EP1948792A4 - Conditionally replicating viruses and methods for cancer virotherapy - Google Patents

Conditionally replicating viruses and methods for cancer virotherapy

Info

Publication number
EP1948792A4
EP1948792A4 EP05824940A EP05824940A EP1948792A4 EP 1948792 A4 EP1948792 A4 EP 1948792A4 EP 05824940 A EP05824940 A EP 05824940A EP 05824940 A EP05824940 A EP 05824940A EP 1948792 A4 EP1948792 A4 EP 1948792A4
Authority
EP
European Patent Office
Prior art keywords
methods
conditionally replicating
replicating viruses
cancer virotherapy
virotherapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05824940A
Other languages
German (de)
French (fr)
Other versions
EP1948792A1 (en
Inventor
James Michael Mathis
Arrigo Debenedetti
David T Curiel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1948792A1 publication Critical patent/EP1948792A1/en
Publication of EP1948792A4 publication Critical patent/EP1948792A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2820/00—Vectors comprising a special origin of replication system
    • C12N2820/002—Vectors comprising a special origin of replication system inducible or controllable
EP05824940A 2005-10-28 2005-10-28 Conditionally replicating viruses and methods for cancer virotherapy Withdrawn EP1948792A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2005/038918 WO2007050074A1 (en) 2005-10-28 2005-10-28 Conditionally replicating viruses and methods for cancer virotherapy

Publications (2)

Publication Number Publication Date
EP1948792A1 EP1948792A1 (en) 2008-07-30
EP1948792A4 true EP1948792A4 (en) 2010-08-04

Family

ID=37968085

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05824940A Withdrawn EP1948792A4 (en) 2005-10-28 2005-10-28 Conditionally replicating viruses and methods for cancer virotherapy

Country Status (5)

Country Link
EP (1) EP1948792A4 (en)
JP (1) JP2009513133A (en)
AU (1) AU2005337612A1 (en)
CA (1) CA2627638A1 (en)
WO (1) WO2007050074A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107349226B (en) 2014-08-26 2020-08-25 广州威溶特医药科技有限公司 Application of alphavirus in preparing anti-tumor medicine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759394B2 (en) * 2001-07-26 2004-07-06 Board Of Supervisors Of La. State Un. & Agricultural And Mechanical College Cancer gene therapy based on translational control of a suicide gene

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030017138A1 (en) * 1998-07-08 2003-01-23 Menzo Havenga Chimeric adenoviruses
AU4250600A (en) * 1999-04-21 2000-11-02 Genzyme Corporation Adenoviral vectors having nucleic acids encoding immunomodulatory molecules

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759394B2 (en) * 2001-07-26 2004-07-06 Board Of Supervisors Of La. State Un. & Agricultural And Mechanical College Cancer gene therapy based on translational control of a suicide gene

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
AHMED A ET AL: "A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P- MAPK-selective mRNA stabilization", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US LNKD- DOI:10.1038/NBT835, vol. 21, no. 7, 1 July 2003 (2003-07-01), pages 771 - 777, XP002977838, ISSN: 1087-0156 *
DEFATTA ROBERT J ET AL: "A cancer gene therapy approach through translational control of a suicide gene.", CANCER GENE THERAPY JUN 2002 LNKD- PUBMED:12032661, vol. 9, no. 6, June 2002 (2002-06-01), pages 505 - 512, XP002587285, ISSN: 0929-1903 *
DEFATTA ROBERT J ET AL: "Selective killing of cancer cells based on translational control of a suicide gene", CANCER GENE THERAPY, vol. 9, no. 7, July 2002 (2002-07-01), pages 573 - 578, XP002587284, ISSN: 0929-1903 *
MATHIS J MICHAEL ET AL: "Cancer-specific targeting of an adenovirus-delivered herpes simplex virus thymidine kinase suicide gene using translational control.", THE JOURNAL OF GENE MEDICINE SEP 2006 LNKD- PUBMED:16802401, vol. 8, no. 9, September 2006 (2006-09-01), pages 1105 - 1120, XP002587286, ISSN: 1099-498X *
See also references of WO2007050074A1 *
TUXWORTH WILLIAM J JR ET AL: "Regulation of protein synthesis by eIF4E phosphorylation in adult cardiocytes: the consequence of secondary structure in the 5'-untranslated region of mRNA.", THE BIOCHEMICAL JOURNAL 15 FEB 2004 LNKD- PUBMED:14629199, vol. 378, no. Pt 1, 15 February 2004 (2004-02-15), pages 73 - 82, XP002587287, ISSN: 1470-8728 *
YU D ET AL: "Targeting and killing of prostate cancer cells using lentiviral constructs containing a sequence recognized by translation factor eIF4E and a prostate-specific promoter", CANCER GENE THERAPY, vol. 13, no. 1, 29 July 2005 (2005-07-29), pages 32 - 43, XP002587283, ISSN: 0929-1903 *

Also Published As

Publication number Publication date
WO2007050074A1 (en) 2007-05-03
AU2005337612A8 (en) 2008-07-03
CA2627638A1 (en) 2007-05-03
EP1948792A1 (en) 2008-07-30
AU2005337612A1 (en) 2007-05-03
JP2009513133A (en) 2009-04-02

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