EP1947938A4 - Makrocyclische formulierungen für die transmembranale arzneistoffabgabe - Google Patents

Makrocyclische formulierungen für die transmembranale arzneistoffabgabe

Info

Publication number
EP1947938A4
EP1947938A4 EP06827385A EP06827385A EP1947938A4 EP 1947938 A4 EP1947938 A4 EP 1947938A4 EP 06827385 A EP06827385 A EP 06827385A EP 06827385 A EP06827385 A EP 06827385A EP 1947938 A4 EP1947938 A4 EP 1947938A4
Authority
EP
European Patent Office
Prior art keywords
macrocyclic
formulations
drug delivery
transmembrane drug
transmembrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06827385A
Other languages
English (en)
French (fr)
Other versions
EP1947938A2 (de
Inventor
Robert J Gyurik
Carl Reppucci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CPEX Pharmaceuticals Inc
Original Assignee
CPEX Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CPEX Pharmaceuticals Inc filed Critical CPEX Pharmaceuticals Inc
Publication of EP1947938A2 publication Critical patent/EP1947938A2/de
Publication of EP1947938A4 publication Critical patent/EP1947938A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP06827385A 2005-11-02 2006-11-02 Makrocyclische formulierungen für die transmembranale arzneistoffabgabe Withdrawn EP1947938A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26571105A 2005-11-02 2005-11-02
PCT/US2006/042827 WO2007056068A2 (en) 2005-11-02 2006-11-02 Macrocyclic formulations for transmembrane drug delivery

Publications (2)

Publication Number Publication Date
EP1947938A2 EP1947938A2 (de) 2008-07-30
EP1947938A4 true EP1947938A4 (de) 2009-07-01

Family

ID=38023806

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06827385A Withdrawn EP1947938A4 (de) 2005-11-02 2006-11-02 Makrocyclische formulierungen für die transmembranale arzneistoffabgabe

Country Status (2)

Country Link
EP (1) EP1947938A4 (de)
WO (1) WO2007056068A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2578426C2 (ru) * 2010-06-28 2016-03-27 Эдитерапьютикс, Инк. Лечение келоидов
US9744156B2 (en) * 2015-08-17 2017-08-29 Arno Therapeutics, Inc. Methods and compositions for enhanced transungual delivery of AR-12

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011015A1 (en) * 1993-10-22 1995-04-27 Elson Melvin L Composition and method for treating blood vessel disorders of the skin using vitamin k
WO1996006636A1 (en) * 1994-08-26 1996-03-07 Wilson Trafton Crandall Topical anti-inflammatory composition and method
US5817699A (en) * 1997-05-30 1998-10-06 Flores; John A. Process for the preparation of ketamine ointment
US5837289A (en) * 1996-07-23 1998-11-17 Grasela; John C. Transdermal delivery of medications using a combination of penetration enhancers
WO1999011208A1 (en) * 1997-08-28 1999-03-11 Williams C Donald Method and composition for transdermal administration of pharmacologic agents
US5945409A (en) * 1995-03-10 1999-08-31 Wilson T. Crandall Topical moisturizing composition and method
WO2001060325A1 (en) * 2000-02-16 2001-08-23 Bentley Pharmaceuticals, Inc. Pharmaceutical composition
US20050123592A1 (en) * 2003-12-08 2005-06-09 Gyurik Robert J. Pharmaceutical compositions and methods for insulin treatment

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011015A1 (en) * 1993-10-22 1995-04-27 Elson Melvin L Composition and method for treating blood vessel disorders of the skin using vitamin k
WO1996006636A1 (en) * 1994-08-26 1996-03-07 Wilson Trafton Crandall Topical anti-inflammatory composition and method
US5945409A (en) * 1995-03-10 1999-08-31 Wilson T. Crandall Topical moisturizing composition and method
US5837289A (en) * 1996-07-23 1998-11-17 Grasela; John C. Transdermal delivery of medications using a combination of penetration enhancers
US5817699A (en) * 1997-05-30 1998-10-06 Flores; John A. Process for the preparation of ketamine ointment
WO1999011208A1 (en) * 1997-08-28 1999-03-11 Williams C Donald Method and composition for transdermal administration of pharmacologic agents
WO2001060325A1 (en) * 2000-02-16 2001-08-23 Bentley Pharmaceuticals, Inc. Pharmaceutical composition
US20050123592A1 (en) * 2003-12-08 2005-06-09 Gyurik Robert J. Pharmaceutical compositions and methods for insulin treatment

Also Published As

Publication number Publication date
WO2007056068A3 (en) 2007-09-27
WO2007056068A2 (en) 2007-05-18
EP1947938A2 (de) 2008-07-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20080602

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CPEX PHARMACEUTICALS, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20090604

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 9/06 20060101AFI20090528BHEP

Ipc: A61K 47/10 20060101ALI20090528BHEP

Ipc: A61K 31/4174 20060101ALI20090528BHEP

Ipc: A61K 47/14 20060101ALI20090528BHEP

Ipc: A61K 31/137 20060101ALI20090528BHEP

Ipc: A61K 47/24 20060101ALI20090528BHEP

17Q First examination report despatched

Effective date: 20090909

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18D Application deemed to be withdrawn

Effective date: 20140920