EP1853699A1 - Pluripotent genetically modified human stem cells carrying reporter gene inserted in chromosome 12 at newly identified locus, envy - Google Patents

Pluripotent genetically modified human stem cells carrying reporter gene inserted in chromosome 12 at newly identified locus, envy

Info

Publication number
EP1853699A1
EP1853699A1 EP06704951A EP06704951A EP1853699A1 EP 1853699 A1 EP1853699 A1 EP 1853699A1 EP 06704951 A EP06704951 A EP 06704951A EP 06704951 A EP06704951 A EP 06704951A EP 1853699 A1 EP1853699 A1 EP 1853699A1
Authority
EP
European Patent Office
Prior art keywords
envy
chromosome
stem cells
genetically modified
pluripotent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06704951A
Other languages
German (de)
French (fr)
Other versions
EP1853699A4 (en
Inventor
Magdaline Costa
Mirella Dottori
Edouard Stanley
Andrew Elefanty
Martin Pera
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Australian Stem Cell Centre Ltd
Original Assignee
Australian Stem Cell Centre Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2005901040A external-priority patent/AU2005901040A0/en
Application filed by Australian Stem Cell Centre Ltd filed Critical Australian Stem Cell Centre Ltd
Publication of EP1853699A1 publication Critical patent/EP1853699A1/en
Publication of EP1853699A4 publication Critical patent/EP1853699A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0271—Chimeric animals, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine

Abstract

The present invention provides a genetically modified cell comprising a polynucleotide sequence integrated into the ENVY locus from chromosome 12. The ENVY locus advantageously provides a conduit for the ubiquitous or cell type specific expression of heterologous genes in human stem cells.
EP06704951A 2005-03-04 2006-03-06 Pluripotent genetically modified human stem cells carrying reporter gene inserted in chromosome 12 at newly identified locus, envy Withdrawn EP1853699A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2005901040A AU2005901040A0 (en) 2005-03-04 Expression vector
PCT/AU2006/000278 WO2006092023A1 (en) 2005-03-04 2006-03-06 Pluripotent genetically modified human stem cells carrying reporter gene inserted in chromosome 12 at newly identified locus, envy

Publications (2)

Publication Number Publication Date
EP1853699A1 true EP1853699A1 (en) 2007-11-14
EP1853699A4 EP1853699A4 (en) 2009-04-22

Family

ID=36940791

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06704951A Withdrawn EP1853699A4 (en) 2005-03-04 2006-03-06 Pluripotent genetically modified human stem cells carrying reporter gene inserted in chromosome 12 at newly identified locus, envy

Country Status (4)

Country Link
EP (1) EP1853699A4 (en)
CA (1) CA2599784A1 (en)
IL (1) IL185685A0 (en)
WO (1) WO2006092023A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2967060A1 (en) 2014-11-10 2016-05-19 Murdoch Childrens Research Institute Vectors and methods for targeted integration in loci comprising constitutively expressed genes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020743A1 (en) * 2001-09-05 2003-03-13 Regeneron Pharmaceuticals, Inc. Methods of expressing transgenes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003020743A1 (en) * 2001-09-05 2003-03-13 Regeneron Pharmaceuticals, Inc. Methods of expressing transgenes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006092023A1 *

Also Published As

Publication number Publication date
CA2599784A1 (en) 2006-09-08
IL185685A0 (en) 2008-01-06
WO2006092023A1 (en) 2006-09-08
EP1853699A4 (en) 2009-04-22

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