EP2057190A4 - Monoklonale anti-interferon-alpha-antikörper und verwendungsverfahren dafür - Google Patents
Monoklonale anti-interferon-alpha-antikörper und verwendungsverfahren dafürInfo
- Publication number
- EP2057190A4 EP2057190A4 EP07840833A EP07840833A EP2057190A4 EP 2057190 A4 EP2057190 A4 EP 2057190A4 EP 07840833 A EP07840833 A EP 07840833A EP 07840833 A EP07840833 A EP 07840833A EP 2057190 A4 EP2057190 A4 EP 2057190A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- monoclonal antibodies
- interferon alpha
- alpha monoclonal
- interferon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Transplantation (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83659906P | 2006-08-09 | 2006-08-09 | |
PCT/US2007/075616 WO2008021976A2 (en) | 2006-08-09 | 2007-08-09 | Anti-interferon alpha monoclonal antibodies and methods for use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2057190A2 EP2057190A2 (de) | 2009-05-13 |
EP2057190A4 true EP2057190A4 (de) | 2010-07-28 |
Family
ID=39082973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07840833A Withdrawn EP2057190A4 (de) | 2006-08-09 | 2007-08-09 | Monoklonale anti-interferon-alpha-antikörper und verwendungsverfahren dafür |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2057190A4 (de) |
JP (1) | JP5230022B2 (de) |
WO (1) | WO2008021976A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2431638C2 (ru) | 2005-02-10 | 2011-10-20 | Бэйлор Рисерч Инститьют | Моноклональные антитела против интерферона-альфа и способы применения |
AU2007327993B2 (en) * | 2006-12-06 | 2013-06-20 | Medimmune, Llc. | Methods of treating systemic lupus erythematosus |
EP2687232A1 (de) * | 2006-12-06 | 2014-01-22 | MedImmune, LLC | Verfahren zur Behandlung von systemischem Lupus erythematodes |
US8163885B2 (en) * | 2008-05-07 | 2012-04-24 | Argos Therapeutics, Inc. | Humanized antibodies against human interferon-alpha |
US8790651B2 (en) * | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
CN106589122B (zh) * | 2015-10-20 | 2020-10-27 | 中国人民解放军军事医学科学院生物工程研究所 | 人源抗人多亚型干扰素α抗体及其应用 |
MA52011A (fr) | 2018-03-16 | 2021-01-20 | Zoetis Services Llc | Vaccins peptidiques contre l'interleukine-31 |
US11530262B2 (en) | 2018-03-16 | 2022-12-20 | Zoetis Services Llc | Interleukin-31 monoclonal antibodies for veterinary use |
RU2737466C1 (ru) * | 2019-12-30 | 2020-11-30 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Гуманизированное нейтрализующее антитело к интерферону-бета человека |
CN112129952B (zh) * | 2020-09-21 | 2023-06-06 | 普健生物(武汉)科技有限公司 | 一种检测人可溶性cd14的化学发光试剂盒 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002066649A2 (en) * | 2001-02-22 | 2002-08-29 | Genentech, Inc. | ANTI-INTERFERON-α ANTIBODIES |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2431638C2 (ru) * | 2005-02-10 | 2011-10-20 | Бэйлор Рисерч Инститьют | Моноклональные антитела против интерферона-альфа и способы применения |
-
2007
- 2007-08-09 EP EP07840833A patent/EP2057190A4/de not_active Withdrawn
- 2007-08-09 WO PCT/US2007/075616 patent/WO2008021976A2/en active Search and Examination
- 2007-08-09 JP JP2009524004A patent/JP5230022B2/ja active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002066649A2 (en) * | 2001-02-22 | 2002-08-29 | Genentech, Inc. | ANTI-INTERFERON-α ANTIBODIES |
Non-Patent Citations (6)
Title |
---|
CHANG K C ET AL: "MOLECULAR AND FUNCTIONAL ANALYSIS OF THE VIRUS- AND INTERFERON-INDUCIBLE HUMAN MXA PROMOTER", ARCHIVES OF VIROLOGY, NEW YORK, NY, US, vol. 117, 1991, pages 1 - 15, XP008007812, ISSN: 0304-8608 * |
CHUNTHARAPAI ANAN ET AL: "Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: A candidate therapeutic for IDDM and SLE", CYTOKINE, ACADEMIC PRESS LTD, PHILADELPHIA, PA, US, vol. 15, no. 5, 7 September 2001 (2001-09-07), pages 250 - 260, XP002307361, ISSN: 1043-4666 * |
FRAY M D ET AL: "Validation of an Mx/CAT reporter gene assay for the quantification of bovine type-I interferon", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 249, no. 1-2, 1 March 2001 (2001-03-01), pages 235 - 244, XP004317487, ISSN: 0022-1759 * |
LITTLE M ET AL: "Of mice and men: hybridoma and recombinant antibodies", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 21, no. 8, 1 August 2000 (2000-08-01), pages 364 - 370, XP004215163, ISSN: 0167-5699 * |
OVERALL M L ET AL: "FUNCTIONAL ANALYSIS OF INTERFERON-ALPHA SUBTYPES USING MONOCLONAL ANTIBODIES TO INTERFERON-ALPHA4A-SUBTYPE REACTIVITY, NEUTRALISATION OF BIOLOGICAL ACTIVITIES AND EPITOPE ANALYSIS", MOLECULAR IMMUNOLOGY, ELMSFORD, NY, US, vol. 29, no. 3, 1992, pages 391 - 399, XP009001288, ISSN: 0161-5890 * |
RONNI T ET AL: "THE PROXIMAL INTERFERON-STIMULATED RESPONSE ELEMENTS ARE ESSENTIAL FOR INTERFERON RESPONSIVENESS: A PROMOTER ANALYSIS OF THE ANTIVIRAL MXA GENE", JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 18, no. 9, September 1998 (1998-09-01), pages 773 - 781, XP008007716, ISSN: 1079-9907 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008021976A2 (en) | 2008-02-21 |
JP2010500380A (ja) | 2010-01-07 |
WO2008021976A3 (en) | 2008-11-13 |
JP5230022B2 (ja) | 2013-07-10 |
EP2057190A2 (de) | 2009-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090303 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20100624 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 39/395 20060101ALI20100618BHEP Ipc: C07K 16/24 20060101AFI20100618BHEP |
|
17Q | First examination report despatched |
Effective date: 20110329 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20150714 |