EP1807123A4 - Verfahren zur verbesserung der toleranz gebenüber therapeutisch wirksamen mitteln, die durch inhalation abgegeben werden - Google Patents

Verfahren zur verbesserung der toleranz gebenüber therapeutisch wirksamen mitteln, die durch inhalation abgegeben werden

Info

Publication number
EP1807123A4
EP1807123A4 EP05790821A EP05790821A EP1807123A4 EP 1807123 A4 EP1807123 A4 EP 1807123A4 EP 05790821 A EP05790821 A EP 05790821A EP 05790821 A EP05790821 A EP 05790821A EP 1807123 A4 EP1807123 A4 EP 1807123A4
Authority
EP
European Patent Office
Prior art keywords
inhalation
tolerance
improvement
therapeutically effective
effective agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05790821A
Other languages
English (en)
French (fr)
Other versions
EP1807123A2 (de
Inventor
William R Baker
Thomas Hofmann
Alan Bruce Montgomery
Kevin Stapleton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Sciences Inc
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2004/036926 external-priority patent/WO2005044233A1/en
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of EP1807123A2 publication Critical patent/EP1807123A2/de
Publication of EP1807123A4 publication Critical patent/EP1807123A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP05790821A 2004-09-20 2005-01-28 Verfahren zur verbesserung der toleranz gebenüber therapeutisch wirksamen mitteln, die durch inhalation abgegeben werden Withdrawn EP1807123A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61165604P 2004-09-20 2004-09-20
PCT/US2004/036926 WO2005044233A1 (en) 2003-11-04 2004-11-04 Formulations of n-oxide prodrugs of local anesthetics for the treatment of pulmonary inflammation associated with asthma, brochitis, and copd
US63502204P 2004-12-09 2004-12-09
PCT/US2005/003532 WO2006060027A2 (en) 2004-09-20 2005-01-28 A method for improvement of tolerance for therapeutically effective agents delivered by inhalation

Publications (2)

Publication Number Publication Date
EP1807123A2 EP1807123A2 (de) 2007-07-18
EP1807123A4 true EP1807123A4 (de) 2010-01-13

Family

ID=36565461

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05790821A Withdrawn EP1807123A4 (de) 2004-09-20 2005-01-28 Verfahren zur verbesserung der toleranz gebenüber therapeutisch wirksamen mitteln, die durch inhalation abgegeben werden

Country Status (4)

Country Link
EP (1) EP1807123A4 (de)
AU (1) AU2005310312A1 (de)
CA (1) CA2581053A1 (de)
WO (1) WO2006060027A2 (de)

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US10617703B2 (en) 2014-12-10 2020-04-14 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11278590B2 (en) 2015-08-05 2022-03-22 Cmpd Licensing, Llc Compositions and methods for treating nail infections
US10898455B2 (en) 2016-01-07 2021-01-26 Cmpd Licensing, Llc Urea cream formulations
US11793783B2 (en) 2015-08-05 2023-10-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11684567B2 (en) 2015-08-05 2023-06-27 Cmpd Licensing, Llc Compositions and methods for treating an infection
US10898491B2 (en) 2015-12-18 2021-01-26 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11690815B2 (en) 2015-08-05 2023-07-04 Cmpd Licensing Llc Hyperkeratotic skin condition treatments and compositions
JP2018535984A (ja) * 2015-11-18 2018-12-06 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ リバビリンの医薬組成物
CN105920020B (zh) * 2016-06-23 2019-01-08 潘海英 一种治疗肺部疾病的药物组合物及其制备方法和用途
US11986448B2 (en) 2016-11-17 2024-05-21 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
US11737975B2 (en) 2016-11-17 2023-08-29 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
US10966946B2 (en) 2016-11-17 2021-04-06 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
US9999604B2 (en) 2016-11-17 2018-06-19 Cmpd Licensing, Llc Compounded solutions of diclofenac and lidocaine and methods
US10525025B2 (en) 2016-11-17 2020-01-07 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
EP3618824A4 (de) 2017-05-02 2021-06-23 Neuronasal, LLC Verwendung von n-acetylcystein zur behandlung von erkrankungen des zentralen nervensystems

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037896A1 (en) * 1997-02-26 1998-09-03 Mayo Foundation For Medical Education And Research Treatment of eosinophil-associated pathologies, such as bronchial asthma, with synergistic combinations of glucocorticoids and a local anesthetics
US20030171402A1 (en) * 2000-06-23 2003-09-11 Gleich Gerald J. Method of treating neutrophil-related diseases with topical anesthetics

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037896A1 (en) * 1997-02-26 1998-09-03 Mayo Foundation For Medical Education And Research Treatment of eosinophil-associated pathologies, such as bronchial asthma, with synergistic combinations of glucocorticoids and a local anesthetics
US20030171402A1 (en) * 2000-06-23 2003-09-11 Gleich Gerald J. Method of treating neutrophil-related diseases with topical anesthetics

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DECCO M L ET AL: "Nebulized lidocaine in the treatment of severe asthma in children: a pilot study", ANNALS OF ALLERGY, ASTHMA & IMMUNOLOGY, ARLINGTON HEIGHTS, IL, US, vol. 82, no. 1, 1 January 1999 (1999-01-01), pages 29 - 32, XP009126326, ISSN: 1081-1206 *
HUNT L W ET AL: "EFFECT OF NEBULIZED LIDOCAINE ON SEVERE GLUCOCORTICOID-DEPENDENT ASTHMA", MAYO CLINIC PROCEEDINGS, MAYO MEDICAL VENTURES, ROCHESTER, MN, vol. 71, no. 4, 1 April 1996 (1996-04-01), pages 361 - 368, XP002069072, ISSN: 0025-6196 *
IACONO A T ET AL: "DOSE-RELATED REVERSAL OF ACTUE LUNG REJECTION BY AEROSOLIZED CYCLOSPORINE", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMERICAN LUNG ASSOCIATION, NEW YORK, NY, US, vol. 155, no. 5, 1 May 1997 (1997-05-01), pages 1690 - 1698, XP000939164, ISSN: 1073-449X *
PARI AEROSOL RESEARCH INSTITUTE: "PARI's eFlow(R), an Electronic Aerosol Device for Medication Delivery, Receives FDA 510(k) Market Clearance", 18 May 2004 (2004-05-18), Monterey, California, USA, pages 1 - 2, XP002558312, Retrieved from the Internet <URL:http://www2.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/05-18-2004/0002176356&EDATE> [retrieved on 20091201] *

Also Published As

Publication number Publication date
EP1807123A2 (de) 2007-07-18
AU2005310312A1 (en) 2006-06-08
WO2006060027A3 (en) 2007-12-13
CA2581053A1 (en) 2006-06-08
WO2006060027A2 (en) 2006-06-08

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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AX Request for extension of the european patent

Extension state: AL BA HR LV MK YU

RIN1 Information on inventor provided before grant (corrected)

Inventor name: STAPLETON, KEVIN

Inventor name: MONTGOMERY, ALAN, BRUCE

Inventor name: HOFMANN, THOMAS

Inventor name: BAKER, WILLIAM, R.

DAX Request for extension of the european patent (deleted)
R17D Deferred search report published (corrected)

Effective date: 20071213

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GILEAD SCIENCES, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20091216

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/47 20060101ALI20091208BHEP

Ipc: A61K 31/24 20060101ALI20091208BHEP

Ipc: A61K 9/14 20060101ALI20091208BHEP

Ipc: A61K 9/12 20060101AFI20091208BHEP

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Effective date: 20120801