EP1848981A4 - Method for determining redox activity and screening compounds based on redox activity - Google Patents

Method for determining redox activity and screening compounds based on redox activity

Info

Publication number
EP1848981A4
EP1848981A4 EP06734783A EP06734783A EP1848981A4 EP 1848981 A4 EP1848981 A4 EP 1848981A4 EP 06734783 A EP06734783 A EP 06734783A EP 06734783 A EP06734783 A EP 06734783A EP 1848981 A4 EP1848981 A4 EP 1848981A4
Authority
EP
European Patent Office
Prior art keywords
redox activity
compounds based
determining
screening compounds
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06734783A
Other languages
German (de)
French (fr)
Other versions
EP1848981A2 (en
Inventor
Jonathan J Abramson
Benjamin S Marinov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oregon State Board of Higher Education
Oregon State
Original Assignee
Oregon State Board of Higher Education
Oregon State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/340,938 external-priority patent/US20060188997A1/en
Application filed by Oregon State Board of Higher Education, Oregon State filed Critical Oregon State Board of Higher Education
Publication of EP1848981A2 publication Critical patent/EP1848981A2/en
Publication of EP1848981A4 publication Critical patent/EP1848981A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G01N31/223—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating presence of specific gases or aerosols
    • G01N31/224—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating presence of specific gases or aerosols for investigating presence of dangerous gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
EP06734783A 2005-02-09 2006-02-09 Method for determining redox activity and screening compounds based on redox activity Withdrawn EP1848981A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65173005P 2005-02-09 2005-02-09
US11/340,938 US20060188997A1 (en) 2005-01-28 2006-01-27 Detection of superoxide ions
PCT/US2006/004803 WO2006086670A2 (en) 2005-02-09 2006-02-09 Method for determining redox activity and screening compounds based on redox activity

Publications (2)

Publication Number Publication Date
EP1848981A2 EP1848981A2 (en) 2007-10-31
EP1848981A4 true EP1848981A4 (en) 2012-01-18

Family

ID=36793779

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06734783A Withdrawn EP1848981A4 (en) 2005-02-09 2006-02-09 Method for determining redox activity and screening compounds based on redox activity

Country Status (2)

Country Link
EP (1) EP1848981A4 (en)
WO (1) WO2006086670A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2418950A4 (en) 2009-04-15 2012-10-24 State Of Oregon By & Through The State Board Of Higher Education On Behalf Of Portland State Unv Compounds and methods for modulating activity of calcium release channels
CN113087703B (en) * 2021-03-03 2022-04-15 四川大学华西医院 Photosensitizer capable of specifically marking lipid droplets and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
CN1644708A (en) * 1998-11-13 2005-07-27 永信药品工业股份有限公司 Mycobacterium tuberculosis superoxide dismutase

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BEAUCHAMP C ET AL: "Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels", ANALYTICAL BIOCHEMISTRY, vol. 44, no. 1, 1 November 1971 (1971-11-01), pages 276 - 287, XP024817484, ISSN: 0003-2697, DOI: 10.1016/0003-2697(71)90370-8 *
BENOV L ET AL: "Is reduction of the sulfonated tetrazolium 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2-tetrazolium 5-carboxanilide a reliable measure for intracellular superoxide production?", ANALYTICAL BIOCHEMISTRY, vol. 310, 2002, XP055014124, ISSN: 0003-2697 *
MARINOV B S ET AL: "Estimation of redox properties of chemical compounds by their reactions with free radicals", ANALYTICAL BIOCHEMISTRY, vol. 220, no. 1, 1 July 1994 (1994-07-01), pages 154 - 159, XP024763248, ISSN: 0003-2697, DOI: 10.1006/ABIO.1994.1312 *
MARINOV B S ET AL: "Redox properties of benzocaine and its homologs", MEMBRANE AND CELL BIOLOGY, vol. 11, no. 4, 1 January 1997 (1997-01-01), pages 507 - 513, XP009154604, ISSN: 1023-6597 *
RAO P S ET AL: "Redox potentials of free radicals. I. Simple organic radicals", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 96, no. 5, 6 March 1974 (1974-03-06), XP055013934, ISSN: 0002-7863, DOI: 10.1021/ja00812a004 *

Also Published As

Publication number Publication date
EP1848981A2 (en) 2007-10-31
WO2006086670A2 (en) 2006-08-17
WO2006086670A3 (en) 2007-01-11

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