EP1853906A4 - Method and apparatus for sample deposition - Google Patents

Method and apparatus for sample deposition

Info

Publication number
EP1853906A4
EP1853906A4 EP06705124A EP06705124A EP1853906A4 EP 1853906 A4 EP1853906 A4 EP 1853906A4 EP 06705124 A EP06705124 A EP 06705124A EP 06705124 A EP06705124 A EP 06705124A EP 1853906 A4 EP1853906 A4 EP 1853906A4
Authority
EP
European Patent Office
Prior art keywords
apparatus
method
sample deposition
deposition
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06705124A
Other languages
German (de)
French (fr)
Other versions
EP1853906A1 (en
Inventor
Thomas Covey
Peter Kovarik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mds Inc Dbt Mds Sciex Division
MDS Sciex Canada
Applera Corp
Original Assignee
Mds Inc Dbt Mds Sciex Division
MDS Sciex Canada
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US65136205P priority Critical
Priority to CA002496481A priority patent/CA2496481A1/en
Priority to US65120305P priority
Application filed by Mds Inc Dbt Mds Sciex Division, MDS Sciex Canada, Applera Corp filed Critical Mds Inc Dbt Mds Sciex Division
Priority to PCT/CA2006/000168 priority patent/WO2006084354A1/en
Publication of EP1853906A1 publication Critical patent/EP1853906A1/en
Publication of EP1853906A4 publication Critical patent/EP1853906A4/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/84Preparation of the fraction to be distributed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0268Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/02Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/027Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/84Preparation of the fraction to be distributed
    • G01N2030/8411Intermediate storage of effluent, including condensation on surface
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/466Flow patterns using more than one column with separation columns in parallel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or superfluid chromatograph
EP06705124A 2005-02-08 2006-02-08 Method and apparatus for sample deposition Withdrawn EP1853906A4 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US65136205P true 2005-02-08 2005-02-08
CA002496481A CA2496481A1 (en) 2005-02-08 2005-02-09 Method and apparatus for sample deposition
US65120305P true 2005-02-10 2005-02-10
PCT/CA2006/000168 WO2006084354A1 (en) 2005-02-08 2006-02-08 Method and apparatus for sample deposition

Publications (2)

Publication Number Publication Date
EP1853906A1 EP1853906A1 (en) 2007-11-14
EP1853906A4 true EP1853906A4 (en) 2010-03-17

Family

ID=36792869

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06705124A Withdrawn EP1853906A4 (en) 2005-02-08 2006-02-08 Method and apparatus for sample deposition

Country Status (3)

Country Link
EP (1) EP1853906A4 (en)
JP (1) JP2008530521A (en)
WO (1) WO2006084354A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162650A (en) * 1991-01-25 1992-11-10 Finnigan Corporation Method and apparatus for multi-stage particle separation with gas addition for a mass spectrometer
US20020092366A1 (en) * 2001-01-17 2002-07-18 Ansgar Brock Sample deposition method and system
US20030034450A1 (en) * 1997-05-23 2003-02-20 Karger Barry L. On-line and off-line deposition of liquid samples for matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy
WO2003037515A1 (en) * 2001-10-26 2003-05-08 Perseptive Biosystems, Inc. Robotic system having positionally adjustable multiple probes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695555A (en) * 1985-06-12 1987-09-22 Keeffe Andrew F O Liquid chromatographic detector and method
US4980057A (en) * 1989-10-03 1990-12-25 General Electric Company Apparatus for mass spectrometric analysis of liquid chromatographic fractions
US5369035A (en) * 1990-08-09 1994-11-29 Fisons Plc Method and apparatus for analytical sample preparation
JP2002502543A (en) * 1997-05-23 2002-01-22 ノースイースタン ユニバーシティ Matrix-assisted laser withdrawal ionization - time of flight (MALDI-tof) online liquid sample deposition interface for mass spectroscopy
US6074880A (en) * 1998-08-28 2000-06-13 Transgenomic, Inc. Sample analyte containing solution fraction collection system, and method of use
US6633031B1 (en) * 1999-03-02 2003-10-14 Advion Biosciences, Inc. Integrated monolithic microfabricated dispensing nozzle and liquid chromatography-electrospray system and method
US6707035B2 (en) * 2000-08-24 2004-03-16 Newton Scientific, Inc. Sample introduction interface for analytical processing of a sample placed on a substrate
JP3831867B2 (en) * 2001-02-09 2006-10-11 独立行政法人科学技術振興機構 METHOD sample dividing and apparatus therefor
JP3705745B2 (en) * 2001-03-05 2005-10-12 学校法人 東洋大学 Micro chemical analysis system
JP2006523142A (en) * 2003-04-10 2006-10-12 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Fluid species formation and control
JP4447852B2 (en) * 2003-05-29 2010-04-07 株式会社島津製作所 Fraction collecting device for liquid chromatograph
JP4174599B2 (en) * 2003-07-08 2008-11-05 株式会社島津製作所 Fractionation apparatus of the high-speed liquid chromatograph

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162650A (en) * 1991-01-25 1992-11-10 Finnigan Corporation Method and apparatus for multi-stage particle separation with gas addition for a mass spectrometer
US20030034450A1 (en) * 1997-05-23 2003-02-20 Karger Barry L. On-line and off-line deposition of liquid samples for matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy
US20020092366A1 (en) * 2001-01-17 2002-07-18 Ansgar Brock Sample deposition method and system
WO2003037515A1 (en) * 2001-10-26 2003-05-08 Perseptive Biosystems, Inc. Robotic system having positionally adjustable multiple probes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006084354A1 *

Also Published As

Publication number Publication date
JP2008530521A (en) 2008-08-07
EP1853906A1 (en) 2007-11-14
WO2006084354A1 (en) 2006-08-17

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