EP1732599A4 - Use of emmprin antagonists for the treatment of diseases associated with excessive angiogenesis - Google Patents
Use of emmprin antagonists for the treatment of diseases associated with excessive angiogenesisInfo
- Publication number
- EP1732599A4 EP1732599A4 EP04821758A EP04821758A EP1732599A4 EP 1732599 A4 EP1732599 A4 EP 1732599A4 EP 04821758 A EP04821758 A EP 04821758A EP 04821758 A EP04821758 A EP 04821758A EP 1732599 A4 EP1732599 A4 EP 1732599A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- treatment
- diseases associated
- excessive angiogenesis
- emmprin antagonists
- emmprin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2004/009151 WO2005092381A1 (en) | 2004-03-25 | 2004-03-25 | Use of emmprin antagonists for the treatment of diseases associated with excessive angiogenesis |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1732599A1 EP1732599A1 (en) | 2006-12-20 |
EP1732599A4 true EP1732599A4 (en) | 2008-05-14 |
Family
ID=35055994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04821758A Withdrawn EP1732599A4 (en) | 2004-03-25 | 2004-03-25 | Use of emmprin antagonists for the treatment of diseases associated with excessive angiogenesis |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1732599A4 (en) |
JP (1) | JP2007530538A (en) |
CN (1) | CN1960753A (en) |
AU (1) | AU2004317548A1 (en) |
CA (1) | CA2560903A1 (en) |
WO (1) | WO2005092381A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4911950B2 (en) * | 2005-11-07 | 2012-04-04 | 晃 伊東 | Cancer invasion / metastasis inhibitor using partial peptide of MMP-1 |
AU2009296937B2 (en) * | 2008-09-29 | 2015-02-12 | Centocor Ortho Biotech Inc. | Anti-CD147 antibodies, methods, and uses |
US10709702B2 (en) * | 2015-10-08 | 2020-07-14 | Amd Therapeutics Llc | Treatment of skin disorders by topical administration of VEGF inhibitors |
CN108101993B (en) * | 2018-01-02 | 2019-10-15 | 北京大学 | A kind of anti-CD147 nano antibody, its production method and application |
EP3749373A1 (en) | 2018-02-07 | 2020-12-16 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for therapeutic protein delivery |
WO2021215836A1 (en) * | 2020-04-22 | 2021-10-28 | 신풍제약주식회사 | Pharmaceutical composition for treating or preventing eye diseases comprising verbenone derivative |
CN114525252B (en) * | 2022-03-10 | 2023-12-01 | 广州源井生物科技有限公司 | Monoclonal enhancement culture medium for improving MDA-MB-231 monoclonal formation rate, culture method and application thereof |
WO2023174147A1 (en) * | 2022-03-18 | 2023-09-21 | Alphelix Biotech Co., Ltd. | Antibodies specifically binding to cd147 and uses thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999045031A2 (en) * | 1998-03-03 | 1999-09-10 | Abgenix, Inc. | Cd147 binding molecules as therapeutics |
WO2002013763A2 (en) * | 2000-08-10 | 2002-02-21 | The Picower Institute For Medical Research | Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists |
WO2002094875A1 (en) * | 2001-05-25 | 2002-11-28 | Zhinan Chen | HAb18G/CD147, IT'S AGONIST AND APPLICATION |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005508141A (en) * | 2001-05-25 | 2005-03-31 | セローノ ジェネティクス インスティテュート ソシエテ アニニム | Human cDNAs and proteins and their use |
-
2004
- 2004-03-25 CA CA002560903A patent/CA2560903A1/en not_active Abandoned
- 2004-03-25 WO PCT/US2004/009151 patent/WO2005092381A1/en active Application Filing
- 2004-03-25 JP JP2007504930A patent/JP2007530538A/en not_active Withdrawn
- 2004-03-25 AU AU2004317548A patent/AU2004317548A1/en not_active Abandoned
- 2004-03-25 EP EP04821758A patent/EP1732599A4/en not_active Withdrawn
- 2004-03-25 CN CNA200480043088XA patent/CN1960753A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999045031A2 (en) * | 1998-03-03 | 1999-09-10 | Abgenix, Inc. | Cd147 binding molecules as therapeutics |
WO2002013763A2 (en) * | 2000-08-10 | 2002-02-21 | The Picower Institute For Medical Research | Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists |
WO2002094875A1 (en) * | 2001-05-25 | 2002-11-28 | Zhinan Chen | HAb18G/CD147, IT'S AGONIST AND APPLICATION |
EP1403284A1 (en) * | 2001-05-25 | 2004-03-31 | Chen, Zhinan | HAb18G/CD147, IT'S AGONIST AND APPLICATION |
Non-Patent Citations (4)
Title |
---|
See also references of WO2005092381A1 * |
SHANG P ET AL: "Inhibitory Effects of Antisense RNA of HA18G/CD147 on Invasion of hepatocellular Carcinoma Cells in vitro", WORLD JOURNAL OF GASTROENTEROLOGY, XX, XX, vol. 9, no. 10, 2003, pages 2174 - 2177, XP003005123, ISSN: 1007-9327 * |
SHANG P, QIAN A R, HU P Z, MA F C, ZHU P, CHEN Z N: "The influences of HAb18G/CD147's antagonistic peptides on angiogenesis in vivo", CHINESE PHARMACOLOGICAL BULLETIN, vol. 19, no. 3, March 2003 (2003-03-01), pages 355 - 357, XP008089960 * |
ZUCKER S ET AL: "Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment.", ONCOGENE 27 DEC 2000, vol. 19, no. 56, 27 December 2000 (2000-12-27), pages 6642 - 6650, XP002474900, ISSN: 0950-9232 * |
Also Published As
Publication number | Publication date |
---|---|
CA2560903A1 (en) | 2005-10-06 |
EP1732599A1 (en) | 2006-12-20 |
WO2005092381A1 (en) | 2005-10-06 |
CN1960753A (en) | 2007-05-09 |
AU2004317548A1 (en) | 2005-10-06 |
JP2007530538A (en) | 2007-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20061023 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: LT LV |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: TANG, YI Inventor name: YAN, LI Inventor name: NAKADA, MARIAN |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: CENTOCOR, INC. |
|
RAX | Requested extension states of the european patent have changed |
Extension state: LV Payment date: 20061023 Extension state: LT Payment date: 20061023 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20080415 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07K 16/28 20060101ALN20080407BHEP Ipc: A61P 35/00 20060101ALI20080407BHEP Ipc: A61K 39/395 20060101AFI20051012BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080715 |