EP2056870A4 - Trypanosome microsome system and uses thereof - Google Patents

Trypanosome microsome system and uses thereof

Info

Publication number
EP2056870A4
EP2056870A4 EP07811144A EP07811144A EP2056870A4 EP 2056870 A4 EP2056870 A4 EP 2056870A4 EP 07811144 A EP07811144 A EP 07811144A EP 07811144 A EP07811144 A EP 07811144A EP 2056870 A4 EP2056870 A4 EP 2056870A4
Authority
EP
European Patent Office
Prior art keywords
trypanosome
microsome system
microsome
trypanosome microsome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07811144A
Other languages
German (de)
French (fr)
Other versions
EP2056870A2 (en
Inventor
Kojo Mensa-Wilmot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Georgia
University of Georgia Research Foundation Inc UGARF
Original Assignee
University of Georgia
University of Georgia Research Foundation Inc UGARF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Georgia, University of Georgia Research Foundation Inc UGARF filed Critical University of Georgia
Publication of EP2056870A2 publication Critical patent/EP2056870A2/en
Publication of EP2056870A4 publication Critical patent/EP2056870A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10—Protozoa; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP07811144A 2006-08-07 2007-08-07 Trypanosome microsome system and uses thereof Withdrawn EP2056870A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83604506P 2006-08-07 2006-08-07
PCT/US2007/017555 WO2008021092A2 (en) 2006-08-07 2007-08-07 Trypanosome microsome system and uses thereof

Publications (2)

Publication Number Publication Date
EP2056870A2 EP2056870A2 (en) 2009-05-13
EP2056870A4 true EP2056870A4 (en) 2010-10-13

Family

ID=39082560

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07811144A Withdrawn EP2056870A4 (en) 2006-08-07 2007-08-07 Trypanosome microsome system and uses thereof

Country Status (3)

Country Link
EP (1) EP2056870A4 (en)
CA (1) CA2660010A1 (en)
WO (1) WO2008021092A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8246966B2 (en) * 2006-08-07 2012-08-21 University Of Georgia Research Foundation, Inc. Trypanosome microsome system and uses thereof
US8338433B2 (en) 2006-11-22 2012-12-25 University Of Georgia Research Foundation, Inc. Tyrosine kinase inhibitors as anti-kinetoplastid agents
CN103483341A (en) * 2013-08-14 2014-01-01 华东师范大学 2, 4-pyrrolidine-diketone compounds and synthesis method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1262556A2 (en) * 2001-06-01 2002-12-04 Fundacao de Amparo a Pesquisa do Estado de Sao Paolo Antimicrobial peptides and method for identifying and using such peptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1262556A2 (en) * 2001-06-01 2002-12-04 Fundacao de Amparo a Pesquisa do Estado de Sao Paolo Antimicrobial peptides and method for identifying and using such peptides

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AL-QAHTANI AHMED ET AL: "Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania", BIOCHEMICAL JOURNAL, vol. 331, no. 2, 15 April 1998 (1998-04-15), pages 521 - 529, XP002598249, ISSN: 0264-6021 *
DE LA CANAL L ET AL: "SYNTHESIS OF DOLICHOL DERIVATIVES IN TRYPANOSOMATIDS CHARACTERIZATION OF ENZYMATIC PATTERNS", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 262, no. 23, 1987, pages 11128 - 11133, XP002598247, ISSN: 0021-9258 *
EL MOUDNI B ET AL: "Purification and characterization of N-acetylglucosaminidase from Trypanosoma cruzi.", EXPERIMENTAL PARASITOLOGY JUL 1996 LNKD- PUBMED:8682185, vol. 83, no. 2, July 1996 (1996-07-01), pages 167 - 173, XP002598248, ISSN: 0014-4894 *
PATHAM BHARGAVI ET AL: "Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities", BIOCHEMICAL JOURNAL, vol. 419, no. Part 2, April 2009 (2009-04-01), pages 507 - 517, XP002598250 *
VIDUGIRIENE JOLANTA ET AL: "The GPI Anchor of Cell-Surface Proteins Is Synthesized on the Cytoplasmic Face of the Endoplasmic Reticulum", JOURNAL OF CELL BIOLOGY, vol. 127, no. 2, 1994, pages 333 - 341, XP002598246, ISSN: 0021-9525 *

Also Published As

Publication number Publication date
WO2008021092A8 (en) 2008-12-11
EP2056870A2 (en) 2009-05-13
WO2008021092A3 (en) 2008-09-25
CA2660010A1 (en) 2008-02-21
WO2008021092A2 (en) 2008-02-21

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Legal Events

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AX Request for extension of the european patent

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DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/00 20060101ALI20100830BHEP

Ipc: G01N 33/569 20060101ALI20100830BHEP

Ipc: A61K 39/00 20060101AFI20090127BHEP

A4 Supplementary search report drawn up and despatched

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