EP1872134A4 - Reagents for the detection of protein phosphorylation in carcinoma signaling pathways - Google Patents

Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Info

Publication number
EP1872134A4
EP1872134A4 EP06739581A EP06739581A EP1872134A4 EP 1872134 A4 EP1872134 A4 EP 1872134A4 EP 06739581 A EP06739581 A EP 06739581A EP 06739581 A EP06739581 A EP 06739581A EP 1872134 A4 EP1872134 A4 EP 1872134A4
Authority
EP
European Patent Office
Prior art keywords
reagents
detection
signaling pathways
protein phosphorylation
carcinoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06739581A
Other languages
German (de)
French (fr)
Other versions
EP1872134A2 (en
Inventor
Ailan Guo
Klarisa Rikova
Albrecht Moritz
Yu Li
Charles Farnsworth
Kimberly Lee
Roberto Polakiewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Signaling Technology Inc
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Publication of EP1872134A2 publication Critical patent/EP1872134A2/en
Publication of EP1872134A4 publication Critical patent/EP1872134A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
EP06739581A 2005-04-12 2006-03-24 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways Withdrawn EP1872134A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67044705P 2005-04-12 2005-04-12
PCT/US2006/010868 WO2006113050A2 (en) 2005-04-12 2006-03-24 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Publications (2)

Publication Number Publication Date
EP1872134A2 EP1872134A2 (en) 2008-01-02
EP1872134A4 true EP1872134A4 (en) 2010-09-01

Family

ID=37115632

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06739581A Withdrawn EP1872134A4 (en) 2005-04-12 2006-03-24 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Country Status (2)

Country Link
EP (1) EP1872134A4 (en)
WO (1) WO2006113050A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8242083B2 (en) * 2008-06-23 2012-08-14 Perkinelmer Health Sciences, Inc. Kinase substrates
CN111116734A (en) * 2019-12-23 2020-05-08 维塔恩(广州)医药有限公司 Tumor-associated gene c-kit mutation-associated antigen short peptide and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021230A1 (en) * 1992-04-10 1993-10-28 Dana-Farber Cancer Institute, Inc. Activation-state-specific phosphoprotein immunodetection
WO2002081638A2 (en) * 2001-04-06 2002-10-17 Origene Technologies, Inc Prostate cancer expression profiles
US20030108888A1 (en) * 2001-05-15 2003-06-12 Ludwig Institute For Cancer Research Breast cancer antigens

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021230A1 (en) * 1992-04-10 1993-10-28 Dana-Farber Cancer Institute, Inc. Activation-state-specific phosphoprotein immunodetection
WO2002081638A2 (en) * 2001-04-06 2002-10-17 Origene Technologies, Inc Prostate cancer expression profiles
US20030108888A1 (en) * 2001-05-15 2003-06-12 Ludwig Institute For Cancer Research Breast cancer antigens

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AMAR L S ET AL: "Involvement of desmoplakin phosphorylation in the regulation of desmosomes by protein kinase C, in HeLa cells.", CELL ADHESION AND COMMUNICATION 1999 LNKD- PUBMED:10427965, vol. 7, no. 2, 1999, pages 125 - 138, XP008124497, ISSN: 1061-5385 *
CELL SIGNALING TECHNOLOGY: "PHospho-Tyrosine MOuse mAb (P-Tyr-100)", 1 January 2005 (2005-01-01), XP002592671, Retrieved from the Internet <URL:http://www.cellsignal.com/pdf/9411.pdf> [retrieved on 20100719] *
KANNER S B: "MONOCLONAL ANTIBODIES TO INDIVIDUAL TYROSINE-PHOSPHORYLATED PROTEIN SUBSTRATES OF ONCOGENE-ENCODED TYROSINE KINASES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES (PNAS), NATIONAL ACADEMY OF SCIENCE, US LNKD- DOI:10.1073/PNAS.87.9.3328, vol. 87, no. 9, 1 May 1990 (1990-05-01), pages 3328 - 3332, XP002002168, ISSN: 0027-8424 *
MANDELL J W: "Phosphorylation state-specific antibodies: applications in investigative and diagnostic pathology", AMERICAN JOURNAL OF PATHOLOGY, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY, US, vol. 163, no. 5, 1 November 2003 (2003-11-01), pages 1687 - 1698, XP003017035, ISSN: 0002-9440 *
RUSH J ET AL: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US LNKD- DOI:10.1038/NBT1046, vol. 23, no. 1, 1 January 2005 (2005-01-01), pages 94 - 101, XP002322741, ISSN: 1087-0156 *

Also Published As

Publication number Publication date
WO2006113050A4 (en) 2009-03-26
WO2006113050A3 (en) 2008-12-24
EP1872134A2 (en) 2008-01-02
WO2006113050A8 (en) 2007-12-27
WO2006113050A2 (en) 2006-10-26

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Inventor name: POLAKIEWICZ, ROBERTO

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