EP1812066A4 - VACCINES, COMPOSITIONS AND METHODS BASED ON STAPHYLOCOCCUS AUREUS IRON-REGULATED SURFACE DETERMINANTS IsdA, IsdB, and IsdC - Google Patents

VACCINES, COMPOSITIONS AND METHODS BASED ON STAPHYLOCOCCUS AUREUS IRON-REGULATED SURFACE DETERMINANTS IsdA, IsdB, and IsdC

Info

Publication number
EP1812066A4
EP1812066A4 EP05850805A EP05850805A EP1812066A4 EP 1812066 A4 EP1812066 A4 EP 1812066A4 EP 05850805 A EP05850805 A EP 05850805A EP 05850805 A EP05850805 A EP 05850805A EP 1812066 A4 EP1812066 A4 EP 1812066A4
Authority
EP
European Patent Office
Prior art keywords
isdc
isda
isdb
vaccines
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05850805A
Other languages
German (de)
French (fr)
Other versions
EP1812066A2 (en
Inventor
David E Heinrichs
Christie Vermeiren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Western Ontario
Original Assignee
University of Western Ontario
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Western Ontario filed Critical University of Western Ontario
Publication of EP1812066A2 publication Critical patent/EP1812066A2/en
Publication of EP1812066A4 publication Critical patent/EP1812066A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
EP05850805A 2004-10-25 2005-10-25 VACCINES, COMPOSITIONS AND METHODS BASED ON STAPHYLOCOCCUS AUREUS IRON-REGULATED SURFACE DETERMINANTS IsdA, IsdB, and IsdC Withdrawn EP1812066A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62192104P 2004-10-25 2004-10-25
PCT/IB2005/004126 WO2006059247A2 (en) 2004-10-25 2005-10-25 VACCINES, COMPOSITIONS AND METHODS BASED ON STAPHYLOCOCCUS AUREUS IRON-REGULATED SURFACE DETERMINANTS IsdA, IsdB, and IsdC

Publications (2)

Publication Number Publication Date
EP1812066A2 EP1812066A2 (en) 2007-08-01
EP1812066A4 true EP1812066A4 (en) 2010-06-30

Family

ID=36565416

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05850805A Withdrawn EP1812066A4 (en) 2004-10-25 2005-10-25 VACCINES, COMPOSITIONS AND METHODS BASED ON STAPHYLOCOCCUS AUREUS IRON-REGULATED SURFACE DETERMINANTS IsdA, IsdB, and IsdC

Country Status (6)

Country Link
EP (1) EP1812066A4 (en)
JP (1) JP2008517900A (en)
KR (1) KR20070085457A (en)
AU (1) AU2005310981A1 (en)
CA (1) CA2581746A1 (en)
WO (1) WO2006059247A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007009828A (en) 2005-02-14 2007-09-27 Epitopix Llc Polypeptides from staphylococcus aureus and methods of use.
US20090317421A1 (en) * 2006-01-18 2009-12-24 Dominique Missiakas Compositions and methods related to staphylococcal bacterium proteins
EP3141261A1 (en) 2006-03-30 2017-03-15 GlaxoSmithKline Biologicals S.A. Immunogenic composition
WO2008152447A2 (en) * 2006-10-30 2008-12-18 The University Of Western Ontario Staphylococcus aureus specific anti-infectives
EP2185190B1 (en) 2007-08-31 2015-06-24 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
US8758765B2 (en) 2008-07-29 2014-06-24 The University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
KR101770321B1 (en) * 2009-03-23 2017-09-05 이피토픽스, 엘엘씨 Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use
PL2414387T3 (en) 2009-04-03 2016-06-30 Univ Chicago Compositions and methods related to protein a (spa) variants
GB0913681D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
GB0913680D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
KR20130093084A (en) 2010-07-02 2013-08-21 더 유니버시티 오브 시카고 Compositions and methods related to protein a(spa) variants
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
WO2014144423A2 (en) * 2013-03-15 2014-09-18 Techulon Inc. Antisense molecules for treatment of staphylococcus aureus infection
US9834768B2 (en) 2014-12-31 2017-12-05 Korea Advanced Institute Of Science And Technology Effective method for specific gene silencing using artificial small RNA

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102829A2 (en) * 2001-06-15 2002-12-27 Inhibitex, Inc. Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus
WO2003011899A2 (en) * 2001-08-02 2003-02-13 University Of Sheffield Antigenic polypeptides
WO2005009379A2 (en) * 2003-07-24 2005-02-03 Merck & Co., Inc. Polypeptides for inducing a protective immune response against staphylococcus aureus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077183A2 (en) * 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
JP2008513409A (en) * 2004-09-22 2008-05-01 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Immunogenic composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102829A2 (en) * 2001-06-15 2002-12-27 Inhibitex, Inc. Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus
WO2003011899A2 (en) * 2001-08-02 2003-02-13 University Of Sheffield Antigenic polypeptides
WO2005009379A2 (en) * 2003-07-24 2005-02-03 Merck & Co., Inc. Polypeptides for inducing a protective immune response against staphylococcus aureus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLARKE S R ET AL: "IDENTIFICATION OF IN VIVO-EXPRESSED ANTIGENS OF STAPHYLOCOCCUS AUREUS AND THEIR USE IN VACCINATIONS FOR PROTECTION AGAINST NASAL CARRIAGE", JOURNAL OF INFECTIOUS DISEASES, UNIVERSITY OF CHICAGO PRESS, CHICAGO, IL LNKD- DOI:10.1086/501471, vol. 193, no. 8, 1 January 2006 (2006-01-01), pages 1098 - 1108, XP009064347, ISSN: 0022-1899 *
KUKLIN NELLY A ET AL: "A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus macaques and specific increased survival in a murine S. aureus sepsis model", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US LNKD- DOI:10.1128/IAI.74.4.2215-2223.2006, vol. 74, no. 4, 1 April 2006 (2006-04-01), pages 2215 - 2223, XP002517728, ISSN: 0019-9567 *
STRANGER-JONES YUKIKO K ET AL: "Vaccine assembly from surface proteins of Staphylococcus aureus", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 7 NOV 2006,, vol. 103, no. 45, 7 November 2006 (2006-11-07), pages 16942 - 16947, XP002517729 *

Also Published As

Publication number Publication date
WO2006059247A3 (en) 2006-10-05
EP1812066A2 (en) 2007-08-01
AU2005310981A1 (en) 2006-06-08
WO2006059247A8 (en) 2007-04-26
WO2006059247A2 (en) 2006-06-08
KR20070085457A (en) 2007-08-27
CA2581746A1 (en) 2006-06-08
JP2008517900A (en) 2008-05-29

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