EP1679308A4 - Novel indazole derivative - Google Patents
Novel indazole derivativeInfo
- Publication number
- EP1679308A4 EP1679308A4 EP04792805A EP04792805A EP1679308A4 EP 1679308 A4 EP1679308 A4 EP 1679308A4 EP 04792805 A EP04792805 A EP 04792805A EP 04792805 A EP04792805 A EP 04792805A EP 1679308 A4 EP1679308 A4 EP 1679308A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- alkyl
- hydrogen
- halogeno
- aryloxy
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12160543.0A EP2468729B1 (en) | 2003-10-15 | 2004-10-15 | Novel indazole derivative |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003354917 | 2003-10-15 | ||
JP2004270561 | 2004-08-20 | ||
PCT/JP2004/015663 WO2005035506A1 (en) | 2003-10-15 | 2004-10-15 | Novel indazole derivative |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12160543.0 Division-Into | 2012-03-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1679308A1 EP1679308A1 (en) | 2006-07-12 |
EP1679308A4 true EP1679308A4 (en) | 2009-06-03 |
EP1679308B1 EP1679308B1 (en) | 2013-07-24 |
Family
ID=34436941
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12160543.0A Not-in-force EP2468729B1 (en) | 2003-10-15 | 2004-10-15 | Novel indazole derivative |
EP04792805.6A Not-in-force EP1679308B1 (en) | 2003-10-15 | 2004-10-15 | Novel indazole derivative |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12160543.0A Not-in-force EP2468729B1 (en) | 2003-10-15 | 2004-10-15 | Novel indazole derivative |
Country Status (9)
Country | Link |
---|---|
US (3) | US7563906B2 (en) |
EP (2) | EP2468729B1 (en) |
JP (2) | JP4110324B2 (en) |
KR (1) | KR101163800B1 (en) |
CN (1) | CN1863779B (en) |
CA (1) | CA2542609C (en) |
ES (1) | ES2426288T3 (en) |
TW (1) | TWI344961B (en) |
WO (1) | WO2005035506A1 (en) |
Families Citing this family (97)
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TWI344961B (en) * | 2003-10-15 | 2011-07-11 | Ube Industries | Novel indazole derivative |
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US20090029970A1 (en) * | 2005-02-16 | 2009-01-29 | Astellas Pharma Inc. | Pain remedy containing rock inhibitor |
RU2414904C2 (en) | 2005-03-31 | 2011-03-27 | Асахи Гласс Компани, Лимитед | PROTECTIVE MEDICIATION FOR RETINA NEURON WHICH CONTAINS AS ACTIVE COMPONETS PROSTAGLANDIN F2α DERIVATIVE |
RU2392938C2 (en) * | 2005-04-13 | 2010-06-27 | Убе Индастриз, Лтд | Protective agent for neural retina cells containing indazole derivatives as active ingredient |
ES2393768T3 (en) * | 2005-05-26 | 2012-12-27 | Neuron Systems, Inc | Quinoline derivative for the treatment of retinal diseases |
US8008317B2 (en) | 2005-06-10 | 2011-08-30 | Merck Sharp & Dohme Corp. | Inhibitors of akt activtiy |
WO2006137368A1 (en) | 2005-06-21 | 2006-12-28 | Kowa Co., Ltd. | Preventive or remedy for glaucoma |
US8343953B2 (en) | 2005-06-22 | 2013-01-01 | Astex Therapeutics Limited | Pharmaceutical compounds |
EP1933832A2 (en) | 2005-06-23 | 2008-06-25 | Astex Therapeutics Limited | Pharmaceutical combinations comprising pyrazole derivatives as protein kinase modulators |
EP1910297B1 (en) | 2005-07-11 | 2016-05-25 | Aerie Pharmaceuticals, Inc. | Isoquinoline compounds |
US20070135499A1 (en) * | 2005-07-11 | 2007-06-14 | Aerie Pharmaceuticals, Inc. | Hydrazide compounds |
PL1905452T3 (en) | 2005-07-12 | 2013-11-29 | Kowa Co | Agent for prevention or treatment of glaucoma |
EP1932841B1 (en) | 2005-08-30 | 2014-01-01 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
KR20080040027A (en) | 2005-09-02 | 2008-05-07 | 아스테라스 세이야쿠 가부시키가이샤 | Amide derivatives as rock inhibitors |
US8008481B2 (en) * | 2006-03-31 | 2011-08-30 | Ericsson Anna M | Indazole compounds |
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WO2008036540A2 (en) | 2006-09-20 | 2008-03-27 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
AR064010A1 (en) | 2006-12-06 | 2009-03-04 | Merck & Co Inc | AKT ACTIVITY INHIBITORS |
US20100022517A1 (en) * | 2006-12-18 | 2010-01-28 | Richards Lori A | Ophthalmic formulation of rho kinase inhibitor compound |
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DE102007002717A1 (en) | 2007-01-18 | 2008-07-24 | Merck Patent Gmbh | Heterocyclic indazole derivatives |
US8415372B2 (en) | 2007-02-27 | 2013-04-09 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
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GB0704932D0 (en) | 2007-03-14 | 2007-04-25 | Astex Therapeutics Ltd | Pharmaceutical compounds |
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ES2566339T3 (en) * | 2008-06-05 | 2016-04-12 | Glaxo Group Limited | 4-Carboxamide indazole derivatives useful as PI3-kinase inhibitors |
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-
2004
- 2004-10-15 TW TW093131357A patent/TWI344961B/en not_active IP Right Cessation
- 2004-10-15 ES ES04792805T patent/ES2426288T3/en active Active
- 2004-10-15 KR KR1020067006900A patent/KR101163800B1/en not_active IP Right Cessation
- 2004-10-15 WO PCT/JP2004/015663 patent/WO2005035506A1/en active Application Filing
- 2004-10-15 CA CA2542609A patent/CA2542609C/en not_active Expired - Fee Related
- 2004-10-15 EP EP12160543.0A patent/EP2468729B1/en not_active Not-in-force
- 2004-10-15 CN CN2004800287044A patent/CN1863779B/en not_active Expired - Fee Related
- 2004-10-15 US US10/575,645 patent/US7563906B2/en not_active Expired - Fee Related
- 2004-10-15 EP EP04792805.6A patent/EP1679308B1/en not_active Not-in-force
- 2004-10-15 JP JP2005514698A patent/JP4110324B2/en active Active
-
2008
- 2008-01-28 JP JP2008015873A patent/JP4922955B2/en not_active Expired - Fee Related
-
2009
- 2009-06-19 US US12/456,652 patent/US7855222B2/en not_active Expired - Fee Related
-
2010
- 2010-10-20 US US12/925,367 patent/US8232308B2/en not_active Expired - Fee Related
Non-Patent Citations (1)
Title |
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No further relevant documents disclosed * |
Also Published As
Publication number | Publication date |
---|---|
CA2542609A1 (en) | 2005-04-21 |
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CN1863779B (en) | 2010-05-05 |
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EP2468729B1 (en) | 2013-12-25 |
US7563906B2 (en) | 2009-07-21 |
US8232308B2 (en) | 2012-07-31 |
JP2008143913A (en) | 2008-06-26 |
TW200524896A (en) | 2005-08-01 |
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