EP1651760A4 - Human blood proteins expressed in monocot seeds - Google Patents

Human blood proteins expressed in monocot seeds

Info

Publication number
EP1651760A4
EP1651760A4 EP03714394A EP03714394A EP1651760A4 EP 1651760 A4 EP1651760 A4 EP 1651760A4 EP 03714394 A EP03714394 A EP 03714394A EP 03714394 A EP03714394 A EP 03714394A EP 1651760 A4 EP1651760 A4 EP 1651760A4
Authority
EP
European Patent Office
Prior art keywords
human blood
proteins expressed
blood proteins
monocot seeds
monocot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03714394A
Other languages
German (de)
French (fr)
Other versions
EP1651760A1 (en
Inventor
Ning Huang
Raymond L Rodriquez
Frank E Hagie
David M Stalker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invitria Inc
Original Assignee
Ventria Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventria Bioscience Inc filed Critical Ventria Bioscience Inc
Publication of EP1651760A1 publication Critical patent/EP1651760A1/en
Publication of EP1651760A4 publication Critical patent/EP1651760A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP03714394A 2003-04-11 2003-04-11 Human blood proteins expressed in monocot seeds Withdrawn EP1651760A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/009209 WO2004099405A1 (en) 2003-04-11 2003-04-11 Human blood proteins expressed in monocot seeds

Publications (2)

Publication Number Publication Date
EP1651760A1 EP1651760A1 (en) 2006-05-03
EP1651760A4 true EP1651760A4 (en) 2006-10-18

Family

ID=33434296

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03714394A Withdrawn EP1651760A4 (en) 2003-04-11 2003-04-11 Human blood proteins expressed in monocot seeds

Country Status (5)

Country Link
EP (1) EP1651760A4 (en)
JP (1) JP2006522585A (en)
AU (1) AU2003218396B2 (en)
CA (1) CA2525493C (en)
WO (1) WO2004099405A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003297781A1 (en) * 2003-12-23 2005-08-03 Ventria Bioscience Methods of expressing heterologous protein in plant seeds using monocot non seed-storage protein promoters
WO2006108830A2 (en) * 2005-04-13 2006-10-19 Bayer Cropscience Sa TRANSPLASTOMIC PLANTS EXPRESSING α 1-ANTITRYPSIN
EP2016181B1 (en) 2006-05-12 2013-04-17 Monsanto Technology, LLC Methods and compositions for obtaining marker-free transgenic plants
WO2010004004A1 (en) * 2008-07-09 2010-01-14 Profibrix Bv Recombinant fibrinogen
CN102127164B (en) 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 Method for extracting recombinant human serum albumin from rice seeds
CN102532254B (en) 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 Method for separating and purifying recombinant human serum albumin (rHSA) from rice seeds
CN102994514B (en) * 2012-11-07 2015-06-10 武汉禾元生物科技股份有限公司 Method for producing, separating and purifying recombinant human antitrypsin (OsrAAT) from rice seeds
CN103880947B (en) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 A kind of chromatography method of separating and purifying high-purity recombination human serum albumin
ES2791364T3 (en) * 2013-09-11 2020-11-04 Impossible Foods Inc Secretion of heme-containing polypeptides
EP3294762B1 (en) 2015-05-11 2022-01-19 Impossible Foods Inc. Expression constructs and methods of genetically engineering methylotrophic yeast
CN109355291B (en) * 2018-11-22 2022-01-18 深圳市作物分子设计育种研究院 Identification and application of plant endosperm specific expression promoter pOsEnS93
EP3956454A1 (en) 2019-04-17 2022-02-23 Impossible Foods Inc. Materials and methods for protein production
KR20220004090A (en) 2019-04-25 2022-01-11 임파서블 푸즈 인크. Strains and methods for the production of heme-containing proteins
WO2024003668A1 (en) * 2022-06-29 2024-01-04 Moolec Science Limited High expression of animal heme protein in plants

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344600B1 (en) * 1995-07-17 2002-02-05 Meristem Therapeutics Method for producing human hemoglobin proteins using plant cells
WO2002064750A2 (en) * 2001-02-14 2002-08-22 Ventria Bioscience Expression system for seed proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693506A (en) * 1993-11-16 1997-12-02 The Regents Of The University Of California Process for protein production in plants

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344600B1 (en) * 1995-07-17 2002-02-05 Meristem Therapeutics Method for producing human hemoglobin proteins using plant cells
WO2002064750A2 (en) * 2001-02-14 2002-08-22 Ventria Bioscience Expression system for seed proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HUANG J ET AL: "Expression and purification of functional human alpha-1-antitrypsin from cultured plant cells", BIOTECHNOLOGY PROGRESS, XX, XX, vol. 17, no. 1, 30 December 2000 (2000-12-30), pages 126 - 133, XP002367520, ISSN: 8756-7938 *
See also references of WO2004099405A1 *

Also Published As

Publication number Publication date
AU2003218396B2 (en) 2008-09-04
CA2525493A1 (en) 2004-11-18
WO2004099405A1 (en) 2004-11-18
AU2003218396A1 (en) 2004-11-26
EP1651760A1 (en) 2006-05-03
JP2006522585A (en) 2006-10-05
CA2525493C (en) 2018-10-30

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Legal Events

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Effective date: 20060919

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