EP1919479A4 - Melanocortin receptor-specific piperazine and keto-piperazine compounds - Google Patents

Melanocortin receptor-specific piperazine and keto-piperazine compounds

Info

Publication number
EP1919479A4
EP1919479A4 EP06813394A EP06813394A EP1919479A4 EP 1919479 A4 EP1919479 A4 EP 1919479A4 EP 06813394 A EP06813394 A EP 06813394A EP 06813394 A EP06813394 A EP 06813394A EP 1919479 A4 EP1919479 A4 EP 1919479A4
Authority
EP
European Patent Office
Prior art keywords
piperazine
keto
specific
melanocortin receptor
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06813394A
Other languages
German (de)
French (fr)
Other versions
EP1919479A2 (en
Inventor
Shubh D Sharma
Yi-Qun Shi
Kevin Burris
Zhijun Wu
Papireddy Purma
Yadi Reddy Bonuga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Palatin Technologies Inc
Original Assignee
Palatin Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palatin Technologies Inc filed Critical Palatin Technologies Inc
Publication of EP1919479A2 publication Critical patent/EP1919479A2/en
Publication of EP1919479A4 publication Critical patent/EP1919479A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP06813394A 2005-08-11 2006-08-11 Melanocortin receptor-specific piperazine and keto-piperazine compounds Withdrawn EP1919479A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70748805P 2005-08-11 2005-08-11
PCT/US2006/031474 WO2007021991A2 (en) 2005-08-11 2006-08-11 Melanocortin receptor-specific piperazine and keto-piperazine compounds

Publications (2)

Publication Number Publication Date
EP1919479A2 EP1919479A2 (en) 2008-05-14
EP1919479A4 true EP1919479A4 (en) 2010-11-17

Family

ID=37758229

Family Applications (2)

Application Number Title Priority Date Filing Date
EP06813393A Withdrawn EP1922072A4 (en) 2005-08-11 2006-08-11 Melanocortin receptor-specific piperazine compounds with diamine groups
EP06813394A Withdrawn EP1919479A4 (en) 2005-08-11 2006-08-11 Melanocortin receptor-specific piperazine and keto-piperazine compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP06813393A Withdrawn EP1922072A4 (en) 2005-08-11 2006-08-11 Melanocortin receptor-specific piperazine compounds with diamine groups

Country Status (4)

Country Link
EP (2) EP1922072A4 (en)
JP (2) JP2009504672A (en)
CN (2) CN101272788A (en)
WO (2) WO2007021990A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
CN101272788A (en) * 2005-08-11 2008-09-24 帕拉坦技术公司 Melanocortin receptor-specific piperazine compounds with diamine groups
WO2008090357A2 (en) * 2007-01-24 2008-07-31 Palatin Technologies, Inc. N, n; -substituted piperazines binding to melanocortin receptor
WO2009144432A1 (en) * 2008-05-30 2009-12-03 Palatin Technologies, Inc. Mc4-r agonists for the treatment of obesity
JP6837004B2 (en) * 2015-11-27 2021-03-03 田辺三菱製薬株式会社 Use as a novel imidazole compound and melanocortin receptor agonist

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040157264A1 (en) * 2001-08-10 2004-08-12 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US20050130988A1 (en) * 2001-08-10 2005-06-16 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7456184B2 (en) * 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
WO2004078717A1 (en) * 2003-03-03 2004-09-16 Merck & Co., Inc. Acylated piperazine derivatives as melanocortin-4 receptor agonists
CN101272788A (en) * 2005-08-11 2008-09-24 帕拉坦技术公司 Melanocortin receptor-specific piperazine compounds with diamine groups

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040157264A1 (en) * 2001-08-10 2004-08-12 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US20050130988A1 (en) * 2001-08-10 2005-06-16 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule

Also Published As

Publication number Publication date
CN101272789A (en) 2008-09-24
WO2007021990A3 (en) 2007-08-09
WO2007021991A2 (en) 2007-02-22
EP1919479A2 (en) 2008-05-14
WO2007021991A3 (en) 2007-07-12
EP1922072A4 (en) 2010-12-29
JP2009504671A (en) 2009-02-05
WO2007021990A2 (en) 2007-02-22
CN101272788A (en) 2008-09-24
EP1922072A2 (en) 2008-05-21
JP2009504672A (en) 2009-02-05

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