EP1809255A4 - Hochdosierte formulierung von gepiron mit verlängerter freisetzung - Google Patents
Hochdosierte formulierung von gepiron mit verlängerter freisetzungInfo
- Publication number
- EP1809255A4 EP1809255A4 EP04800476A EP04800476A EP1809255A4 EP 1809255 A4 EP1809255 A4 EP 1809255A4 EP 04800476 A EP04800476 A EP 04800476A EP 04800476 A EP04800476 A EP 04800476A EP 1809255 A4 EP1809255 A4 EP 1809255A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- gepirone
- release formulation
- dosage extended
- dosage
- extended
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000013265 extended release Methods 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- QOIGKGMMAGJZNZ-UHFFFAOYSA-N gepirone Chemical compound O=C1CC(C)(C)CC(=O)N1CCCCN1CCN(C=2N=CC=CN=2)CC1 QOIGKGMMAGJZNZ-UHFFFAOYSA-N 0.000 title 1
- 229960000647 gepirone Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2004/032785 WO2006052227A1 (en) | 2004-11-05 | 2004-11-05 | High-dosage extended-release formulation of gepirone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1809255A1 EP1809255A1 (de) | 2007-07-25 |
| EP1809255A4 true EP1809255A4 (de) | 2011-08-03 |
Family
ID=36336794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP04800476A Withdrawn EP1809255A4 (de) | 2004-11-05 | 2004-11-05 | Hochdosierte formulierung von gepiron mit verlängerter freisetzung |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1809255A4 (de) |
| JP (1) | JP2008519071A (de) |
| CN (1) | CN101076320A (de) |
| AU (1) | AU2004324868B2 (de) |
| BR (1) | BRPI0419179A (de) |
| CA (1) | CA2585606A1 (de) |
| EA (1) | EA013213B1 (de) |
| IL (1) | IL182792A0 (de) |
| MX (1) | MX2007005368A (de) |
| NO (1) | NO20072851L (de) |
| WO (1) | WO2006052227A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20131906A1 (it) * | 2013-11-18 | 2015-05-19 | Gnosis Spa | Composizioni solide orali a lento rilascio |
| RU2713725C1 (ru) * | 2019-02-08 | 2020-02-06 | Юрий Владимирович Соколов | Биологически активная добавка и способ ее применения |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002045753A2 (en) * | 2000-12-08 | 2002-06-13 | Akzo Nobel N.V. | Oral extended release formulation of gepirone |
| US20030220346A1 (en) * | 2000-12-18 | 2003-11-27 | Kramer Stephen J. | Use of bioactive metabolites of gepirone for the treatment of psychological disorders |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423049A (en) * | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
| US5478572A (en) * | 1994-09-06 | 1995-12-26 | Bristol-Myers Squibb Co. | Gepirone dosage form |
| US6534507B1 (en) * | 1999-12-20 | 2003-03-18 | Fabre-Kramer Pharmaceuticals, Inc. | Methods for treating psychological disorders using bioactive metabolites of gepirone |
-
2004
- 2004-11-05 EP EP04800476A patent/EP1809255A4/de not_active Withdrawn
- 2004-11-05 CA CA002585606A patent/CA2585606A1/en not_active Abandoned
- 2004-11-05 EA EA200701010A patent/EA013213B1/ru not_active IP Right Cessation
- 2004-11-05 JP JP2007540289A patent/JP2008519071A/ja active Pending
- 2004-11-05 CN CNA2004800445809A patent/CN101076320A/zh active Pending
- 2004-11-05 WO PCT/US2004/032785 patent/WO2006052227A1/en not_active Ceased
- 2004-11-05 AU AU2004324868A patent/AU2004324868B2/en not_active Expired - Fee Related
- 2004-11-05 BR BRPI0419179-0A patent/BRPI0419179A/pt not_active Application Discontinuation
- 2004-11-05 MX MX2007005368A patent/MX2007005368A/es not_active Application Discontinuation
-
2007
- 2007-04-26 IL IL182792A patent/IL182792A0/en unknown
- 2007-06-05 NO NO20072851A patent/NO20072851L/no not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002045753A2 (en) * | 2000-12-08 | 2002-06-13 | Akzo Nobel N.V. | Oral extended release formulation of gepirone |
| US20030220346A1 (en) * | 2000-12-18 | 2003-11-27 | Kramer Stephen J. | Use of bioactive metabolites of gepirone for the treatment of psychological disorders |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO2006052227A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2585606A1 (en) | 2006-05-18 |
| CN101076320A (zh) | 2007-11-21 |
| AU2004324868B2 (en) | 2010-04-29 |
| EA200701010A1 (ru) | 2007-10-26 |
| EA013213B1 (ru) | 2010-04-30 |
| AU2004324868A1 (en) | 2006-05-18 |
| JP2008519071A (ja) | 2008-06-05 |
| IL182792A0 (en) | 2007-08-19 |
| BRPI0419179A (pt) | 2007-12-18 |
| EP1809255A1 (de) | 2007-07-25 |
| MX2007005368A (es) | 2007-09-11 |
| WO2006052227A1 (en) | 2006-05-18 |
| NO20072851L (no) | 2007-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20070426 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LU MC NL PL PT RO SE SI SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL HR LT LV MK YU |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: FABRE-KRAMER HOLDINGS, INC. |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1107676 Country of ref document: HK |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20110704 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/506 20060101ALI20110628BHEP Ipc: A61K 9/48 20060101ALI20110628BHEP Ipc: A61K 9/20 20060101AFI20110628BHEP |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20111001 |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1107676 Country of ref document: HK |