EP1940417A4 - Method of treating clostridium difficile-associated diarrhea - Google Patents

Method of treating clostridium difficile-associated diarrhea

Info

Publication number
EP1940417A4
EP1940417A4 EP06826544A EP06826544A EP1940417A4 EP 1940417 A4 EP1940417 A4 EP 1940417A4 EP 06826544 A EP06826544 A EP 06826544A EP 06826544 A EP06826544 A EP 06826544A EP 1940417 A4 EP1940417 A4 EP 1940417A4
Authority
EP
European Patent Office
Prior art keywords
clostridium difficile
associated diarrhea
treating clostridium
treating
diarrhea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06826544A
Other languages
German (de)
French (fr)
Other versions
EP1940417A2 (en
Inventor
Pamela Sears
Youe-Kong Shue
Starr Louise Miller-Shangle
Robert Brian Walsh
Farah Babakhani
Yu-Hung Chiu
Alex Romero
Sherwood Gorbach
Thomas John Louie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Optimer Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optimer Pharmaceuticals LLC filed Critical Optimer Pharmaceuticals LLC
Publication of EP1940417A2 publication Critical patent/EP1940417A2/en
Publication of EP1940417A4 publication Critical patent/EP1940417A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP06826544A 2005-10-21 2006-10-23 Method of treating clostridium difficile-associated diarrhea Withdrawn EP1940417A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72913505P 2005-10-21 2005-10-21
US74964105P 2005-12-12 2005-12-12
PCT/US2006/041436 WO2007048059A2 (en) 2005-10-21 2006-10-23 Method of treating clostridium difficile-associated diarrhea

Publications (2)

Publication Number Publication Date
EP1940417A2 EP1940417A2 (en) 2008-07-09
EP1940417A4 true EP1940417A4 (en) 2010-07-07

Family

ID=37963388

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06826544A Withdrawn EP1940417A4 (en) 2005-10-21 2006-10-23 Method of treating clostridium difficile-associated diarrhea

Country Status (8)

Country Link
EP (1) EP1940417A4 (en)
JP (1) JP2009512691A (en)
KR (1) KR101399621B1 (en)
CN (2) CN101340919B (en)
AU (1) AU2006304868B2 (en)
CA (1) CA2626698C (en)
HK (1) HK1126410A1 (en)
WO (1) WO2007048059A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7906489B2 (en) 2004-05-14 2011-03-15 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof
US7378508B2 (en) 2007-01-22 2008-05-27 Optimer Pharmaceuticals, Inc. Polymorphic crystalline forms of tiacumicin B
TWI523654B (en) 2007-11-27 2016-03-01 默沙東藥廠 Antibiotic macrocycle compounds and methods of manufacture and use thereof
JO3464B1 (en) 2013-01-15 2020-07-05 Astellas Pharma Europe Ltd Compositions of Tiacumicin Compounds
CN104846044B (en) * 2014-02-17 2019-02-01 上海医药工业研究院 A kind of fermentation medium improving feldamycin yield
CN105237599B (en) * 2015-10-09 2018-10-02 华北制药集团新药研究开发有限责任公司 New Year Amycin A4 crystal and preparation method thereof
CN107714713B (en) * 2017-10-25 2020-05-26 中山大学 Application of tiacumicin derivative in preparation of medicine for treating related diseases and/or symptoms caused by dengue virus infection
CN107970253B (en) * 2017-10-25 2020-05-26 中山大学 Application of tiacumicin derivative in preparation of medicine for treating related diseases and/or symptoms caused by Zika virus infection
WO2019236806A1 (en) * 2018-06-07 2019-12-12 Artugen Therapeutics Ltd. Methods and compositions for the treatment of c. difficile

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583115A (en) * 1995-05-09 1996-12-10 Abbott Laboratories Dialkyltiacumicin compounds
WO2005112990A2 (en) * 2004-05-14 2005-12-01 Optimer Pharmaceuticals, Inc. Treatment of diseases associated with the use of antibiotics
WO2006085838A1 (en) * 2005-01-31 2006-08-17 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918174A (en) 1986-09-26 1990-04-17 Abbott Laboratories Tiacumicin compounds
KR100972542B1 (en) * 2002-07-29 2010-07-28 옵티머 파마슈티칼즈, 인코포레이티드 Tiacumicin production

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583115A (en) * 1995-05-09 1996-12-10 Abbott Laboratories Dialkyltiacumicin compounds
WO2005112990A2 (en) * 2004-05-14 2005-12-01 Optimer Pharmaceuticals, Inc. Treatment of diseases associated with the use of antibiotics
WO2006085838A1 (en) * 2005-01-31 2006-08-17 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof

Also Published As

Publication number Publication date
AU2006304868A1 (en) 2007-04-26
CN101340919B (en) 2011-12-07
KR20080064177A (en) 2008-07-08
CN102503994A (en) 2012-06-20
CN101340919A (en) 2009-01-07
CA2626698C (en) 2015-12-01
HK1126410A1 (en) 2009-09-04
WO2007048059A3 (en) 2007-05-31
KR101399621B1 (en) 2014-06-18
JP2009512691A (en) 2009-03-26
WO2007048059A2 (en) 2007-04-26
CA2626698A1 (en) 2007-04-26
EP1940417A2 (en) 2008-07-09
AU2006304868B2 (en) 2013-02-21

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080425

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20100609

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 31/04 20060101ALI20100602BHEP

Ipc: A61K 45/06 20060101ALI20100602BHEP

Ipc: A61K 31/70 20060101AFI20080428BHEP

17Q First examination report despatched

Effective date: 20110216

17Q First examination report despatched

Effective date: 20110302

DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: OPTIMER PHARMACEUTICALS, INC.

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: MERCK SHARP & DOHME CORP.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20160202