EP1883412A4 - Combination therapy with sulodexide and a blood pressure reducing agent in the treatment of diabetic nephropathy - Google Patents
Combination therapy with sulodexide and a blood pressure reducing agent in the treatment of diabetic nephropathyInfo
- Publication number
- EP1883412A4 EP1883412A4 EP06759150A EP06759150A EP1883412A4 EP 1883412 A4 EP1883412 A4 EP 1883412A4 EP 06759150 A EP06759150 A EP 06759150A EP 06759150 A EP06759150 A EP 06759150A EP 1883412 A4 EP1883412 A4 EP 1883412A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- sulodexide
- treatment
- reducing agent
- blood pressure
- pressure reducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67909605P | 2005-05-05 | 2005-05-05 | |
US73697305P | 2005-11-14 | 2005-11-14 | |
PCT/US2006/017403 WO2006121853A1 (en) | 2005-05-05 | 2006-05-05 | Combination therapy with sulodexide and a blood pressure reducing agent in the treatment of diabetic nephropathy |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1883412A1 EP1883412A1 (en) | 2008-02-06 |
EP1883412A4 true EP1883412A4 (en) | 2008-09-03 |
Family
ID=37396874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06759150A Withdrawn EP1883412A4 (en) | 2005-05-05 | 2006-05-05 | Combination therapy with sulodexide and a blood pressure reducing agent in the treatment of diabetic nephropathy |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1883412A4 (en) |
JP (1) | JP2008540448A (en) |
AU (1) | AU2006244446A1 (en) |
CA (1) | CA2606880A1 (en) |
IL (1) | IL187142A0 (en) |
WO (1) | WO2006121853A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2008008213A (en) | 2005-12-22 | 2008-09-03 | Neurochem Int Ltd | Treatment of renal disorders, diabetic nephopathy and dyslipidemias. |
CN101632686A (en) * | 2008-04-04 | 2010-01-27 | 马斯特里赫特大学 | Use of glycosaminoglycan for restoring glycocalyx |
CN104017102B (en) * | 2014-06-19 | 2016-02-24 | 深圳市海普瑞药业股份有限公司 | Ethanol precipitation prepares the method for Sulodexide raw material from heparin byproduct |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001093850A2 (en) * | 2000-06-07 | 2001-12-13 | Alfa Wassermann, Inc. | Methods and compositions using sulodexide for the treatment of diabetic nephropathy |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1270846B (en) * | 1993-05-10 | 1997-05-13 | Alfa Wassermann Spa | USE OF SULODEXIDE AND MEDICINAL SPECIALTIES THAT CONTAIN IT IN THE TREATMENT OF DIABETIC NEPHROPATHY. |
IT1292426B1 (en) * | 1997-06-27 | 1999-02-08 | Nicox Sa | NITRATED SALTS OF ACE-INHIBITORS |
-
2006
- 2006-05-05 EP EP06759150A patent/EP1883412A4/en not_active Withdrawn
- 2006-05-05 AU AU2006244446A patent/AU2006244446A1/en not_active Abandoned
- 2006-05-05 JP JP2008510255A patent/JP2008540448A/en active Pending
- 2006-05-05 WO PCT/US2006/017403 patent/WO2006121853A1/en active Application Filing
- 2006-05-05 CA CA002606880A patent/CA2606880A1/en not_active Abandoned
-
2007
- 2007-11-04 IL IL187142A patent/IL187142A0/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001093850A2 (en) * | 2000-06-07 | 2001-12-13 | Alfa Wassermann, Inc. | Methods and compositions using sulodexide for the treatment of diabetic nephropathy |
Non-Patent Citations (3)
Title |
---|
CANDIDO RICCARDO ET AL: "Treatment for diabetic nephropathy - a review of the recent patent literature.", IDRUGS : THE INVESTIGATIONAL DRUGS JOURNAL MAR 2002, vol. 5, no. 3, March 2002 (2002-03-01), pages 237 - 265, XP002486359, ISSN: 1369-7056 * |
GAMBARO GIOVANNI ET AL: "Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The Di.N.A.S. randomized trial", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol. 13, no. 6, June 2002 (2002-06-01), pages 1615 - 1625, XP002486358, ISSN: 1046-6673 * |
See also references of WO2006121853A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2606880A1 (en) | 2006-11-16 |
EP1883412A1 (en) | 2008-02-06 |
AU2006244446A1 (en) | 2006-11-16 |
WO2006121853A1 (en) | 2006-11-16 |
JP2008540448A (en) | 2008-11-20 |
IL187142A0 (en) | 2008-06-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL236831A0 (en) | Mirna expression in human peripheral blood microvesicles and uses thereof | |
EP2043705A4 (en) | System and method for use of agent in combination with subatmospheric pressure tissue treatment | |
IL246402A (en) | Therapeutic agent for treating obesity, diabetes and diseases associated with impaired glucose tolerance | |
HUE064811T2 (en) | Exendin for use in treating diabetes and reducing body weight | |
KZ24152B (en) | Method of photosensitizer activation, treatment method with application of activated photosensitizer and photosensitizer application to prepare medicine | |
EP1799263A4 (en) | Reducing er stress in the treatment of obesity and diabetes | |
IL207894A (en) | Therapeutic combination for use in the treatment of a hyperproliferative disorder comprising trastuzumab-mcc-dmi and a chemotherapeutic agent | |
IL186592A0 (en) | Treatment and diagnostic catheters with hydrogel electrodes | |
HK1158705A1 (en) | Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions | |
GB0523576D0 (en) | Drug composition and its use in therapy | |
EP2061531A4 (en) | Intravascular blood pump and catheter | |
PL1912650T3 (en) | Use of flibanserin in the treatment of obesity | |
EP2059183A4 (en) | Energetically activated biomedical nanotheurapeutics integrating dental and medical treatments and procedures | |
EP2046973A4 (en) | For the identification, assessment, and treatment of patients with cancer therapy | |
GB0700436D0 (en) | Impulse therapy for enhanced blood circulation in the body | |
IL190206A0 (en) | Method for lowering blood pressure in pre-hypertensive individuals and/or individuals with metabolic syndrome | |
IL183056A0 (en) | Use of ranolazine in combination with at least one remodeling agent for revering ieft ventricular remodeling in the treatment of heart failure | |
HK1168283A1 (en) | Sorcs1-like agent for use in the treatment of insulin resistance and diseases related thereto sorcs1 | |
EP2086506A4 (en) | Preparation of heavy metal-containing nano-liposomes and their uses in medical therapy | |
IL201426A0 (en) | Drug combination and its use in the treatment of muscle loss | |
EP2046313A4 (en) | The use of naphtoquinones in the treatment and control of diabetes, insulin resistance and hyperglycemia | |
IL187142A0 (en) | Combination therapy with sulodexide and a blood pressure reducing agent in the treatment of diabetic nephropathy | |
GB0821839D0 (en) | The use of metformin and compounds containing metformin in the treatment of diseases or conditions in patients with raised serum amyloid A | |
GB0700911D0 (en) | Treatment of inflammation and the complement and kinin cascades in a patient, particularly in chronic ulcerous skin lesions | |
PT2160213E (en) | Kit for the extracorporeal treatment of a biological fluid of a patient, and unit provided with said kit |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20071119 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK YU |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 13/12 20060101ALI20080722BHEP Ipc: A61K 45/06 20060101ALI20080722BHEP Ipc: A61K 31/41 20060101ALI20080722BHEP Ipc: A61K 31/40 20060101ALI20080722BHEP Ipc: A61K 31/727 20060101ALI20080722BHEP Ipc: A61K 31/737 20060101AFI20061201BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20080731 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20081030 |