Dynamic 129Xe gas exchange spectroscopy
US11531851B2 (en) * 2019-02-05 2022-12-20 The Regents Of The University Of Michigan Sequential minimal optimization algorithm for learning using partially available privileged information

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US20010000727A1 (en) * 1998-03-18 2001-05-03 Bastiaan Driehuys Methods for imaging pulmonary and cardiac vasculature and evaluating blood flow using dissolved polarized 129 Xe
EP1286171A2 (en) * 1998-03-18 2003-02-26 Medi-Physics, Inc. MR evaluation of vascular perfusion by means of hyperpolarized 129Xe
US6211677B1 (en) * 1998-05-08 2001-04-03 Picker International, Inc. Lung coil for imaging hyper-polarized gas in an MRI scanner
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See also references of WO2008042370A1 *

Also Published As

Publication number Publication date
CA3065182C (en) 2022-05-17
RU2009116459A (en) 2010-11-10
US10895620B2 (en) 2021-01-19
US20190187231A1 (en) 2019-06-20
WO2008042370A1 (en) 2008-04-10
US20080089846A1 (en) 2008-04-17
NZ575856A (en) 2011-06-30
US9625550B2 (en) 2017-04-18
CA2666043A1 (en) 2008-04-10
CA3152286A1 (en) 2008-04-10
EP2068709A1 (en) 2009-06-17
US8911709B2 (en) 2014-12-16
RU2452372C2 (en) 2012-06-10
CA3152286C (en) 2024-05-28
CA3065182A1 (en) 2008-04-10
US20150130459A1 (en) 2015-05-14
US20100027864A1 (en) 2010-02-04
KR20090086396A (en) 2009-08-12
AU2007305310A1 (en) 2008-04-10
AU2007305310B2 (en) 2013-01-17
US20170176559A1 (en) 2017-06-22
CN101553168A (en) 2009-10-07
US10261151B2 (en) 2019-04-16
BRPI0718198A2 (en) 2013-11-12
JP2010505516A (en) 2010-02-25
CA2666043C (en) 2020-02-25

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