EP1974814A1 - Mikrofluidische Vorrichtung auf der Basis von Aktivmatrixprinzipien - Google Patents

Mikrofluidische Vorrichtung auf der Basis von Aktivmatrixprinzipien Download PDF

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Publication number
EP1974814A1
EP1974814A1 EP07104818A EP07104818A EP1974814A1 EP 1974814 A1 EP1974814 A1 EP 1974814A1 EP 07104818 A EP07104818 A EP 07104818A EP 07104818 A EP07104818 A EP 07104818A EP 1974814 A1 EP1974814 A1 EP 1974814A1
Authority
EP
European Patent Office
Prior art keywords
micro
fluid
fluidic device
fluidic
active matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07104818A
Other languages
English (en)
French (fr)
Inventor
designation of the inventor has not yet been filed The
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics NV filed Critical Koninklijke Philips Electronics NV
Priority to EP07104818A priority Critical patent/EP1974814A1/de
Publication of EP1974814A1 publication Critical patent/EP1974814A1/de
Ceased legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006Micropumps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • B01L2200/147Employing temperature sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • B01L2400/0448Marangoni flow; Thermocapillary effect
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • B01L2400/0451Thermophoresis; Thermodiffusion; Soret-effect
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP07104818A 2007-03-23 2007-03-23 Mikrofluidische Vorrichtung auf der Basis von Aktivmatrixprinzipien Ceased EP1974814A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07104818A EP1974814A1 (de) 2007-03-23 2007-03-23 Mikrofluidische Vorrichtung auf der Basis von Aktivmatrixprinzipien

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07104818A EP1974814A1 (de) 2007-03-23 2007-03-23 Mikrofluidische Vorrichtung auf der Basis von Aktivmatrixprinzipien

Publications (1)

Publication Number Publication Date
EP1974814A1 true EP1974814A1 (de) 2008-10-01

Family

ID=39302991

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07104818A Ceased EP1974814A1 (de) 2007-03-23 2007-03-23 Mikrofluidische Vorrichtung auf der Basis von Aktivmatrixprinzipien

Country Status (1)

Country Link
EP (1) EP1974814A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2353716A1 (de) 2010-02-05 2011-08-10 Ludwig-Maximilians-Universität München Verfahren und Vorrichtung zur Amplifikation von Nukleinsäuresequenzen
WO2013128322A1 (en) 2012-02-27 2013-09-06 Ecole Polytechnique Federale De Lausanne (Epfl) Sample processing device with detachable slide
CN115007233A (zh) * 2017-10-18 2022-09-06 核酸有限公司 包括具有薄膜晶体管和电容感测的双基底的数字微流体设备

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846396A (en) * 1994-11-10 1998-12-08 Sarnoff Corporation Liquid distribution system
US20020150683A1 (en) * 2000-11-02 2002-10-17 Troian Sandra M. Method and device for controlling liquid flow on the surface of a microfluidic chip
US20060134683A1 (en) * 2001-10-23 2006-06-22 Michael Sogard Methods and devices for hybridization and binding assays using thermophoresis
WO2007004153A2 (en) * 2005-07-05 2007-01-11 Koninklijke Philips Electronics N.V. Device for the controlled release of a predefined quantity of a substance
WO2007034437A2 (en) * 2005-09-23 2007-03-29 Koninklijke Philips Electronics N.V. A micro-fluidic device based upon active matrix principles

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846396A (en) * 1994-11-10 1998-12-08 Sarnoff Corporation Liquid distribution system
US20020150683A1 (en) * 2000-11-02 2002-10-17 Troian Sandra M. Method and device for controlling liquid flow on the surface of a microfluidic chip
US20060134683A1 (en) * 2001-10-23 2006-06-22 Michael Sogard Methods and devices for hybridization and binding assays using thermophoresis
WO2007004153A2 (en) * 2005-07-05 2007-01-11 Koninklijke Philips Electronics N.V. Device for the controlled release of a predefined quantity of a substance
WO2007034437A2 (en) * 2005-09-23 2007-03-29 Koninklijke Philips Electronics N.V. A micro-fluidic device based upon active matrix principles
WO2007034374A2 (en) * 2005-09-23 2007-03-29 Koninklijke Philips Electronics N.V. A micro-fluidic device based upon active matrix principles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRAUN D., LIBCHABER A., PHYSICAL REVIEW LETTER, vol. 89, no. 18, 28 October 2002 (2002-10-28), pages 188103-1 - 188103-4, XP002479046 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2353716A1 (de) 2010-02-05 2011-08-10 Ludwig-Maximilians-Universität München Verfahren und Vorrichtung zur Amplifikation von Nukleinsäuresequenzen
EP2353720A3 (de) * 2010-02-05 2014-03-12 Ludwig-Maximilians-Universität München Verfahren und Vorrichtung zur Amplifikation von Nukleinsäuresequenzen
WO2013128322A1 (en) 2012-02-27 2013-09-06 Ecole Polytechnique Federale De Lausanne (Epfl) Sample processing device with detachable slide
US10436683B2 (en) 2012-02-27 2019-10-08 Ecole Polytechnique Federale De Lausanne (Epfl) Sample processing device with detachable slide
CN115007233A (zh) * 2017-10-18 2022-09-06 核酸有限公司 包括具有薄膜晶体管和电容感测的双基底的数字微流体设备
CN115007233B (zh) * 2017-10-18 2023-11-10 核蛋白有限公司 包括具有薄膜晶体管和电容感测的双基底的数字微流体设备

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