EP1911432A1 - Mischvorrichtung - Google Patents
Mischvorrichtung Download PDFInfo
- Publication number
- EP1911432A1 EP1911432A1 EP20060122020 EP06122020A EP1911432A1 EP 1911432 A1 EP1911432 A1 EP 1911432A1 EP 20060122020 EP20060122020 EP 20060122020 EP 06122020 A EP06122020 A EP 06122020A EP 1911432 A1 EP1911432 A1 EP 1911432A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- vial
- reservoir
- spike
- liquid
- mixing unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2055—Connecting means having gripping means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2065—Connecting means having aligning and guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
Definitions
- the present invention relates to a mixing unit for reconstituting a dry drug. More particularly, the present invention relates to such a mixing unit which is suitable for being operated using one hand only.
- a drug in dry form, such as lyophilized form. This may, e.g., be in order to reduce degradation of the drug during storage. In this case it is, however, necessary to reconstitute the drug before it is delivered to a person, i.e. it is necessary to mix the lyophilized drug with a liquid, thereby forming a liquid drug.
- This is normally done by means of an ordinary syringe with an ordinary needle. Liquid is sucked into the syringe, the needle is then inserted in a vial containing the lyophilized drug to be reconstituted, and the liquid is forced from the syringe into the vial by means of a movable piston of the syringe.
- the movable piston When the lyophilized drug has been properly reconstituted, the movable piston is pulled out, and the reconstituted drug is thereby retrieved to the syringe.
- the reconstituted drug may subsequently be delivered from the syringe to a person.
- US 2002/0022804 discloses a syringe device comprising a barrel having inner walls defining a compartment in the barrel, a closable nozzle at the base of the barrel and a plunger movable longitudinally within the barrel compartment.
- the plunger has inner walls defining a chamber suitable to receive a vial.
- a hollow needle extends through the plunger to enable fluid communication between the plunger chamber and barrel compartment.
- a compressible and puncturable sealing element within the plunger chamber provides a sterile seal for the needle and barrel compartment.
- US 3,330,280 discloses a syringe in which liquid and powder can be stored and mixed immediately before use. It comprises a hollow vial adapted to contain a medicament in liquid or powder form, a syringe barrel which may also contain liquid, a stopper separating the two and means for communicating the vial and the barrel when desired.
- a mixing unit for mixing dry drug with liquid comprising;
- the first and second housing part is preferably positioned inside each other so that one part can slide telescopically into the other part.
- the first part is preferably closed in the end opposite to the second housing part, the vial being positioned in that end of the first part.
- the first part may be openable in this end so that the vial may be interchanged with a new vial, when it has been used.
- the second housing part is openable in the end opposite the first part, so that the user can get access to the internal of the unit and in particular to the liquid outlet.
- This end is preferably closed by a removable cover, which together with a seal defines a sealed closure of the unit.
- the cover may stay attached to the unit after having been removed in order to leave the user with less pieces of waste material as possible.
- the reservoir may be any suitable kind of reservoir, such as a cartridge, a syringe, a flexible reservoir, e.g. a bag, forming part of the unit.
- the liquid contained in the reservoir is preferably a solvent liquid being suitable for reconstitution of a lyophilized drug contained in the vial.
- the amount and kind of liquid in the reservoir is preferably chosen in such a manner that it matches a specific lyophilized drug. Thereby it is ensured, that when a vial containing that specific lyophilized drug is positioned in the vial adapter, the lyophilized drug is reconstituted correctly and in a suitable manner.
- the intermediate part provided inside the housing parts comprises a first spike being adapted to penetrate a septum of the vial, and a second spike adapted to penetrate a septum of the reservoir.
- the vial is positioned adjacent the first spike and the reservoir is positioned on the opposite side of the intermediate part adjacent the second spike.
- the intermediate part preferably comprises a vial adapter for receiving and retaining the vial in a fixed position in relation to the first spike, and a reservoir adapter for receiving and retaining the reservoir in a fixed position in relation to the second spike when the first and second housing parts are moved towards each other.
- the adapters are preferably shaped in such a manner that a vial and reservoir is positioned there in a manner which substantially fixes them relatively in the intermediate part.
- the adapters may comprise means for gripping a part of the vial and reservoir, e.g. a neck or shoulder part thereof.
- the flexibility of the gripping means of the vial adapter is preferably greater than the flexibility of the gripping means of the reservoir adapter resulting in the vial adapter receiving and retaining the vial before the reservoir adapter receives and retains the reservoir when moving the first and second housing parts towards each other. This is to ensure that the first spike penetrates the vial before the second spike penetrates the reservoir.
- the first and second spike is hollow spikes, the hollow part thereby giving access to the interior of the vial and reservoir, respectively, once the spikes have penetrated the septum, respectively.
- the first and second spikes may advantageously form part of a double pointed hollow needle establishing a fluid connection between the reservoir and the vial.
- the fluid connection is established between the reservoir and the vial by moving the first and second housing part towards each other.
- the first spike is preferably longer than the second spike, so that the first spike is adapted to penetrate the septum of the vial before the second spike penetrates the septum of the reservoir, when moving the first and second housing parts towards each other.
- the piston (or plunger) is positioned in the reservoir in such a manner that the liquid is forced out of the reservoir, via the established fluid connection provided by the spikes, when the piston is moved in a specified direction.
- the piston is preferably in connection with a part of the second housing part, or a part of the above mentioned cover and by pressing the second housing part towards the first housing part, the piston is forced in said specified direction forcing liquid from the reservoir into the vial.
- the piston comprises a liquid channel for connecting a liquid outlet of the unit with the internal of the vial via the established fluid connection.
- the liquid outlet preferably forms an end of the channel, and the outlet may be adapted for connection to an infusion device, such as a syringe.
- the outlet may e.g. be a Luer-lock connection.
- the channel is preferably sealed by a membrane to make sure that drug or liquid does not enter the channel, while the piston is moved.
- the membrane is preferably adapted to be penetrated by the second spike, when the piston reaches its end position in the reservoir.
- the unit preferably comprises locking means for locking the first housing part in relation to the second housing part, when the piston has reached an end position in which the liquid has been forced into the vial.
- the first and second housing parts are preferably guided in relation to each other by slots, and the locking means may be provided by a "snap-lock" provided in said slots.
- the "snap-lock” may e.g. by a loaded tap that enters a groove or hole in the slot, when the second part reaches an end position in relation to the first part.
- the second spike may comprise two separate channels; a first channel defining said fluid connection in combination with the first spike, and a second channel defining a fluid connection between the internal of the vial and an air outlet for equalising pressure provided in the vial.
- the second channel preferably comprises a filter being air permeable, but not liquid permeable.
- air from the vial may escape as liquid is forced from the reservoir into the vial.
- the pressure in the vial is equalized as the liquid enters the vial.
- the pressure equalization may be obtained by use of a unidirectional valve allowing passage of, e.g., air or liquid in a direction out of the vial, but preventing such passage in a direction into the vial.
- At least the first and second housing part, the intermediate part, the reservoir, the piston and the vial forms a substantial integral unit.
- the term 'integral unit' should be interpreted to mean a unit which is manufactured and operated as one unit.
- these parts may be delivered as an 'all-in-one' and/or a 'ready-to-use' package which is easy to operate.
- it is only necessary to operate the first and second housing part in relation to each other which results in establishment of a fluid connection and forcing of the liquid from the reservoir to the vial.
- it is ensured that the amount and kind of liquid in the reservoir matches the lyophilized drug of a specific kind of vial. Thereby the risk of incorrect reconstitution of the drug is reduced.
- the drug is reconstituted, the user can easily get access to the drug via the channel provided in the piston, which is very convenient.
- the pieces of waste material is reduced to a minimum, as the user only needs to remove the cover to get access to the drug and does not need to disassemble the unit and/or remove the vial or reservoir from the unit before getting access to the reconstituted drug.
- the mixing unit according to the invention provides i.a. the following advantages; the number of steps needed to be performed by the user is reduced, the risk of contamination is reduced, the risk of incorrect reconstitution and dosage is reduced, and the unit is easy to operate, e.g. using just one hand.
- a mixing unit comprising:
- the unit according to this aspect may comprise any of the features and elements mentioned in connection with the first mentioned aspect of the invention.
- Fig. 1 is a cross-sectional view of a mixing unit according to an embodiment of the invention
- Fig. 2 is a perspective view of a mixing unit according to another embodiment of the invention.
- Fig. 1 is a cross-sectional view of a mixing unit 1 according to an embodiment of the invention.
- the unit 1 comprises a first housing part 2 and a second housing part 3 which are connected to each other so that they can move telescopically into each other.
- the first housing part 2 has a closed end in which a vial 5 containing dry drug 4 is positioned.
- a reservoir 6 in the form of a cartridge is positioned opposite to the vial 5 and contains liquid 7 to be mixed with the drug 4.
- An intermediate part 8 is provided between the vial 5 and reservoir 6 for establishing fluid connection there between.
- the intermediate part 8 comprises a vial adapter 9 for receiving and retaining the neck of the vial 5 when the first and second housing parts are moved towards each other.
- the vial adapter 9 comprises a first spike 10 adapted to penetrate a septum 11 of the vial.
- the intermediate part 8 further comprises a reservoir adapter 12 for receiving and retaining the neck of the cartridge 6.
- a second spike 13 with one channel 13a at the reservoir adapter is adapted to penetrate the septum 14 of the cartridge 6.
- a piston 15 is movable inside the cartridge 6 in a downwards direction and is forced downwards by means of the part 16 of the second housing part 3 abutting the piston, when the two housing parts are moved towards each other. Thereby the piston 15 forces liquid 7 from the cartridge 6 through the hollow parts of the spikes 10, 13 and into the vial 5. Thereby the lyophilized drug in the vial 5 is reconstituted.
- the adapters flex outwards in order to grip around the neck.
- the vial adapter 9 is made more flexible than the reservoir adapter and the first spike 10 is made longer than the second spike 13.
- the first housing part 2 has guide slots 17 provided inside, which guides the two housing parts in relation to each other, and the slots 17 further comprise a hole or groove 18 in which the "snap-lock" 19 enters when the second part 3 has reached an end position. Thereby, the two housing parts are interlocked.
- the first spike 10 has two channels 20, 21; one channel 20 forming part of the fluid connection between the cartridge and vial, and one channel 21 acting as a pressure equalizing outlet. Thereby, the air in the vial can escape through channel 21 when liquid enters the vial.
- the channel comprises a filter 22 which is permeable to air but not to liquid.
- the channel 21 extends further into the vial than the channel 20, which ensures that the air, that is sucked back into the vial as the vial is being emptied, is not sucked around and into the spike 10.
- the piston 15 comprises a liquid channel 23 for connecting a liquid outlet 24 with the internal of the vial 5 via the established fluid connection 10, 13.
- a membrane 25 ensures that liquid is not entering the channel during pressing the piston 15 downwards. When the piston reaches an end position, the membrane 25 is penetrated by the second spike 13, and an open liquid channel 23 is provided between the vial and the outlet 24.
- the second housing part 3 is closed by a removable cover 26 having a seal 27. After having removed the cover 26, the outlet 24 can be connected to a syringe, and the reconstituted drug can be sucked out from the vial 5 via the channel 24 and the fluid connection 10, 13.
- the unit functions as follows;
- the membrane 25 could be substituted by a valve system that opens when a syringe or any other infusion device is connected to the outlet.
- FIG. 2 is a perspective view of a mixing unit 1 according to another embodiment of the invention.
- a housing part 2 contains a vial 5 with dry drug 4, an intermediate part 8 having a vial adapter 9 with a spike 10 to penetrate the septum 11.
- a piston 15 closes a reservoir 6 containing liquid 7, and the piston 15 comprises a liquid channel 23 through which the liquid is forced into the vial.
- the spike 10 first penetrates a rubber stopper 29 placed over the spike and then the septum 11 of the vial.
- the fluid connection is now established, and the liquid is forced into the vial by pressing the vial and thus the piston further downwards, and the drug will be reconstituted.
- the piston 15 is now in an end position (not shown) and a sealing 30 provided in the bottom of the reservoir is penetrated by a spike 31 on a syringe connector 32, and a liquid channel is provided between the vial and the syringe 33.
- This unit is not closed in one end, which allows for pooling of vials, as the vial can be changed with a new one.
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20060122020 EP1911432A1 (de) | 2006-10-10 | 2006-10-10 | Mischvorrichtung |
PCT/EP2007/051439 WO2007101772A1 (en) | 2006-03-07 | 2007-02-14 | A drug mixing device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20060122020 EP1911432A1 (de) | 2006-10-10 | 2006-10-10 | Mischvorrichtung |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1911432A1 true EP1911432A1 (de) | 2008-04-16 |
Family
ID=37763955
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20060122020 Withdrawn EP1911432A1 (de) | 2006-03-07 | 2006-10-10 | Mischvorrichtung |
Country Status (1)
Country | Link |
---|---|
EP (1) | EP1911432A1 (de) |
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010078651A1 (en) * | 2009-01-09 | 2010-07-15 | Duoject Medical Systems Inc. | Fluid transfer device |
CN102596145A (zh) * | 2009-10-30 | 2012-07-18 | 杜杰克特医疗系统有限公司 | 瓶间转移系统 |
WO2014181328A1 (en) * | 2013-05-10 | 2014-11-13 | Medimop Medical Projects Ltd | Medical devices including vial adapter with inline dry drug module |
US8979792B2 (en) | 2009-11-12 | 2015-03-17 | Medimop Medical Projects Ltd. | Inline liquid drug medical devices with linear displaceable sliding flow control member |
US8998875B2 (en) | 2009-10-01 | 2015-04-07 | Medimop Medical Projects Ltd. | Vial assemblage with vial and pre-attached fluid transfer device |
USD734868S1 (en) | 2012-11-27 | 2015-07-21 | Medimop Medical Projects Ltd. | Drug vial adapter with downwardly depending stopper |
USD737436S1 (en) | 2012-02-13 | 2015-08-25 | Medimop Medical Projects Ltd. | Liquid drug reconstitution assembly |
US9283324B2 (en) | 2012-04-05 | 2016-03-15 | Medimop Medical Projects, Ltd | Fluid transfer devices having cartridge port with cartridge ejection arrangement |
US9339438B2 (en) | 2012-09-13 | 2016-05-17 | Medimop Medical Projects Ltd. | Telescopic female drug vial adapter |
USD757933S1 (en) | 2014-09-11 | 2016-05-31 | Medimop Medical Projects Ltd. | Dual vial adapter assemblage |
USD765837S1 (en) | 2013-08-07 | 2016-09-06 | Medimop Medical Projects Ltd. | Liquid transfer device with integral vial adapter |
USD767124S1 (en) | 2013-08-07 | 2016-09-20 | Medimop Medical Projects Ltd. | Liquid transfer device with integral vial adapter |
US9795536B2 (en) | 2012-08-26 | 2017-10-24 | Medimop Medical Projects, Ltd. | Liquid drug transfer devices employing manual rotation for dual flow communication step actuations |
US9801786B2 (en) | 2013-04-14 | 2017-10-31 | Medimop Medical Projects Ltd. | Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe |
USD801522S1 (en) | 2015-11-09 | 2017-10-31 | Medimop Medical Projects Ltd. | Fluid transfer assembly |
US9839580B2 (en) | 2012-08-26 | 2017-12-12 | Medimop Medical Projects, Ltd. | Liquid drug transfer devices |
US10278897B2 (en) | 2015-11-25 | 2019-05-07 | West Pharma. Services IL, Ltd. | Dual vial adapter assemblage including drug vial adapter with self-sealing access valve |
US10285907B2 (en) | 2015-01-05 | 2019-05-14 | West Pharma. Services IL, Ltd. | Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage |
US10357429B2 (en) | 2015-07-16 | 2019-07-23 | West Pharma. Services IL, Ltd. | Liquid drug transfer devices for secure telescopic snap fit on injection vials |
US10646404B2 (en) | 2016-05-24 | 2020-05-12 | West Pharma. Services IL, Ltd. | Dual vial adapter assemblages including identical twin vial adapters |
US10688295B2 (en) | 2013-08-07 | 2020-06-23 | West Pharma. Services IL, Ltd. | Liquid transfer devices for use with infusion liquid containers |
US10765604B2 (en) | 2016-05-24 | 2020-09-08 | West Pharma. Services IL, Ltd. | Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter |
US10772797B2 (en) | 2016-12-06 | 2020-09-15 | West Pharma. Services IL, Ltd. | Liquid drug transfer devices for use with intact discrete injection vial release tool |
US10806671B2 (en) | 2016-08-21 | 2020-10-20 | West Pharma. Services IL, Ltd. | Syringe assembly |
US10806667B2 (en) | 2016-06-06 | 2020-10-20 | West Pharma. Services IL, Ltd. | Fluid transfer devices for filling drug pump cartridges with liquid drug contents |
US10945921B2 (en) | 2017-03-29 | 2021-03-16 | West Pharma. Services IL, Ltd. | User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages |
USD917693S1 (en) | 2018-07-06 | 2021-04-27 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
IT201900020108A1 (it) * | 2019-10-30 | 2021-04-30 | Bormioli Pharma Spa | Miscelatore monouso con prelievo tramite siringa |
USD923782S1 (en) | 2019-01-17 | 2021-06-29 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
USD923812S1 (en) | 2019-01-16 | 2021-06-29 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
USD954253S1 (en) | 2019-04-30 | 2022-06-07 | West Pharma. Services IL, Ltd. | Liquid transfer device |
USD956958S1 (en) | 2020-07-13 | 2022-07-05 | West Pharma. Services IL, Ltd. | Liquid transfer device |
US11642285B2 (en) | 2017-09-29 | 2023-05-09 | West Pharma. Services IL, Ltd. | Dual vial adapter assemblages including twin vented female vial adapters |
US11918542B2 (en) | 2019-01-31 | 2024-03-05 | West Pharma. Services IL, Ltd. | Liquid transfer device |
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US6746438B1 (en) * | 1999-03-18 | 2004-06-08 | Sedat | Device for two-way transfer of a liquid between a bottle and a cartridge |
US20060030832A1 (en) * | 2000-01-24 | 2006-02-09 | Bracco Diagnostics, Inc. | Tabletop drug dispensing vial access adapter |
-
2006
- 2006-10-10 EP EP20060122020 patent/EP1911432A1/de not_active Withdrawn
Patent Citations (3)
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US5281198A (en) * | 1992-05-04 | 1994-01-25 | Habley Medical Technology Corporation | Pharmaceutical component-mixing delivery assembly |
US6746438B1 (en) * | 1999-03-18 | 2004-06-08 | Sedat | Device for two-way transfer of a liquid between a bottle and a cartridge |
US20060030832A1 (en) * | 2000-01-24 | 2006-02-09 | Bracco Diagnostics, Inc. | Tabletop drug dispensing vial access adapter |
Cited By (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010078651A1 (en) * | 2009-01-09 | 2010-07-15 | Duoject Medical Systems Inc. | Fluid transfer device |
US8998875B2 (en) | 2009-10-01 | 2015-04-07 | Medimop Medical Projects Ltd. | Vial assemblage with vial and pre-attached fluid transfer device |
CN102596145A (zh) * | 2009-10-30 | 2012-07-18 | 杜杰克特医疗系统有限公司 | 瓶间转移系统 |
CN102596145B (zh) * | 2009-10-30 | 2016-08-24 | 杜杰克特医疗系统有限公司 | 瓶间转移系统 |
US9132063B2 (en) | 2009-11-12 | 2015-09-15 | Medimop Medical Projects Ltd. | Inline liquid drug medical devices with linear displaceable sliding flow control member |
US8979792B2 (en) | 2009-11-12 | 2015-03-17 | Medimop Medical Projects Ltd. | Inline liquid drug medical devices with linear displaceable sliding flow control member |
USD737436S1 (en) | 2012-02-13 | 2015-08-25 | Medimop Medical Projects Ltd. | Liquid drug reconstitution assembly |
US9283324B2 (en) | 2012-04-05 | 2016-03-15 | Medimop Medical Projects, Ltd | Fluid transfer devices having cartridge port with cartridge ejection arrangement |
US9795536B2 (en) | 2012-08-26 | 2017-10-24 | Medimop Medical Projects, Ltd. | Liquid drug transfer devices employing manual rotation for dual flow communication step actuations |
US9839580B2 (en) | 2012-08-26 | 2017-12-12 | Medimop Medical Projects, Ltd. | Liquid drug transfer devices |
US10299990B2 (en) | 2012-08-26 | 2019-05-28 | West Pharma. Services IL, Ltd. | Liquid drug transfer devices |
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