EP1910524A4 - Modulation of sphingosine kinase signalling - Google Patents
Modulation of sphingosine kinase signallingInfo
- Publication number
- EP1910524A4 EP1910524A4 EP06752620A EP06752620A EP1910524A4 EP 1910524 A4 EP1910524 A4 EP 1910524A4 EP 06752620 A EP06752620 A EP 06752620A EP 06752620 A EP06752620 A EP 06752620A EP 1910524 A4 EP1910524 A4 EP 1910524A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- modulation
- sphingosine kinase
- kinase signalling
- signalling
- sphingosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01091—Sphinganine kinase (2.7.1.91)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2005903257A AU2005903257A0 (en) | 2005-06-21 | A method of modulating enzyme activity and agents for use therein | |
PCT/AU2006/000866 WO2006135968A1 (en) | 2005-06-21 | 2006-06-21 | Modulation of sphingosine kinase signalling |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1910524A1 EP1910524A1 (en) | 2008-04-16 |
EP1910524A4 true EP1910524A4 (en) | 2009-04-01 |
Family
ID=37570027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06752620A Withdrawn EP1910524A4 (en) | 2005-06-21 | 2006-06-21 | Modulation of sphingosine kinase signalling |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1910524A4 (en) |
JP (1) | JP2008546721A (en) |
CA (1) | CA2612644A1 (en) |
WO (1) | WO2006135968A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8324237B2 (en) | 2005-05-20 | 2012-12-04 | Smith Charles D | Methods for the treatment and prevention of inflammatory diseases |
WO2006135969A1 (en) * | 2005-06-21 | 2006-12-28 | Medvet Science Pty. Ltd. | Modulation of sphingosine kinase signalling |
EP2166094A1 (en) | 2008-09-23 | 2010-03-24 | Ecole Normale Superieure De Lyon | Methods for prolonging the health benefits triggered by a dietary restriction using a sphingosine kinase inhibitor |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085953A1 (en) * | 2000-05-11 | 2001-11-15 | Medvet Science Pty. Ltd. | Sphingosine kinase and uses thereof |
-
2006
- 2006-06-21 EP EP06752620A patent/EP1910524A4/en not_active Withdrawn
- 2006-06-21 JP JP2008517274A patent/JP2008546721A/en not_active Withdrawn
- 2006-06-21 WO PCT/AU2006/000866 patent/WO2006135968A1/en active Application Filing
- 2006-06-21 CA CA002612644A patent/CA2612644A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085953A1 (en) * | 2000-05-11 | 2001-11-15 | Medvet Science Pty. Ltd. | Sphingosine kinase and uses thereof |
Non-Patent Citations (3)
Title |
---|
LECLERCQ TAMARA M ET AL: "Eukaryotic elongation factor 1A interacts with sphingosine kinase and directly enhances its catalytic activity", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, no. 15, April 2008 (2008-04-01), pages 9606 - 9614, XP002510631, ISSN: 0021-9258 * |
See also references of WO2006135968A1 * |
XIA P ET AL: "Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,; US, vol. 277, no. 10, 8 March 2002 (2002-03-08), pages 7996 - 8003, XP002992506, ISSN: 0021-9258 * |
Also Published As
Publication number | Publication date |
---|---|
JP2008546721A (en) | 2008-12-25 |
CA2612644A1 (en) | 2006-12-28 |
WO2006135968A1 (en) | 2006-12-28 |
EP1910524A1 (en) | 2008-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20080121 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
DAX | Request for extension of the european patent (deleted) | ||
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: VADAS, MATHEW, ALEXANDER Inventor name: PITSON, STUART, M. Inventor name: LECLERCQ, TAMARA |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1115334 Country of ref document: HK |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20090227 |
|
17Q | First examination report despatched |
Effective date: 20090623 |
|
R17C | First examination report despatched (corrected) |
Effective date: 20090715 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20100126 |