EP1888741A4 - Treatment of ischemia using stem cells - Google Patents

Treatment of ischemia using stem cells

Info

Publication number
EP1888741A4
EP1888741A4 EP06771203A EP06771203A EP1888741A4 EP 1888741 A4 EP1888741 A4 EP 1888741A4 EP 06771203 A EP06771203 A EP 06771203A EP 06771203 A EP06771203 A EP 06771203A EP 1888741 A4 EP1888741 A4 EP 1888741A4
Authority
EP
European Patent Office
Prior art keywords
ischemia
treatment
stem cells
stem
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06771203A
Other languages
German (de)
French (fr)
Other versions
EP1888741B1 (en
EP1888741A2 (en
Inventor
Andreas Muhs
Stephan Wnendt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ViaCord LLC
Original Assignee
ViaCell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37482164&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1888741(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ViaCell Inc filed Critical ViaCell Inc
Priority to EP13001977.1A priority Critical patent/EP2662439A1/en
Publication of EP1888741A2 publication Critical patent/EP1888741A2/en
Publication of EP1888741A4 publication Critical patent/EP1888741A4/en
Application granted granted Critical
Publication of EP1888741B1 publication Critical patent/EP1888741B1/en
Revoked legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP06771203.4A 2005-05-27 2006-05-26 Treatment of ischemia using stem cells Revoked EP1888741B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP13001977.1A EP2662439A1 (en) 2005-05-27 2006-05-26 Treatment of ischemia using stem cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68561405P 2005-05-27 2005-05-27
PCT/US2006/020290 WO2006130433A2 (en) 2005-05-27 2006-05-26 Treatment of ischemia using stem cells

Publications (3)

Publication Number Publication Date
EP1888741A2 EP1888741A2 (en) 2008-02-20
EP1888741A4 true EP1888741A4 (en) 2011-01-19
EP1888741B1 EP1888741B1 (en) 2013-04-17

Family

ID=37482164

Family Applications (2)

Application Number Title Priority Date Filing Date
EP13001977.1A Withdrawn EP2662439A1 (en) 2005-05-27 2006-05-26 Treatment of ischemia using stem cells
EP06771203.4A Revoked EP1888741B1 (en) 2005-05-27 2006-05-26 Treatment of ischemia using stem cells

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP13001977.1A Withdrawn EP2662439A1 (en) 2005-05-27 2006-05-26 Treatment of ischemia using stem cells

Country Status (4)

Country Link
US (2) US8613906B2 (en)
EP (2) EP2662439A1 (en)
JP (1) JP2008545703A (en)
WO (1) WO2006130433A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070298015A1 (en) * 2004-04-28 2007-12-27 Viacell, Inc. Treatment of Muscular Dystrophy with Mobilized Peripheral Blood Pluripotent Cells
GB0822246D0 (en) 2008-12-05 2009-01-14 Reneuron Ltd Composition
GB0902034D0 (en) 2009-02-06 2009-03-11 Reneuron Ltd Method
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
CN106715676A (en) 2014-09-26 2017-05-24 泰尔茂比司特公司 Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
TWI825446B (en) * 2020-08-14 2023-12-11 中國醫藥大學 Use of medicinal composition for treating tissue ischemia
JP2024511064A (en) 2021-03-23 2024-03-12 テルモ ビーシーティー、インコーポレーテッド Cell capture and proliferation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036751A2 (en) * 2000-11-03 2002-05-10 Kourion Therapeutics Gmbh Human cord blood derived unrestricted somatic stem cells (ussc)
WO2005063303A1 (en) * 2003-12-19 2005-07-14 Viacell, Inc. Use of human cord blood-derived pluripotent cells for the treatment of disease

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5837539A (en) 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6010696A (en) 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
AU4543193A (en) 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
US5804446A (en) 1993-02-26 1998-09-08 The Picower Institute For Medical Research Blood-borne mesenchymal cells
US6054121A (en) 1993-02-26 2000-04-25 The Picower Institute For Medical Research Modulation of immune responses in blood-borne mesenchymal cells
US5654186A (en) 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
US5591625A (en) 1993-11-24 1997-01-07 Case Western Reserve University Transduced mesenchymal stem cells
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US5908782A (en) 1995-06-05 1999-06-01 Osiris Therapeutics, Inc. Chemically defined medium for human mesenchymal stem cells
US5591444A (en) 1995-07-28 1997-01-07 Isolagen Technologies, Inc. Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects
PT868505E (en) 1995-11-16 2005-06-30 Univ Case Western Reserve IN VITRO CONDROGENIC INDUCTION OF HUMAN MESENCHINEAL STAMINA CELLS
US5827740A (en) 1996-07-30 1998-10-27 Osiris Therapeutics, Inc. Adipogenic differentiation of human mesenchymal stem cells
EP0941027A4 (en) 1996-11-15 2000-08-09 Osiris Therapeutics Inc MSC-megakaryocyte precursor composition and method of isolating MSCS associated with isolated megakaryocytes by isolating megakaryocytes
WO1999011287A1 (en) 1997-09-04 1999-03-11 Osiris Therapeutics, Inc. Ligands that modulate differentiation of mesenchymal stem cells
US7811557B1 (en) 2000-10-27 2010-10-12 Viacell, Inc. Methods for improving central nervous system functioning

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036751A2 (en) * 2000-11-03 2002-05-10 Kourion Therapeutics Gmbh Human cord blood derived unrestricted somatic stem cells (ussc)
WO2005063303A1 (en) * 2003-12-19 2005-07-14 Viacell, Inc. Use of human cord blood-derived pluripotent cells for the treatment of disease

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KOGLER G ET AL: "Cytokine production and hematopoiesis supporting activity of cord blood-derived unrestricted somatic stem cells", EXPERIMENTAL HEMATOLOGY, ELSEVIER INC, US, vol. 33, no. 5, 1 May 2005 (2005-05-01), pages 573 - 583, XP004866151, ISSN: 0301-472X, DOI: 10.1016/J.EXPHEM.2005.01.012 *
YANG C ET AL: "ENHANCEMENT OF NEOVASCULARIZATION WITH CORD BLOOD CD133+ CELL-DERIVED ENDOTHELIAL PROGENITOR CELL TRANSPLANTATION", THROMBOSIS AND HAEMOSTASIS, SCHATTAUER GMBH, DE; US, vol. 91, no. 6, 5 April 2004 (2004-04-05), pages 1202 - 1212, XP009056099, ISSN: 0340-6245 *
YANG C: "TRANSPLANTATION OF ENDOTHELIAL PROGENITOR CELLS FROM CORD BLOOD CD133+ CELLS AUGMENTS THE NEOVASCULARIZATION IN MURINE ISCHEMIC LIMB", EXPERIMENTAL HEMATOLOGY, ELSEVIER INC, US, vol. 31, no. 7, SUPPL. 01, 8 July 2003 (2003-07-08), XP009056101, ISSN: 0301-472X *

Also Published As

Publication number Publication date
WO2006130433A2 (en) 2006-12-07
EP2662439A1 (en) 2013-11-13
JP2008545703A (en) 2008-12-18
EP1888741B1 (en) 2013-04-17
EP1888741A2 (en) 2008-02-20
US20140079673A1 (en) 2014-03-20
WO2006130433A3 (en) 2009-04-30
US20090214481A1 (en) 2009-08-27
US8613906B2 (en) 2013-12-24

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