EP1773388A4 - Sars vaccines and methods to produce highly potent antibodies - Google Patents

Sars vaccines and methods to produce highly potent antibodies

Info

Publication number
EP1773388A4
EP1773388A4 EP05786720A EP05786720A EP1773388A4 EP 1773388 A4 EP1773388 A4 EP 1773388A4 EP 05786720 A EP05786720 A EP 05786720A EP 05786720 A EP05786720 A EP 05786720A EP 1773388 A4 EP1773388 A4 EP 1773388A4
Authority
EP
European Patent Office
Prior art keywords
methods
highly potent
produce highly
potent antibodies
sars vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05786720A
Other languages
German (de)
French (fr)
Other versions
EP1773388A2 (en
Inventor
Shibo Jiang
Yuxian He
Shuwen Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Blood Center Inc
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Publication of EP1773388A2 publication Critical patent/EP1773388A2/en
Publication of EP1773388A4 publication Critical patent/EP1773388A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP05786720A 2004-06-02 2005-06-01 Sars vaccines and methods to produce highly potent antibodies Withdrawn EP1773388A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57611804P 2004-06-02 2004-06-02
US14192505A 2005-05-31 2005-05-31
PCT/US2005/019266 WO2005120565A2 (en) 2004-06-02 2005-06-01 Sars vaccines and methods to produce highly potent antibodies

Publications (2)

Publication Number Publication Date
EP1773388A2 EP1773388A2 (en) 2007-04-18
EP1773388A4 true EP1773388A4 (en) 2008-08-20

Family

ID=35503665

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05786720A Withdrawn EP1773388A4 (en) 2004-06-02 2005-06-01 Sars vaccines and methods to produce highly potent antibodies

Country Status (4)

Country Link
EP (1) EP1773388A4 (en)
AU (1) AU2005251738A1 (en)
CA (1) CA2569142A1 (en)
WO (1) WO2005120565A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115190911B (en) * 2020-02-10 2024-04-23 港大科桥有限公司 Composition having immunogenicity against SARS coronavirus 2, its preparation method and use
KR20220144829A (en) * 2020-02-19 2022-10-27 유나이티드 바이오메디칼 인크. Peptides and proteins designed for detection, prevention and treatment of coronavirus disease, 2019 (COVID-19)
CN113321715B (en) * 2020-02-28 2023-02-17 北京万泰生物药业股份有限公司 Novel coronavirus antigen and detection use thereof
US11857620B2 (en) 2020-03-11 2024-01-02 Immunitybio, Inc. Method of inducing immunity against SARS-CoV-2 using spike (s) and nucleocapsid (N)-ETSD immunogens delivered by a replication-defective adenovirus
US20210284716A1 (en) 2020-03-11 2021-09-16 Immunitybio, Inc. ACE2-Fc Trap
WO2021195089A1 (en) * 2020-03-23 2021-09-30 Sorrento Therapeutics, Inc. Fc-coronavirus antigen fusion proteins, and nucleic acids, vectors, compositions and methods of use thereof
CN111983226A (en) 2020-03-25 2020-11-24 新加坡国立大学 Detection of SARSr-CoV antibodies
CN113461828B (en) * 2020-03-30 2023-10-27 北京科兴中维生物技术有限公司 Recombinant protein vaccine for 2019-nCoV and preparation method thereof
CN111574622A (en) * 2020-04-07 2020-08-25 刘会芳 Antibody for resisting novel human coronavirus pneumonia and preparation method thereof
CN113527444B (en) * 2020-04-13 2022-12-27 中国科学院微生物研究所 Epitopes effective binding to antibodies of novel coronaviruses
EP4150071A1 (en) * 2020-05-11 2023-03-22 Lysando AG Virus neutralization by soluble receptor fragments of the ace-2 receptor
CN111574623A (en) * 2020-05-25 2020-08-25 西安咸辅生物科技有限责任公司 Preparation method of novel coronavirus S1+ S2 anti-idiotype yolk antibody vaccine
WO2021237516A1 (en) * 2020-05-27 2021-12-02 上海济煜医药科技有限公司 Sars-cov-2 antibody and application thereof
WO2021239147A1 (en) * 2020-05-29 2021-12-02 中国科学院微生物研究所 β-CORONAVIRUS ANTIGEN, β-CORONAVIRUS BIVALENT VACCINE, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF
EP3925971A1 (en) * 2020-06-16 2021-12-22 Viravaxx AG Method for identifying compounds influencing virus receptor binding
CN113797326B (en) * 2020-06-17 2024-01-19 上海君实生物医药科技股份有限公司 Vaccine for preventing diseases caused by coronaviruses
CN115777064A (en) * 2020-07-19 2023-03-10 南特细胞公司 COVID-19 mucosal antibody assay
CN111808199A (en) * 2020-07-27 2020-10-23 西安咸辅生物科技有限责任公司 Preparation method of ACE2 anti-idiotype yolk antibody vaccine
CN114057845A (en) * 2020-08-07 2022-02-18 清华大学 Polypeptide for preventing novel coronavirus pneumonia COVID-19, immunogenic conjugate and application thereof
CN112225814A (en) * 2020-09-29 2021-01-15 东莞博盛生物科技有限公司 Novel coronavirus RBD fusion protein subunit vaccine and preparation method and application thereof
CN112480268B (en) * 2020-12-10 2021-08-03 北京康乐卫士生物技术股份有限公司 Novel recombinant subunit vaccine of coronavirus and application thereof
CN116333161B (en) * 2021-02-04 2024-01-26 广东克冠达医药科技有限公司 COVID-19 subunit vaccine and preparation method and application thereof
GB2606693A (en) * 2021-04-08 2022-11-23 Exosis Inc Fusion protein
CN113583137B (en) * 2021-06-15 2022-08-05 北京康乐卫士生物技术股份有限公司 Novel recombinant subunit vaccine of coronavirus south Africa mutant strain and application thereof
CN116375881A (en) * 2021-12-31 2023-07-04 广州国家实验室 Fusion protein vaccine

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BISHT HIMANI ET AL: "Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 101, no. 17, 27 April 2004 (2004-04-27), pages 6641 - 6646, XP002391528, ISSN: 0027-8424 *
BONAVIA A ET AL: "Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 77, no. 4, February 2003 (2003-02-01), pages 2530 - 2538, XP002342003, ISSN: 0022-538X *
HE Y ET AL: "Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 324, no. 2, 12 November 2004 (2004-11-12), pages 773 - 781, XP004599673, ISSN: 0006-291X *
LI WENHUI ET AL: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 426, no. 6965, 27 November 2003 (2003-11-27), pages 450 - 454, XP002342002, ISSN: 0028-0836 *
SUI JIANHUA ET AL: "Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 101, no. 8, 24 February 2004 (2004-02-24), pages 2536 - 2541, XP002332534, ISSN: 0027-8424 *
WONG SWEE KEE ET AL: "A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 279, no. 5, 30 January 2004 (2004-01-30), pages 3197 - 3201, XP002332535, ISSN: 0021-9258 *
YANG ZHI-YONG ET AL: "A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 428, no. 6982, 1 April 2004 (2004-04-01), pages 561 - 564, XP002304794, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
CA2569142A1 (en) 2005-12-22
WO2005120565A8 (en) 2006-02-09
AU2005251738A1 (en) 2005-12-22
WO2005120565A2 (en) 2005-12-22
WO2005120565A3 (en) 2007-05-18
EP1773388A2 (en) 2007-04-18

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20070101

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR LV MK YU

RIN1 Information on inventor provided before grant (corrected)

Inventor name: LIU, SHUWEN

Inventor name: HE, YUXIAN

Inventor name: JIANG, SHIBO

R17D Deferred search report published (corrected)

Effective date: 20070518

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 1/00 20060101ALI20070724BHEP

Ipc: A61K 39/215 20060101AFI20070724BHEP

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20080717

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