EP2064644A4 - Verwendung einer impedanz-basierten zellprofilierung zur klassifikation von zellenreaktionsprofilen bei der zugabe biologisch aktiver wirkstoffe - Google Patents
Verwendung einer impedanz-basierten zellprofilierung zur klassifikation von zellenreaktionsprofilen bei der zugabe biologisch aktiver wirkstoffeInfo
- Publication number
- EP2064644A4 EP2064644A4 EP07838594A EP07838594A EP2064644A4 EP 2064644 A4 EP2064644 A4 EP 2064644A4 EP 07838594 A EP07838594 A EP 07838594A EP 07838594 A EP07838594 A EP 07838594A EP 2064644 A4 EP2064644 A4 EP 2064644A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- impedance
- exposure
- biologically active
- active agents
- cellular response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Bioinformatics & Computational Biology (AREA)
- Software Systems (AREA)
- Evolutionary Biology (AREA)
- Public Health (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Computation (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Bioethics (AREA)
- Artificial Intelligence (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84606706P | 2006-09-20 | 2006-09-20 | |
PCT/US2007/020418 WO2008036375A2 (en) | 2006-09-20 | 2007-09-20 | Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2064644A2 EP2064644A2 (de) | 2009-06-03 |
EP2064644A4 true EP2064644A4 (de) | 2010-12-29 |
Family
ID=39201101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07838594A Withdrawn EP2064644A4 (de) | 2006-09-20 | 2007-09-20 | Verwendung einer impedanz-basierten zellprofilierung zur klassifikation von zellenreaktionsprofilen bei der zugabe biologisch aktiver wirkstoffe |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2064644A4 (de) |
WO (1) | WO2008036375A2 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120015846A1 (en) * | 2010-07-16 | 2012-01-19 | Ye Fang | Label-free Cellular Pharmacology For Drug Antitarget Assessment |
GB201522323D0 (en) * | 2015-12-17 | 2016-02-03 | Vrije Universiteit Brussel And Katholieke Universiteit Leuven | Systems and methods for conducting electrochemical impedance spectroscopy |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6377057B1 (en) * | 1999-02-18 | 2002-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Classification of biological agents according to the spectral density signature of evoked changes in cellular electric potential |
WO2005005979A1 (en) * | 2003-07-14 | 2005-01-20 | Mds Inc. , Doing Business As Mds Sciex | Label-free method for classification and characterization of cellular events |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981268A (en) * | 1997-05-30 | 1999-11-09 | Board Of Trustees, Leland Stanford, Jr. University | Hybrid biosensors |
US8263375B2 (en) * | 2002-12-20 | 2012-09-11 | Acea Biosciences | Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology |
CA2556219A1 (en) * | 2004-02-09 | 2005-08-25 | Acea Biosciences, Inc. | Methods for assaying cells using cell-substrate impedance monitoring |
-
2007
- 2007-09-20 WO PCT/US2007/020418 patent/WO2008036375A2/en active Application Filing
- 2007-09-20 EP EP07838594A patent/EP2064644A4/de not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6377057B1 (en) * | 1999-02-18 | 2002-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Classification of biological agents according to the spectral density signature of evoked changes in cellular electric potential |
WO2005005979A1 (en) * | 2003-07-14 | 2005-01-20 | Mds Inc. , Doing Business As Mds Sciex | Label-free method for classification and characterization of cellular events |
Non-Patent Citations (1)
Title |
---|
SLAUGHTER G E ET AL: "Artificial Neural Network for Temporal Impedance Recognition of Neurotoxins", INTERNATIONAL JOINT CONFERENCE ON NEURAL NETWORKS, 2006. IJCNN '06, PISCATAWAY, NJ : IEEE OPERATIONS CENTER, PISCATAWAY, NJ, USA LNKD- DOI:10.1109/IJCNN.2006.1716357, 16 July 2006 (2006-07-16), pages 2001 - 2008, XP010948436, ISBN: 978-0-7803-9490-2 * |
Also Published As
Publication number | Publication date |
---|---|
EP2064644A2 (de) | 2009-06-03 |
WO2008036375A2 (en) | 2008-03-27 |
WO2008036375A3 (en) | 2008-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090331 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: ACEA BIOSCIENCES, INC. |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20101130 |
|
17Q | First examination report despatched |
Effective date: 20120220 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Effective date: 20160226 |