EP1934614A4 - Reagents for the detection of protein phosphorylation in carcinoma signaling pathways - Google Patents

Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Info

Publication number
EP1934614A4
EP1934614A4 EP06802734A EP06802734A EP1934614A4 EP 1934614 A4 EP1934614 A4 EP 1934614A4 EP 06802734 A EP06802734 A EP 06802734A EP 06802734 A EP06802734 A EP 06802734A EP 1934614 A4 EP1934614 A4 EP 1934614A4
Authority
EP
European Patent Office
Prior art keywords
reagents
detection
signaling pathways
protein phosphorylation
carcinoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06802734A
Other languages
German (de)
French (fr)
Other versions
EP1934614A2 (en
Inventor
Roberto Polakiewicz
Kimberly Lee
Charles Farnsworth
Ailan Guo
Klarisa Rikova
Yu Li
Albrecht Moritz
Erik Spek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Signaling Technology Inc
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Publication of EP1934614A2 publication Critical patent/EP1934614A2/en
Publication of EP1934614A4 publication Critical patent/EP1934614A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
EP06802734A 2005-08-31 2006-08-31 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways Withdrawn EP1934614A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71299705P 2005-08-31 2005-08-31
PCT/US2006/034063 WO2007027916A2 (en) 2005-08-31 2006-08-31 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Publications (2)

Publication Number Publication Date
EP1934614A2 EP1934614A2 (en) 2008-06-25
EP1934614A4 true EP1934614A4 (en) 2010-08-04

Family

ID=37809521

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06802734A Withdrawn EP1934614A4 (en) 2005-08-31 2006-08-31 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Country Status (2)

Country Link
EP (1) EP1934614A4 (en)
WO (1) WO2007027916A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024042077A1 (en) 2022-08-25 2024-02-29 Indivumed Gmbh Method for predicting the response to an inhibitor of egfr kinase activity

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030044848A1 (en) * 1998-09-04 2003-03-06 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
WO2004055519A2 (en) * 2002-12-17 2004-07-01 Sinogenomax Co. Ltd. Specific markers for pancreatic cancer
US6924361B1 (en) * 1993-11-02 2005-08-02 Phosphoproteomics Llc Phosphopeptide-specific antibodies that are activity specific; methods of production and antibody uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6924361B1 (en) * 1993-11-02 2005-08-02 Phosphoproteomics Llc Phosphopeptide-specific antibodies that are activity specific; methods of production and antibody uses
US20030044848A1 (en) * 1998-09-04 2003-03-06 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
WO2004055519A2 (en) * 2002-12-17 2004-07-01 Sinogenomax Co. Ltd. Specific markers for pancreatic cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JAWHARI AIDA U ET AL: "Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro.", AMERICAN JOURNAL OF PATHOLOGY, vol. 162, no. 1, January 2003 (2003-01-01), pages 69 - 80, XP002587645, ISSN: 0002-9440 *
ONO SHOICHIRO ET AL: "Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 4, 1997, pages 2527 - 2533, XP002587646, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO2007027916A9 (en) 2009-04-30
EP1934614A2 (en) 2008-06-25
WO2007027916A2 (en) 2007-03-08

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Legal Events

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AX Request for extension of the european patent

Extension state: AL BA HR MK RS

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SPEK, ERIK

Inventor name: MORITZ, ALBRECHT

Inventor name: LI, YU

Inventor name: RIKOVA, KLARISA

Inventor name: GUO, AILAN

Inventor name: FARNSWORTH, CHARLES

Inventor name: LEE, KIMBERLY

Inventor name: POLAKIEWICZ, ROBERTO

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/395 20060101ALI20090525BHEP

Ipc: G01N 33/53 20060101ALI20090525BHEP

Ipc: C12Q 1/00 20060101ALI20090525BHEP

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