EP1931987A4 - Neue verbesserte verfahren zum testen und screening von wirkstoffen unter verwendung von menschlichem gewebe - Google Patents

Neue verbesserte verfahren zum testen und screening von wirkstoffen unter verwendung von menschlichem gewebe

Info

Publication number
EP1931987A4
EP1931987A4 EP06802349A EP06802349A EP1931987A4 EP 1931987 A4 EP1931987 A4 EP 1931987A4 EP 06802349 A EP06802349 A EP 06802349A EP 06802349 A EP06802349 A EP 06802349A EP 1931987 A4 EP1931987 A4 EP 1931987A4
Authority
EP
European Patent Office
Prior art keywords
screening
human tissue
drug testing
novel enhanced
enhanced processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06802349A
Other languages
English (en)
French (fr)
Other versions
EP1931987A1 (de
Inventor
Sung-Soo Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HepaHope Inc
Original Assignee
HepaHope Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/210,511 external-priority patent/US7829325B2/en
Priority claimed from US11/466,730 external-priority patent/US20070048732A1/en
Application filed by HepaHope Inc filed Critical HepaHope Inc
Publication of EP1931987A1 publication Critical patent/EP1931987A1/de
Publication of EP1931987A4 publication Critical patent/EP1931987A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP06802349A 2005-08-24 2006-08-24 Neue verbesserte verfahren zum testen und screening von wirkstoffen unter verwendung von menschlichem gewebe Withdrawn EP1931987A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/210,511 US7829325B2 (en) 2003-12-16 2005-08-24 Drug testing with bio-artificial organ slices including for example those derived from liver
US11/466,730 US20070048732A1 (en) 2005-08-30 2006-08-23 Chemosensitivity tester
PCT/US2006/033262 WO2007025153A1 (en) 2005-08-24 2006-08-24 Novel enhanced processes for drug testing and screening using human tissue

Publications (2)

Publication Number Publication Date
EP1931987A1 EP1931987A1 (de) 2008-06-18
EP1931987A4 true EP1931987A4 (de) 2009-03-18

Family

ID=37771945

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06802349A Withdrawn EP1931987A4 (de) 2005-08-24 2006-08-24 Neue verbesserte verfahren zum testen und screening von wirkstoffen unter verwendung von menschlichem gewebe

Country Status (6)

Country Link
EP (1) EP1931987A4 (de)
AU (1) AU2006282872A1 (de)
BR (1) BRPI0615485A2 (de)
CA (1) CA2620215A1 (de)
IL (1) IL189673A0 (de)
WO (1) WO2007025153A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7797661B2 (en) 2004-09-03 2010-09-14 Abb Research Ag Method and apparatus for describing and managing properties of a transformer coil

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
US5932459A (en) * 1995-10-20 1999-08-03 Sittinger; Michael Artificial tissues, methods for the production and the use thereof
DE19912798C1 (de) * 1999-03-10 2000-02-17 Andreas Jordan Verfahren zur Kultivierung von Krebszellen aus Humangewebe und Vorrichtung zur Aufbereitung von Gewebeproben
JP2002233361A (ja) * 2001-02-06 2002-08-20 Ueda Seni Kagaku Shinkokai トリミング型ゲルを用いた肝組織切片培養法
US20040185558A1 (en) * 2003-01-30 2004-09-23 Corinne Griguer Method for culturing brain tissue in three dimensions
US6852505B1 (en) * 2003-10-15 2005-02-08 Chau-Ting Yeh Hepatitis
US20050130254A1 (en) * 2003-12-16 2005-06-16 Park Sung-Soo Drug testing system with bio-artificial liver

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976870A (en) * 1994-11-09 1999-11-02 Park; Sung-Su Artificial liver composed of a liver-slice culture apparatus
JPH08163996A (ja) * 1994-12-13 1996-06-25 Sumitomo Bakelite Co Ltd 動物細胞毒性試験方法
US20040265997A1 (en) * 2003-06-27 2004-12-30 Park Sung-Soo Bio-artificial liver system

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
US5932459A (en) * 1995-10-20 1999-08-03 Sittinger; Michael Artificial tissues, methods for the production and the use thereof
DE19912798C1 (de) * 1999-03-10 2000-02-17 Andreas Jordan Verfahren zur Kultivierung von Krebszellen aus Humangewebe und Vorrichtung zur Aufbereitung von Gewebeproben
JP2002233361A (ja) * 2001-02-06 2002-08-20 Ueda Seni Kagaku Shinkokai トリミング型ゲルを用いた肝組織切片培養法
US20040185558A1 (en) * 2003-01-30 2004-09-23 Corinne Griguer Method for culturing brain tissue in three dimensions
US6852505B1 (en) * 2003-10-15 2005-02-08 Chau-Ting Yeh Hepatitis
US20050130254A1 (en) * 2003-12-16 2005-06-16 Park Sung-Soo Drug testing system with bio-artificial liver

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FARKAS DORA ET AL: "In vitro methods to study chemically-induced hepatotoxicity: A literature review", CURRENT DRUG METABOLISM, vol. 6, no. 2, April 2005 (2005-04-01), pages 111 - 125, XP008094939, ISSN: 1389-2002 *
See also references of WO2007025153A1 *

Also Published As

Publication number Publication date
WO2007025153A1 (en) 2007-03-01
EP1931987A1 (de) 2008-06-18
IL189673A0 (en) 2008-06-05
AU2006282872A1 (en) 2007-03-01
BRPI0615485A2 (pt) 2016-09-20
CA2620215A1 (en) 2007-03-01

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