EP1732555A4 - Opioid delivery system - Google Patents

Opioid delivery system

Info

Publication number
EP1732555A4
EP1732555A4 EP04761742A EP04761742A EP1732555A4 EP 1732555 A4 EP1732555 A4 EP 1732555A4 EP 04761742 A EP04761742 A EP 04761742A EP 04761742 A EP04761742 A EP 04761742A EP 1732555 A4 EP1732555 A4 EP 1732555A4
Authority
EP
European Patent Office
Prior art keywords
delivery system
opioid delivery
opioid
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04761742A
Other languages
German (de)
French (fr)
Other versions
EP1732555A1 (en
Inventor
Orlando Ricardo Hung
Steven Louis Shafer
Diana Helen Pliura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead YM ULC
Original Assignee
YM Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/788,466 external-priority patent/US7648981B2/en
Priority claimed from PCT/CA2004/000303 external-priority patent/WO2004075879A1/en
Application filed by YM Biosciences Inc filed Critical YM Biosciences Inc
Publication of EP1732555A1 publication Critical patent/EP1732555A1/en
Publication of EP1732555A4 publication Critical patent/EP1732555A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP04761742A 2003-02-28 2004-08-27 Opioid delivery system Withdrawn EP1732555A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45033303P 2003-02-28 2003-02-28
US10/788,466 US7648981B2 (en) 2003-02-28 2004-03-01 Opioid delivery system
PCT/CA2004/000303 WO2004075879A1 (en) 2003-02-28 2004-03-01 Opioid delivery system
PCT/CA2004/001578 WO2005082369A1 (en) 2003-02-28 2004-08-27 Opioid delivery system

Publications (2)

Publication Number Publication Date
EP1732555A1 EP1732555A1 (en) 2006-12-20
EP1732555A4 true EP1732555A4 (en) 2008-07-16

Family

ID=42354335

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04761742A Withdrawn EP1732555A4 (en) 2003-02-28 2004-08-27 Opioid delivery system

Country Status (6)

Country Link
EP (1) EP1732555A4 (en)
KR (1) KR20070011344A (en)
CN (1) CN1938027A (en)
AU (1) AU2004316339A1 (en)
NO (1) NO20064463L (en)
WO (1) WO2005082369A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101472631A (en) * 2006-06-21 2009-07-01 伯尔尼大学 A system for controlling administration of anaesthesia
KR20220126409A (en) 2021-03-09 2022-09-16 주식회사 퍼넥티브 Non-face-to-face English education platform and foreign language learning method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007333A1 (en) * 1989-01-06 1990-07-12 Riker Laboratories, Inc. Fentanyl containing aerosol compositions
US5451408A (en) * 1994-03-23 1995-09-19 Liposome Pain Management, Ltd. Pain management with liposome-encapsulated analgesic drugs
US5910301A (en) * 1994-05-13 1999-06-08 Aradigm Corporation Method of intrapulmonary administration of a narcotic drug
US20010007665A1 (en) * 1996-03-23 2001-07-12 Lisbeth Illum Polysaccharide microspheres for the pulmonary delivery of drugs
US20030017119A1 (en) * 2001-05-24 2003-01-23 Rabinowitz Joshua D. Delivery of opioids through an inhalation route
US20030015197A1 (en) * 2001-06-05 2003-01-23 Hale Ron L. Method of forming an aerosol for inhalation delivery

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007333A1 (en) * 1989-01-06 1990-07-12 Riker Laboratories, Inc. Fentanyl containing aerosol compositions
US5451408A (en) * 1994-03-23 1995-09-19 Liposome Pain Management, Ltd. Pain management with liposome-encapsulated analgesic drugs
US5910301A (en) * 1994-05-13 1999-06-08 Aradigm Corporation Method of intrapulmonary administration of a narcotic drug
US20010007665A1 (en) * 1996-03-23 2001-07-12 Lisbeth Illum Polysaccharide microspheres for the pulmonary delivery of drugs
US20030017119A1 (en) * 2001-05-24 2003-01-23 Rabinowitz Joshua D. Delivery of opioids through an inhalation route
US20030015197A1 (en) * 2001-06-05 2003-01-23 Hale Ron L. Method of forming an aerosol for inhalation delivery

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATHER LAURENCE E ET AL: "Pulmonary administration of aerosolised fentanyl: Pharmacokinetic analysis of systemic delivery", BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, vol. 46, no. 1, July 1998 (1998-07-01), pages 37 - 43, XP002283559, ISSN: 0306-5251 *
See also references of WO2005082369A1 *

Also Published As

Publication number Publication date
AU2004316339A1 (en) 2005-09-09
EP1732555A1 (en) 2006-12-20
KR20070011344A (en) 2007-01-24
NO20064463L (en) 2006-11-30
WO2005082369A1 (en) 2005-09-09
CN1938027A (en) 2007-03-28

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20060928

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: LT LV

RAX Requested extension states of the european patent have changed

Extension state: LV

Payment date: 20061002

Extension state: LT

Payment date: 20061002

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: YM BIOSCIENCES INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20080616

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/4748 20060101ALI20080610BHEP

Ipc: A61K 9/12 20060101AFI20080610BHEP

Ipc: A61P 25/04 20060101ALI20080610BHEP

17Q First examination report despatched

Effective date: 20080911

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120301