EP1843739A1 - Composition de dentifrice - Google Patents

Composition de dentifrice

Info

Publication number
EP1843739A1
EP1843739A1 EP05823840A EP05823840A EP1843739A1 EP 1843739 A1 EP1843739 A1 EP 1843739A1 EP 05823840 A EP05823840 A EP 05823840A EP 05823840 A EP05823840 A EP 05823840A EP 1843739 A1 EP1843739 A1 EP 1843739A1
Authority
EP
European Patent Office
Prior art keywords
phase
toothpaste
toothpaste composition
composition
outer phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP05823840A
Other languages
German (de)
English (en)
Inventor
Rupesh Kumar Agarwal
Donald P. Gregory
Brian Groves
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever PLC
Unilever NV
Original Assignee
Unilever PLC
Unilever NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever PLC, Unilever NV filed Critical Unilever PLC
Publication of EP1843739A1 publication Critical patent/EP1843739A1/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/03—Liquid compositions with two or more distinct layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Definitions

  • the present invention relates to an oral composition
  • an inner phase disposed substantially coaxially within an outer phase .
  • WO 99/01342 discloses apparatus for inserting plural materials into containers .
  • the apparatus comprises a nozzle with a first hollow member and a second hollow member arranged inside the first hollow member .
  • the nozzle is designed for directing the extrusion of multiple toothpaste phases into a toothpaste container with one phase being arranged within another .
  • the present invention provides a toothpaste according to claim 1.
  • the inner phase is disposed co-axially within the outer phase .
  • the longitudinal axis of the ribbon as dispensed from the toothpaste container falls within the inner phase .
  • the general longitudinal axis of the toothpaste as stored within the toothpaste container falls within the inner phase .
  • Such alignment is understood to be judged by the eye and not mathematically.
  • the inner phase may extend towards or up to the exterior surface of the ribbon .
  • Such extension may be radial , spiral or abstract and, where it is radial or spiral it may be regular or irregular . Regular radial extensions are the most preferred to the consumer .
  • the core may, in cross section be of any shape, for example, star-shaped, square shaped, triangular, etc . These shaped cores are a real plus to the younger consumers . However, it is most preferred that the inner phase comprises no extensions and instead provides nothing more than a regular core to the ribbon. This regular shape is less fussy and provide clean lines to the product which reinforces the impression of cleanliness that toothpastes aim to provide .
  • the improved visual impact resides in the way that the outer phase substantially surrounds in the inner phase .
  • the consumer is likely to see only the outer phase because of the way that the outer phase wraps itself around the inner phase .
  • any negative visual impact resident in the inner phase can be negated by using a relatively low level of a further, second composition which substantially surrounds it .
  • a formulator can concentrate on achieving the most efficacious formulation for the inner phase without worrying about any negative visual impact it might have since these can be provided merely by the second, outer phase .
  • the second, outer phase thus provides the visual impact , e . g . a shiny surface , on behalf of the composition as a whole .
  • the inner phase is opaque .
  • the inner phase comprises chalk as abrasive .
  • Chalk provides an improved abrasive system which also polishes the teeth on brushing .
  • Using chalk in the . inner phase also prevents the user from experiencing any negative taste associated with chalk.
  • the chalk may be precipitated calcium carbonate or fine ground natural chalk, preferably it is fine ground natural chalk which is less reactive with other ingredients and so, again, increases the formulation window.
  • the chalk is present at from 5 to 70% by weight of the first , inner phase .
  • the outer phase comprises abrasive silica . More preferably the outer phase comprises an abrasive silica with a low refractive index. It may be used as the sole abrasive silica, or in conjunction with a low level of other abrasive silicas, e . g . those according to EP 236070.
  • the low refractive index silicas used as abrasives in the present invention are preferably silicas with an apparent refractive index (R. I . ) in the range of 1.41 - 1.47 , preferably 1.435 - 1.445 , preferably having a weight mean particle size of between 5 and 15 mm, a BET
  • abrasive silicas with a lower apparent refractive index may also be used .
  • suitable low refractive index abrasive silicas e . g . having an R. I . of between 1.435 and 1.445
  • Tixosil 63 and 73 ex Rhone Poulenc Sident 10 ex Degussa;
  • the amount of these silicas in the composition generally ranges from 5-60% by weight , usually 5-20% by weight .
  • the outer phase is visually clear.
  • visually-clear is meant that the inner, first phase can be seen through the outer, second phase .
  • the first phase is disposed co-axially within the visually clear gel phase .
  • the longitudinal axis of the ribbon as dispensed from the toothpaste container falls within the inner, first phase .
  • the general longitudinal axis of the toothpaste as stored within the toothpaste container falls within the inner, first phase as stored therein .
  • Such alignment is understood to be judged by the eye and not mathematically.
  • the inner first phase constitutes from 80 to 99% and more preferably from 90 to 95% by volume of the toothpaste composition.
  • the first and second phases may be the same or different with regard to their principle components , i . e . thickeners , actives, structurants and abrasives . Where the first and second phases are essentially the same they may differ in minor components such as colours or flavours . Having two visually clear phases also provides an attractive composition for the consumer .
  • the inner phase comprising the bulk of the efficacious materials with the outer phase providing the attractive appearance on behalf of the formulation as a whole .
  • the inner phase may comprise clays as structurants . Clays do not provide a visually attractive paste and so this inner phase will be surrounded by a second phase which is made up of materials which provide such a visually attractive appearance .
  • At least one of the phases is coloured .
  • the outer, visually-clear phase is coloured .
  • Preferred colours include green, red, orange, yellow, blue , gold and purple . This would give the impression that the whole composition is coloured where in fact it might not be, the inner phase being merely opaque and colourless .
  • the phases of the composition according to the invention are manufactured using standard processes . They may be extruded into a container for dispensing by equipment such as that discussed in detail in WO 99/01342 , i . e . a coaxial nozzle assembly attached to standard equipment .
  • the phases according to the composition of the invention have viscosities as measured on a Brookfield RV DV-I viscometer fitted with a Helipath stand at 25 °C and 5rpm using a spindle are from 150 000 Pa . s and
  • the toothpaste composition according to the present invention can comprise an agent selected from the group consisting of anti-carries agents , tooth whitening agents, anti-tartar agents , anti-malodour agents , anti-gingivitis agents and mixtures thereof .
  • the toothpaste composition will comprise further ingredients which are common in the art , such as :
  • antimicrobial agents e .g . chlorhexidine, sanguinarine extract , metronidazole, quaternary ammonium compounds , such as cetylpyridinium chloride; bis-guanides , such as chlorhexidine digluconate, hexetidine, octenidine, alexidine ; and halogenated bisphenolic compounds , such as 2 , 2 ' methylenebis- (4-chloro-6-bromophenol) ;
  • anti-inflammatory agents such as ibuprofen, flurbiprofen, aspirin, indomethacin etc . ;
  • anti-caries agents such as sodium- and stannous fluoride , aminefluorides , sodium monofluorophosphate, sodium trimeta phosphate and casein;
  • plaque buffers such as urea, calcium lactate, calcium glycerophosphate and strontium polyacrylates ; vitamins such as Vitamins A, C and E;
  • desensitising agents e .g . potassium citrate, potassium chloride, potassium tartrate , potassium bicarbonate, potassium oxalate , potassium nitrate and strontium salts ;
  • anti-calculus agents e .g . alkali-metal pyrophosphates , hypophosphite-containing polymers , organic phosphonates and phosphocitrates etc . ;
  • biomolecules e . g . bacteriocins , antibodies , enzymes, etc . ;
  • flavours e . g . peppermint and spearmint oils ;
  • proteinaceous materials such as collagen
  • pharmaceutically acceptable carriers e . g . starch, sucrose, water or water/alcohol systems etc .
  • surfactants such as anionic, nonionic, cationic and zwitterionic or amphoteric surfactants ;
  • particulate abrasive materials such as silicas , aluminas , calcium carbonates , dicalciumphosphates , calcium pyrophosphates , hydroxyapatites , trimetaphosphates , insoluble hexametaphosphates and so on, including agglomerated particulate abrasive materials, usually in amounts between 3 and 60% by weight of the oral care composition .
  • Preferred abrasives are chalk and silica, more preferably fine ground natural chalk.
  • Humectants such as glycerol , sorbitol , propyleneglycol , xylitol , lactitol etc . ;
  • binders and thickeners such as sodium carboxymethyl- cellulose, hydroxyethyl cellulose (Natros ⁇ l ® ) , xanthan gum, gum arabic etc . as well as synthetic polymers such as polyacrylates and carboxyvinyl polymers such as Carbopol ® ;
  • polymeric compounds which can enhance the delivery of active ingredients such as antimicrobial agents can also be included;
  • bleaching agents such as peroxy compounds e . g . potassium peroxydiphosphate , effervescing systems such as sodium - S -
  • Liposomes may also be used to improve delivery or stability of active ingredients .
  • the present invention provides a toothpaste container comprising a first and second phase as described in the first aspect of the invention stored within a tubular container, the container comprising a tubular body which is crimped at one end and comprises a dispensing assembly at the other through which the composition is extruded by the consumer.
  • the tubular container is transparent or translucent so that the inner phase can be seen within the outer phase within the container .
  • the first phase makes up 85% by volume of the toothpaste composition .

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

L’invention concerne une composition de dentifrice comprenant une phase intérieure disposée de manière sensiblement coaxiale au sein d’une phase extérieure, la phase intérieure constituant de 60 à 99,9 % en volume de la composition, la phase extérieure étant un gel et constituant de 0,1 à 40 % en volume de la composition.
EP05823840A 2005-02-04 2005-12-21 Composition de dentifrice Ceased EP1843739A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN118MU2005 2005-02-04
IN289KO2005 2005-04-08
PCT/EP2005/014058 WO2006081867A1 (fr) 2005-02-04 2005-12-21 Composition de dentifrice

Publications (1)

Publication Number Publication Date
EP1843739A1 true EP1843739A1 (fr) 2007-10-17

Family

ID=36072147

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05823840A Ceased EP1843739A1 (fr) 2005-02-04 2005-12-21 Composition de dentifrice

Country Status (4)

Country Link
EP (1) EP1843739A1 (fr)
BR (1) BRPI0519870A2 (fr)
MX (1) MX2007009239A (fr)
WO (1) WO2006081867A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201607518D0 (en) * 2016-04-29 2016-06-15 Andalay Technologies Ltd Mouthwash composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1271944A (en) * 1968-07-23 1972-04-26 Beecham Group Ltd Gel toothpastes
US3935305A (en) * 1972-10-04 1976-01-27 Colgate-Palmolive Company Toothpaste
WO2002015856A1 (fr) * 2000-08-21 2002-02-28 Unilever N.V. Pate dentaire aqueuse comprenant un support et un principe actif melanges par cobroyage

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2006081867A1 *

Also Published As

Publication number Publication date
MX2007009239A (es) 2007-09-19
BRPI0519870A2 (pt) 2009-03-24
WO2006081867A1 (fr) 2006-08-10

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Legal Events

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Effective date: 20070625

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Effective date: 20080424

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: UNILEVER N.V.

Owner name: UNILEVER PLC

STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 20100529