EP1989529A4 - Method of processing a biological and/or chemical sample - Google Patents

Method of processing a biological and/or chemical sample

Info

Publication number
EP1989529A4
EP1989529A4 EP06717154A EP06717154A EP1989529A4 EP 1989529 A4 EP1989529 A4 EP 1989529A4 EP 06717154 A EP06717154 A EP 06717154A EP 06717154 A EP06717154 A EP 06717154A EP 1989529 A4 EP1989529 A4 EP 1989529A4
Authority
EP
European Patent Office
Prior art keywords
biological
processing
chemical sample
sample
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06717154A
Other languages
German (de)
French (fr)
Other versions
EP1989529A1 (en
Inventor
Juergen Pipper
Tseng-Ming Hsieh
Pavel Neuzil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agency for Science Technology and Research Singapore
Original Assignee
Agency for Science Technology and Research Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency for Science Technology and Research Singapore filed Critical Agency for Science Technology and Research Singapore
Publication of EP1989529A1 publication Critical patent/EP1989529A1/en
Publication of EP1989529A4 publication Critical patent/EP1989529A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28009Magnetic properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/01Drops
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432Liposomes or microcapsules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP06717154A 2006-02-13 2006-02-13 Method of processing a biological and/or chemical sample Withdrawn EP1989529A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SG2006/000029 WO2007094739A1 (en) 2006-02-13 2006-02-13 Method of processing a biological and/or chemical sample

Publications (2)

Publication Number Publication Date
EP1989529A1 EP1989529A1 (en) 2008-11-12
EP1989529A4 true EP1989529A4 (en) 2010-09-01

Family

ID=38371823

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06717154A Withdrawn EP1989529A4 (en) 2006-02-13 2006-02-13 Method of processing a biological and/or chemical sample

Country Status (6)

Country Link
US (1) US8216855B2 (en)
EP (1) EP1989529A4 (en)
JP (1) JP2009526970A (en)
CN (1) CN101371124B (en)
BR (1) BRPI0621413A2 (en)
WO (1) WO2007094739A1 (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US8685754B2 (en) * 2006-04-18 2014-04-01 Advanced Liquid Logic, Inc. Droplet actuator devices and methods for immunoassays and washing
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8389297B2 (en) * 2006-04-18 2013-03-05 Duke University Droplet-based affinity assay device and system
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US9675972B2 (en) * 2006-05-09 2017-06-13 Advanced Liquid Logic, Inc. Method of concentrating beads in a droplet
EP2081686A4 (en) * 2006-09-29 2010-05-05 Ge Healthcare Bio Sciences Ab Method and device for small scale reactions
CA2629589C (en) * 2007-04-20 2016-03-29 F.Hoffmann-La Roche Ag Isolation and purification of nucleic acid molecules with a solid phase
WO2008134153A1 (en) * 2007-04-23 2008-11-06 Advanced Liquid Logic, Inc. Bead-based multiplexed analytical methods and instrumentation
US20090263870A1 (en) * 2007-09-10 2009-10-22 Agency For Science, Technology And Research System and method for amplifying a nucleic acid molecule
AU2008340098B2 (en) * 2007-12-20 2014-09-04 Proionic Gmbh Use of magnetic, ionic liquids as an extraction agent
US8617899B2 (en) * 2008-02-14 2013-12-31 Palo Alto Research Center Incorporated Enhanced drop mixing using magnetic actuation
WO2009111316A2 (en) * 2008-02-29 2009-09-11 Northwestern University Barriers for facilitating biological reactions
EP2279405B1 (en) * 2008-05-13 2013-09-18 Advanced Liquid Logic, Inc. Droplet actuator devices, systems, and methods
JP5504587B2 (en) * 2008-05-27 2014-05-28 東レ株式会社 Analysis chip
AU2009320152B2 (en) 2008-10-27 2015-01-29 Advantageous Systems, Llc Liquid purification using magnetic nanoparticles
CA2761276C (en) * 2009-05-15 2017-06-27 Gen-Probe Incorporated Method and apparatus for effecting automated movement of a magnet in an instrument for performing a magnetic separation procedure
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
JP5763652B2 (en) * 2009-10-06 2015-08-12 コーニンクレッカ フィリップス エヌ ヴェ Purification of magnetic samples
WO2011057197A2 (en) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel electrophoresis and molecular analysis
TWI385029B (en) * 2009-12-18 2013-02-11 Univ Nat Chiao Tung Microfluidic system and method for creating an encapsulated droplet with a removable shell
BR112012026003B1 (en) 2010-04-13 2022-03-15 Medimmune, Llc Trail r2 specific recombinant multimeric structure, its use as well as composition
JP5573335B2 (en) * 2010-04-28 2014-08-20 株式会社島津製作所 Magnetic particle manipulation device and magnetic particle manipulation method
US20130149710A1 (en) * 2010-09-07 2013-06-13 The Arizona Board Of Regents On Behalf Of The University Of Arizona Microdroplet-manipulation systems and methods for automated execution of molecular biological protocols
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
KR20220012400A (en) * 2011-08-05 2022-02-03 메사추세츠 인스티튜트 오브 테크놀로지 Devices incorporating a liquid-impregnated surface
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
CN103076416B (en) * 2011-11-15 2014-08-06 南昌大学 Method for enriching clenbuterol, ractopamine and salbutamol in urine sample of breeding livestock
KR102070556B1 (en) 2012-03-23 2020-01-29 메사추세츠 인스티튜트 오브 테크놀로지 Self-lubricating surfaces for food packaging and processing equipment
EP2846910B1 (en) 2012-05-08 2016-12-21 Quidel Corporation Device and method for isolating an analyte from a sample
US20130337027A1 (en) 2012-05-24 2013-12-19 Massachusetts Institute Of Technology Medical Devices and Implements with Liquid-Impregnated Surfaces
US9625075B2 (en) 2012-05-24 2017-04-18 Massachusetts Institute Of Technology Apparatus with a liquid-impregnated surface to facilitate material conveyance
EP2861346B1 (en) 2012-06-13 2016-08-17 Massachusetts Institute of Technology Articles and methods for levitating liquids on surfaces, and devices incorporating the same
US10501735B2 (en) 2012-08-23 2019-12-10 Quidel Corporation Device with controlled fluid dynamics, for isolation of an analyte from a sample
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
GB201219196D0 (en) * 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
US20140178611A1 (en) 2012-11-19 2014-06-26 Massachusetts Institute Of Technology Apparatus and methods employing liquid-impregnated surfaces
BR112015011378A8 (en) 2012-11-19 2019-10-01 Massachusetts Inst Technology article comprising a liquid impregnated surface and method of using said article
CN105188934B (en) 2012-12-07 2018-12-04 牛津大学创新有限公司 The drop component of 3D printing
FR3002634B1 (en) * 2013-02-28 2015-04-10 Commissariat Energie Atomique METHOD OF OBSERVING AT LEAST ONE OBJECT, SUCH AS A BIOLOGICAL ENTITY, AND ASSOCIATED IMAGING SYSTEM
US9791265B2 (en) * 2013-05-31 2017-10-17 University Of North Carolina At Charlotte Methods of determining the shape of a sessile drop
TWI529402B (en) 2013-07-26 2016-04-11 財團法人工業技術研究院 Magnetic beads manipulating device and method for manipulating magnetic beads
WO2015061362A1 (en) 2013-10-21 2015-04-30 The Regents Of The University Of California Enrichment and detection of nucleic acids with ultra-high sensitivity
US9463461B2 (en) 2013-10-25 2016-10-11 The Johns Hopkins University Self-contained cartridge and methods for integrated biochemical assay at the point-of-care
CN104111333A (en) * 2013-11-13 2014-10-22 叶森 Fast erythrocyte removal method applicable to whole blood detection
US10379093B2 (en) 2013-12-06 2019-08-13 Battelle Memorial Institute Method and device for detecting odorants in hydrocarbon gases
US10128078B2 (en) * 2014-01-29 2018-11-13 Japan Science And Technology Agency Protective agent for electron microscopic observation of biological sample in water-containing state, kit for electron microscopic observation, methods for observation, diagnosis, evaluation, and quantification by electron microscope, and sample stage
DE102014209720B4 (en) * 2014-05-22 2016-09-22 Henkel Ag & Co. Kgaa Method for determining the effectiveness of a hair treatment substance and holding device for carrying out the method
CA2993401C (en) 2014-10-28 2018-09-18 The Governing Council Of The University Of Toronto Electrochemical metabolic activity detecting device
CN104697830B (en) * 2015-02-10 2018-06-15 深圳市新产业生物医学工程股份有限公司 For acidic treatment agent, sample preprocessing method, kit and the detection method of HIV detections
CN105435867B (en) * 2015-10-26 2018-05-22 深圳华迈兴微医疗科技有限公司 Detect the magnetic microparticle chemiluminescence micro-fluidic chip of creatine kinase isozyme in whole blood
CN107190050B (en) * 2016-03-14 2020-10-27 华东理工大学 HRP activity determination and H2O2Concentration detection kit and application thereof
WO2018070222A1 (en) * 2016-10-13 2018-04-19 パナソニックIpマネジメント株式会社 Biomolecule extraction method, extraction system, and extraction container
CN107024465A (en) * 2017-04-21 2017-08-08 深圳大学 A kind of method of Raman spectrometer sample stage and its in-situ test spectrum
GB2562314A (en) * 2017-05-13 2018-11-14 Cyanoguard Ag Process
CN109317225A (en) * 2017-07-31 2019-02-12 中国科学院大连化学物理研究所 It is a kind of based on digital microcurrent-controlled moveable magnet device
CN107859562A (en) * 2017-11-30 2018-03-30 河海大学 A kind of magnetic fluid multipaths ternary catalyzing unit purging system and its cleaning method
EP3759213A4 (en) * 2018-03-02 2022-03-16 Quantumcyte, Inc. Methods, compositions, and devices for isolation and expression analysis of regions of interest from a tissue
JP2021515596A (en) * 2018-03-03 2021-06-24 ラブサイト インコーポレイテッド Systems and methods for extracting target moieties from a sample using acoustic droplet ejection
EP3824484A1 (en) * 2018-07-19 2021-05-26 Beckman Coulter Inc. Magnetic particles
CN109127692B (en) * 2018-09-05 2020-11-20 日照盛恒环保科技有限公司 Can be to filterable soil prosthetic devices of metallic element
WO2020079533A1 (en) * 2018-10-17 2020-04-23 Abdolahad Mohammad Electrochemical lipidomics for cancer diagnosis
CN109331996B (en) * 2018-11-06 2024-05-14 中南大学 Single-sided toothed plate medium, double-sided toothed plate medium, toothed plate medium box and flat ring high intensity magnetic separator
CN109470804B (en) * 2018-12-11 2021-08-31 温州医科大学 Application of double-positive imidazolium salt ionic liquid in extraction of bisphenol compounds and micro-extraction technology based on ionic liquid
CN110082063A (en) * 2019-03-04 2019-08-02 中国科学院化学研究所 The method and purposes of rotary motion after a kind of control droplet collision
US11267707B2 (en) * 2019-04-16 2022-03-08 Honeywell International Inc Purification of bis(fluorosulfonyl) imide
CN110354826B (en) * 2019-07-29 2021-12-14 肇庆学院 Lead-cadmium ion double-template magnetic molecularly imprinted polymer and preparation method thereof
CN111627827A (en) * 2020-06-05 2020-09-04 中国科学院物理研究所 Method for judging polar surface of single crystal by using wettability difference
CN113514297A (en) * 2021-06-21 2021-10-19 福建农林大学 Magnetic control molecular combing method for stretching single molecular DNA
CN114624225B (en) * 2022-05-16 2022-07-29 南京邮电大学 Membrane protein dimer in-situ detection kit and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02141667A (en) * 1988-11-22 1990-05-31 Olympus Optical Co Ltd Particle of blood corpuscle
US5993665A (en) * 1996-06-07 1999-11-30 Immunivest Corporation Quantitative cell analysis methods employing magnetic separation
US20050003380A1 (en) * 2001-06-18 2005-01-06 Medical Research Council Selective gene amplification
WO2005069015A1 (en) * 2004-01-15 2005-07-28 Japan Science And Technology Agency Chemical analysis apparatus and method of chemical analysis
US20050266478A1 (en) * 2002-01-24 2005-12-01 Mingxian Huang Biochips including ion transport detecting structures and methods of use

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3139004B2 (en) * 1990-04-20 2001-02-26 東レ株式会社 Cell culture substrate and cell culture method using the same
DE4237113B4 (en) 1992-11-03 2006-10-12 "Iba Gmbh" Peptides and their fusion proteins, expression vector and method of producing a fusion protein
WO1996023879A1 (en) 1995-01-30 1996-08-08 Terrapin Technologies, Inc. Glubodies - multiplicities of proteins capable of binding a variety of small molecules
US5854063A (en) * 1996-01-16 1998-12-29 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method and apparatus for spectrophotometric observation of plants
DE19641876B4 (en) 1996-10-10 2011-09-29 Iba Gmbh streptavidin muteins
DE19742706B4 (en) 1997-09-26 2013-07-25 Pieris Proteolab Ag lipocalin muteins
GB9900298D0 (en) 1999-01-07 1999-02-24 Medical Res Council Optical sorting method
JP4582914B2 (en) * 1999-04-06 2010-11-17 イー インク コーポレイション Method for making droplets for use in capsule-based electromotive displays
US20040038192A1 (en) * 1999-04-14 2004-02-26 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
DE19926068C1 (en) 1999-06-08 2001-01-11 Arne Skerra Muteins of the bilin binding protein
DE19932688B4 (en) 1999-07-13 2009-10-08 Scil Proteins Gmbh Design of beta-sheet proteins of gamma-II-crystalline antibody-like
DE10113776B4 (en) 2001-03-21 2012-08-09 "Iba Gmbh" Isolated streptavidin-binding, competitively elutable peptide, this comprehensive fusion peptide, nucleic acid coding therefor, expression vector, methods for producing a recombinant fusion protein and methods for detecting and / or obtaining the fusion protein
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
EP1430136A1 (en) 2001-09-27 2004-06-23 Pieris ProteoLab AG Muteins of apolipoprotein d
WO2003029462A1 (en) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
US6991825B2 (en) 2002-05-10 2006-01-31 Asm Assembly Automation Ltd. Dispensation of controlled quantities of material onto a substrate
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US7588311B2 (en) * 2003-03-24 2009-09-15 Canon Kabushiki Kaisha Discharging apparatus and removing method
AU2003275958A1 (en) 2003-08-25 2005-03-10 Pieris Proteolab Ag Muteins of tear lipocalin
AU2003264100A1 (en) 2003-08-25 2005-03-10 Pieris Proteolab Ag Muteins of a bilin-binding protein with affinity for a given target
KR20070029618A (en) * 2003-08-27 2007-03-14 더 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Electronic control of fluidic species
US7582858B2 (en) * 2004-01-23 2009-09-01 Sri International Apparatus and method of moving micro-droplets using laser-induced thermal gradients
US20050249882A1 (en) 2004-05-04 2005-11-10 Shaorong Liu Coatings for molecule transport and separations
KR101544351B1 (en) * 2005-02-18 2015-08-13 캐논 유.에스. 라이프 사이언시즈, 인크. Devices and methods for identifying genomic dna of organisms

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02141667A (en) * 1988-11-22 1990-05-31 Olympus Optical Co Ltd Particle of blood corpuscle
US5993665A (en) * 1996-06-07 1999-11-30 Immunivest Corporation Quantitative cell analysis methods employing magnetic separation
US20050003380A1 (en) * 2001-06-18 2005-01-06 Medical Research Council Selective gene amplification
US20050266478A1 (en) * 2002-01-24 2005-12-01 Mingxian Huang Biochips including ion transport detecting structures and methods of use
WO2005069015A1 (en) * 2004-01-15 2005-07-28 Japan Science And Technology Agency Chemical analysis apparatus and method of chemical analysis
EP1707965A1 (en) * 2004-01-15 2006-10-04 Japan Science and Technology Agency Chemical analysis apparatus and method of chemical analysis

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BERNATH K ET AL: "In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, vol. 325, no. 1, 1 February 2004 (2004-02-01), pages 151 - 157, XP004483545, ISSN: 0003-2697, DOI: 10.1016/J.AB.2003.10.005 *
GRIFFITHS A D ET AL: "Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 22, no. 1, 2 January 2003 (2003-01-02), pages 24 - 35, XP002272486, ISSN: 0261-4189, DOI: 10.1093/EMBOJ/CDG014 *
NICOLE PAMME: "Magnetism and microfluidics", LAB CHIP, vol. 6, 28 November 2005 (2005-11-28), pages 24 - 38, XP002591314 *
O'HARE ET AL: "The Laboratory in a Droplet", CHEMISTRY AND BIOLOGY, CURRENT BIOLOGY, LONDON, GB, vol. 12, no. 12, 1 December 2005 (2005-12-01), pages 1255 - 1257, XP005210938, ISSN: 1074-5521, DOI: 10.1016/J.CHEMBIOL.2005.11.006 *
See also references of WO2007094739A1 *
SPENCER ROACH L ET AL: "Controlling Nonspecific Protein Adsorption in a Plug-Based Microfluidic System by Controlling Interfacial Chemistry Using Fluorous-Phase Surfactants", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US LNKD- DOI:10.1021/AC049061W, vol. 77, no. 3, 1 February 2005 (2005-02-01), pages 785 - 796, XP002527289, ISSN: 0003-2700, [retrieved on 20041230] *

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