EP1649889A1 - Catheter particularly for insertion of pace-maker or ICD-electrodes into a patient's body - Google Patents

Catheter particularly for insertion of pace-maker or ICD-electrodes into a patient's body Download PDF

Info

Publication number
EP1649889A1
EP1649889A1 EP05022550A EP05022550A EP1649889A1 EP 1649889 A1 EP1649889 A1 EP 1649889A1 EP 05022550 A EP05022550 A EP 05022550A EP 05022550 A EP05022550 A EP 05022550A EP 1649889 A1 EP1649889 A1 EP 1649889A1
Authority
EP
European Patent Office
Prior art keywords
catheter
profile part
axial
catheter according
webs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05022550A
Other languages
German (de)
French (fr)
Other versions
EP1649889B1 (en
Inventor
Erhard Flach
Wolfgang Dr. Geistert
Michelle Maxfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotronik CRM Patent AG
Original Assignee
Biotronik CRM Patent AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotronik CRM Patent AG filed Critical Biotronik CRM Patent AG
Publication of EP1649889A1 publication Critical patent/EP1649889A1/en
Application granted granted Critical
Publication of EP1649889B1 publication Critical patent/EP1649889B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode

Definitions

  • cardiac pacemaker or ICD implantable cardioverter defibrillator
  • Such catheters are known to comprise at least one lumen which is bounded by the catheter wall and serves to guide the electrode to be inserted after insertion of the catheter into the patient's body.
  • the catheter can be pushed over a further lumen, for example, over a guide wire previously applied in the patient's body or equipped with a puller wire for the catheter tip.
  • catheters have a slit or tearable catheter wall along their longitudinal axial direction so that they can be easily removed therefrom upon placement of the electrode in the patient's body.
  • a catheter is shown in EP 0 655 257 A2, which discloses a line of weakness in the form of a perforation in the catheter wall.
  • EP 0 898 481 B1 US Pat. No. 6,159,198 and WO 99/33509 A1 disclose in this connection the insertion of reinforcing fibers into the catheter wall. These can be applied as individual fibers, as shown in WO 99/33509 A1 and EP 0 898 481 B1, or as a mesh tube, as is apparent from US Pat. No. 6,159,198.
  • the present invention seeks to improve a catheter so that in a simple manner both in the axial and in the peripheral direction changing mechanical properties, such as torsion, bending, buckling stability, compressibility, flexibility and slitability can be generated.
  • the gain form as a profile part, which is tuned in the axial and peripheral direction of the catheter on the mechanical properties of the shell.
  • the gain form is specified in the characterizing part of claim 1 and provides in their basic expression, the gain form as a profile part, which is tuned in the axial and peripheral direction of the catheter on the mechanical properties of the shell.
  • buckling resistance and compressive strength can be achieved. It is therefore advantageously no longer necessary - as is also known from the prior art - to set different different catheter shaft pieces together in the axial and / or peripheral direction of changing properties and to glue or weld them together.
  • a slittability of the catheter can, for. B. be made by a made on the peripheral direction Wanddickeneinschnürung the profile part.
  • the catheter 1 shown in Fig. 1 has a catheter wall 2, which is constructed radially from the inside to the outside by an inner tube 3, an outer tube 4 and a profile part 5 lying therebetween.
  • inner tube 3 two extending from the proximal to the distal end (each not shown) of the catheter 1 lumen 6, 6 'are applied, through which, for example, a pacemaker electrode and a pull wire are pushed through.
  • Inner and outer tube 3, 4 are made of an extruded elastomeric material, as is common for use in medical tubing and tubes.
  • the profile part 5 is designed as a longitudinally cylindrical lattice profile part, which in the illustrated region is divided into partial lengths t1, t2, t3, t4 and t5 with different profiling.
  • axial webs 8 extending in the axial direction A through apertures 7 and peripheral webs 9 extending in the peripheral direction P are formed.
  • the profile part in different partial lengths t1 to t5 be designed so that it is tailored to the mechanical properties of the catheter.
  • the torsional and bending resistance of the catheter 1 over the partial length t1 can be significantly reduced compared to the partial length t2.
  • only very thin and short peripheral webs 9 can be left standing between two rows of openings 7, whereby these then form a predetermined breaking point for severing the catheter 1 and removing it from the inserted electrode.
  • a "mixed form" of axial and peripheral webs can be realized by oblique diagonal webs.
  • the profile part is not provided with openings 7, that is cylindrical, whereby it is very stable to compression.
  • the part length t4 a range of elongated openings 7, which form parallel to each other axial webs 8 between them.
  • the profile part 5 is relatively torsionally unstable, so it can be easily twisted in itself.
  • the grating profile part 5 according to FIG. 1 can be produced in various ways.
  • a laser cutting, punching or etching of a tube, tube or flat material, such as a piece of film is possible.
  • the profiled in the flat state piece of material is then rolled and wound as a profile part, for example on the inner tube 3.
  • a production as injection-molded, extruded or similarly hot-formed tube or tube is conceivable.
  • the above semifinished products may be made of plastic material such as polycarbonate, polyimide and the like or of a metal material such as nitinol or stainless steel.
  • the grid profile part 5 thus produced as a semi-finished product can be embedded between the inner and outer tubes 3, 4 after its production by gluing, shrinking or melting. A direct injection into a one-piece hose wall is possible.
  • the grating profile part 5 can also be produced by coating the inner tube 3 with a UV or laser light or chemically hardenable plastic by a kind of lithographic process.
  • a mask is placed on the coating, which is a negative of the desired grid profile.
  • a chemical hardener - such as by dipping or spraying - the coating is cured at the exposed, vacant from the mask by crosslinking and then removed the mask.
  • the uncured zones of the coating can be washed out with a suitable solvent and the grid profile part 5 with the desired pattern of holes remains.
  • the outer tube 4 is then shrunk over the profile part 5 thus produced with inner tube 3, glued or extruded.
  • the above masking can be omitted if the coating is scanned with a scanner laser or focused UV light in the zones to be cured and crosslinked there.
  • the profile part 1 can also be produced by printing the inner tube 3 with a "web image" of a curable material such as a corresponding printing paste, and then curing the material by radiation or chemical crosslinking.
  • a curable material such as a corresponding printing paste
  • an inner tube 3 having two lumens 6, 6', an outer tube 4 and a profile part 5 'located therebetween are provided.
  • the latter is provided with a deviating from the embodiment of FIG. 1 profiling on its partial lengths t1 to t4.
  • Characteristic in this embodiment is the design of the profile part 5 'to the effect that the catheter 1' defined on these partial lengths t1 to t4 is particularly well bendable in certain planes.
  • gore-shaped openings 7 are provided which form between them peripheral webs 9 with hourglass-shaped width profile.
  • the peripheral webs 9 are interconnected by two opposite axial webs 8.
  • the gore-shaped openings 7 are offset by 90 ° relative to those on the partial length t1 and arranged at a greater distance from one another.
  • the catheter is stiff on this partial length t2 in the plane of the drawing in FIG. 2, but is easily bendable for a deflection movement out of the plane of the drawing. Due to the larger distance the openings 7 with respect to part length t1 but the overall flexibility is lower.
  • the lattice structure of the profile part 5" is applied directly in the inner tube 3.
  • the latter again has two lumens 6, 6 'and is provided on its surface with a hatched highlighted in Fig. 2, a total of a grid structure with axial and peripheral webs 8, 9 forming reinforcement.
  • a curable material is used for the inner tube 3, which is irradiated in the hatched in Fig. 3 zones and thereby cured. A removal of the non-irradiated zones can be omitted, so that despite the integrated reinforcement, the component has a flat surface.
  • an outer tube 4 is applied in the manner discussed.
  • FIG. 4 Another embodiment of a catheter 1 '' 'is finally shown in Figs. 4 and 5.
  • this embodiment does not differ from that shown in FIG. 1.
  • the profile part 5 '' ' is made in one piece from a hard plastic material, such as polycarbonate or polyimide, or from thin metal material, such as stainless steel or Nitinol, and has on the partial lengths t1, t2 and t4 parallel spaced apart peripheral webs on. These are designed as partial rings whose ends 11 are each connected to each other by an axially continuous axial web 8, 8 '. Between the two axial webs 8, 8 'remains a gap 12, which serves in the catheter 1' '' as a predetermined breaking point for its separation for removal from the inserted electrode.
  • the openings 7 and in particular peripheral webs 9 are designed differently on the different partial lengths t1 to t4.
  • the partial length t1 arranged towards the distal end relatively thin peripheral webs 9 are provided, so that the catheter is relatively flexible there.
  • the peripheral webs 9 are significantly widened, as a result of which the flexibility decreases.
  • peripheral webs 9 are separated from each other by axially wide openings 7, so that the catheter is there very flexible in the plane passing through the gap 12 center plane.
  • Fig. 5 the profile part 5 '' 'is shown on its part length t1 without inner and outer tube.
  • the profile parts can be made of a material that is compatible for MR viewing devices or detectable in ultrasound or X-ray devices.

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The catheter has a catheter wall (2), which defines one of lumens (6, 6), and a reinforcement provided in an axial and peripheral direction (A, P) in the catheter wall. The reinforcement is provided for stabilization of the catheter in torsional and/or buckling strength. The reinforcement is designed as a profile unit (5), which is adjusted to desired mechanical properties of the catheter in the axial and peripheral direction.

Description

Die Erfindung betrifft einen Katheter insbesondere zur Einführung von Herzschrittmacher- oder ICD-(= Implantible cardioverter defibrillator-) Elektroden in einen Patientenkörper mit einer Katheterwand und einer Verstärkung darin.The invention relates to a catheter, in particular for introducing cardiac pacemaker or ICD (= implantable cardioverter defibrillator) electrodes into a patient's body having a catheter wall and a reinforcement therein.

Derartige Katheter umfassen bekanntermaßen mindestens ein Lumen, das von der Katheterwand umgrenzt wird und zur Führung der nach dem Einschieben des Katheters in den Patientenkörper einzusetzenden Elektrode dient. Über ein weiteres Lumen kann der Katheter beispielsweise über einen vorher im Patientenkörper applizierten Führungsdraht geschoben oder mit einem Zugdraht für die Katheterspitze ausgerüstet werden.Such catheters are known to comprise at least one lumen which is bounded by the catheter wall and serves to guide the electrode to be inserted after insertion of the catheter into the patient's body. The catheter can be pushed over a further lumen, for example, over a guide wire previously applied in the patient's body or equipped with a puller wire for the catheter tip.

Ferner ist es bekannt, dass derartige Katheter entlang ihrer Längsaxialrichtung eine schlitz- oder aufreißbare Katheterwand aufweisen, so dass sie nach Platzierung der Elektrode im Patientenkörper einfach davon entfernt werden können. Einen solchen Katheter zeigt die EP 0 655 257 A2, die eine Schwächungslinie in Form einer Perforation in der Katheterwand offenbart.Further, it is known that such catheters have a slit or tearable catheter wall along their longitudinal axial direction so that they can be easily removed therefrom upon placement of the electrode in the patient's body. Such a catheter is shown in EP 0 655 257 A2, which discloses a line of weakness in the form of a perforation in the catheter wall.

Ein gängiges Problem bei solchen Kathetern liegt schließlich in der Torsions- und Knickstabilität des Katheterschaftes und dessen Kompressionsempfindlichkeit, insbesondere wenn der Katheter in einem kleinen Radius gebogen werden muss, wie die beispielsweise beim Einführen in die Arteria subclavia der Fall ist.Finally, a common problem with such catheters resides in the torsional and kinking stability of the catheter shaft and its compression sensitivity, especially when the catheter has to be bent in a small radius, as is the case, for example, when inserted into the subclavian artery.

Aus dem Stand der Technik ist es zur Lösung dieser Problematik bereits bekannt, Verstärkungen in der Katheterwand vorzusehen, mit deren Hilfe der Katheter bezüglich seiner Torsions- und/oder Knicksteifigkeit und gegen ungewünschte Komprimierung stabilisiert wird. Die EP 0 898 481 B1, US 6 159 198 A und WO 99/33509 A1 offenbaren in diesem Zusammenhang die Einlage von Verstärkungsfasern in die Katheterwand. Diese können als Einzelfasern, wie in der WO 99/33509 A1 und der EP 0 898 481 B1 gezeigt, oder als Netzschlauch angelegt sein, wie dies aus der US 6 159 198 A hervorgeht.It is already known from the prior art to solve this problem, to provide reinforcements in the catheter wall, with the help of which the catheter is stabilized with respect to its torsional and / or bending stiffness and against undesired compression. EP 0 898 481 B1, US Pat. No. 6,159,198 and WO 99/33509 A1 disclose in this connection the insertion of reinforcing fibers into the catheter wall. These can be applied as individual fibers, as shown in WO 99/33509 A1 and EP 0 898 481 B1, or as a mesh tube, as is apparent from US Pat. No. 6,159,198.

Wenngleich durch die eingelegten Fasern das Ziel einer Verstärkung grundsätzlich erreichbar ist, verursachen derartige Fasereinlagen einige Probleme insbesondere hinsichtlich der Katheterfertigung. Zwar ist die Einlage von Faserverstärkungen in Form einer Netz- oder Litzenstruktur in Schlauchgebilde grundsätzlich ein übliches Produktionsverfahren, jedoch können solche Faserverstärkungen nur schwer in Axial- und Peripherrichtung an bestimmte Solleigenschaften angepasst werden. Dies trifft insbesondere auch für die Schwächung des Katheters zur Bildung einer Aufreißlinie zu. Die erwähnte EP 0 898 481 B1 zeigt in diesem Zusammenhang eine Perforationslinie, die die in Peripherrichtung in der Katheterwand verlaufenden Verstärkungsfasern jeweils nur anreißt. Eine Umsetzung dieser dort schematisch dargestellten Maßnahme in die Praxis dürfte nur mit erheblichem Fertigungsaufwand möglich sein. Dies trifft umso mehr auf die ebenfalls in der vorgenannten Druckschrift gezeigten Verstärkungsfasern mit stark flach-rechteckigem Querschnitt zu, bei denen bei zu tiefen Ansetzen der Perforationslinien eine Durchtrennung der Verstärkungsfasern zu befürchten ist.Although the objective of reinforcement is basically achievable by the inserted fibers, such fiber inserts cause some problems, in particular with regard to catheter fabrication. Although the incorporation of fiber reinforcements in the form of a net or stranded structure in tubular structures is basically a common production method, however, such fiber reinforcements are difficult to adapt in the axial and peripheral directions to certain nominal properties. This is especially true for the weakening of the catheter to form a tear line. The mentioned EP 0 898 481 B1 shows in this connection a perforation line which only tears the reinforcing fibers running in the peripheral direction in the catheter wall in each case only. An implementation of this measure schematically illustrated in practice is likely to be possible only with considerable manufacturing effort. This applies all the more to the reinforcing fibers with a flat-rectangular cross-section which are likewise shown in the aforementioned publication, in which a severing of the reinforcing fibers is to be feared if the perforation lines are set too low.

Ausgehend von den geschilderten Problemen des Standes der Technik liegt der Erfindung die Aufgabe zugrunde, einen Katheter so zu verbessern, dass auf einfache Weise sowohl in axialer als auch in peripherer Richtung wechselnde mechanische Eigenschaften, wie Torsions-, Biege-, Knickstabilität, Kompressibilität, Flexibilität und Schlitzbarkeit erzeugbar sind.Based on the described problems of the prior art, the present invention seeks to improve a catheter so that in a simple manner both in the axial and in the peripheral direction changing mechanical properties, such as torsion, bending, buckling stability, compressibility, flexibility and slitability can be generated.

Die Lösung dieser Aufgabe ist im Kennzeichnungsteil des Anspruches 1 angegeben und sieht in ihrer grundsätzlichen Ausprägung vor, die Verstärkung als Profilteil auszubilden, das in Axial- und Peripherrichtung des Katheters auf dessen mechanische Solleigenschaften abgestimmt ist. So kann beispielsweise durch die sich ändernde Wandstärke des Profilteils eine über die Länge des Katheters wechselnde Flexibilität, Knicksteifigkeit und Kompressionsfestigkeit erzielt werden. Es ist also vorteilhafterweise nicht mehr notwendig - wie dies ebenfalls aus dem Stand der Technik bekannt ist - zur Erzeugung in axialer und/oder peripherer Richtung wechselnder Eigenschaften verschiedene unterschiedliche Katheterschaft-Stücke aneinander zu setzen und miteinander zu verkleben oder zu verschweißen. Eine Schlitzbarkeit des Katheters kann z. B. durch eine bezogen auf die Peripherrichtung vorgenommene Wanddickeneinschnürung des Profilteils hergestellt werden.The solution to this problem is specified in the characterizing part of claim 1 and provides in their basic expression, the gain form as a profile part, which is tuned in the axial and peripheral direction of the catheter on the mechanical properties of the shell. Thus, for example, by the changing wall thickness of the profile part over the length of the catheter changing flexibility, buckling resistance and compressive strength can be achieved. It is therefore advantageously no longer necessary - as is also known from the prior art - to set different different catheter shaft pieces together in the axial and / or peripheral direction of changing properties and to glue or weld them together. A slittability of the catheter can, for. B. be made by a made on the peripheral direction Wanddickeneinschnürung the profile part.

Bevorzugte Ausführungsformen der Erfindung sind in den Unteransprüchen angegeben. Weitere Merkmale, Einzelheiten und Vorteile der Erfindung gehen im Übrigen aus der folgenden Beschreibung hervor, in der Ausführungsbeispiele anhand der beigefügten Zeichnungen näher erläutert werden. Es zeigen:

Fig. 1
eine höchst schematische, ausschnittsweise und teilweise weggebrochene Perspektivdarstellung eines Katheters in einer ersten Ausführungsform,
Fig. 2 bis 4
Perspektivdarstellungen analog Fig. 1 dreier weiterer Ausführungsformen des Katheters,
Fig. 5
eine schematische ausschnittsweise Perspektivdarstellung eines in den Katheter gemäß Fig. 4 eingesetzten Profilteils.
Preferred embodiments of the invention are specified in the subclaims. Other features, details and advantages of the invention will become apparent from the following description, are explained in more detail in the embodiments with reference to the accompanying drawings. Show it:
Fig. 1
a highly schematic, partial and partially broken away perspective view of a catheter in a first embodiment,
Fig. 2 to 4
Perspective representations analogous to FIG. 1 of three further embodiments of the catheter,
Fig. 5
a schematic partial perspective view of a profile member used in the catheter of FIG. 4.

Der in Fig. 1 gezeigte Katheter 1 weist eine Katheterwand 2 auf, die radial von innen nach außen durch einen Innenschlauch 3, einen Außenschlauch 4 und ein dazwischen liegendes Profilteil 5 aufgebaut ist. Im Innenschlauch 3 sind zwei vom proximalen zum distalen Ende (jeweils nicht dargestellt) des Katheters 1 verlaufende Lumen 6, 6' angelegt, durch die beispielsweise eine Herzschrittmacher-Elektrode und ein Zugdraht durchschiebbar sind. Innen- und Außenschlauch 3, 4 bestehen aus einem extrudierten Elastomermaterial, wie es zur Anwendung in medizinischen Schläuchen und Röhren gängig ist.The catheter 1 shown in Fig. 1 has a catheter wall 2, which is constructed radially from the inside to the outside by an inner tube 3, an outer tube 4 and a profile part 5 lying therebetween. In the inner tube 3, two extending from the proximal to the distal end (each not shown) of the catheter 1 lumen 6, 6 'are applied, through which, for example, a pacemaker electrode and a pull wire are pushed through. Inner and outer tube 3, 4 are made of an extruded elastomeric material, as is common for use in medical tubing and tubes.

Das Profilteil 5 ist in dem in Fig. 1 gezeigten Ausführungsbeispiel als in der Grundform längszylindrisches Gitterprofilteil ausgebildet, das in dem dargestellten Bereich in Teillängen t1, t2, t3, t4 und t5 mit unterschiedlicher Profilierung gegliedert ist. Grundsätzlich sind durch Öffnungen 7 in seiner Mantelwand in Axialrichtung A verlaufende Axialstege 8 und in Peripherrichtung P verlaufende Peripherstege 9 gebildet. Wie in der Zeichnung angedeutet ist, kann durch eine Variierung der Dicke der Mantelwand des Gitterprofilteils 5, sowie insbesondere der Größe der Öffnungen 7 und/oder der Querschnittsdimensionierung der Axial- und Peripherstege 8, 9 das Profilteil in unterschiedlichen Teillängen t1 bis t5 so ausgelegt werden, dass es auf die mechanischen Solleigenschaften des Katheters abgestimmt ist. Beispielsweise kann durch eine Vergrößerung der Öffnungen 7 jeweils in Richtung zum distalen Ende hin unter entsprechender Verringerung der Breiten der Axial- und Peripherstege 8, 9 der Torsions- und Biegewiderstand des Katheters 1 auf der Teillänge t1 gegenüber der Teillänge t2 deutlich verringert werden. Ferner können ― wie nicht explizit dargestellt ist - zwischen zwei Reihen von Öffnungen 7 nur sehr dünne und kurze Peripherstege 9 stehen gelassen werden, wodurch diese dann eine Sollbruchstelle zum Auftrennen des Katheters 1 und dessen Abnehmen von der eingesetzten Elektrode bilden. Auch kann eine "Mischform" von Axial- und Peripherstegen durch schräg verlaufende Diagonalstege realisiert werden.In the exemplary embodiment shown in FIG. 1, the profile part 5 is designed as a longitudinally cylindrical lattice profile part, which in the illustrated region is divided into partial lengths t1, t2, t3, t4 and t5 with different profiling. In principle, axial webs 8 extending in the axial direction A through apertures 7 and peripheral webs 9 extending in the peripheral direction P are formed. As indicated in the drawing, by a variation of the thickness of the shell wall of the grating profile part 5, and in particular the size of the openings 7 and / or the cross-sectional dimensioning of the axial and peripheral webs 8, 9, the profile part in different partial lengths t1 to t5 be designed so that it is tailored to the mechanical properties of the catheter. For example, by increasing the size of the openings 7 toward the distal end, with a corresponding reduction in the widths of the axial and peripheral webs 8, 9, the torsional and bending resistance of the catheter 1 over the partial length t1 can be significantly reduced compared to the partial length t2. Furthermore, as not explicitly shown, only very thin and short peripheral webs 9 can be left standing between two rows of openings 7, whereby these then form a predetermined breaking point for severing the catheter 1 and removing it from the inserted electrode. Also, a "mixed form" of axial and peripheral webs can be realized by oblique diagonal webs.

Auf der Teillänge t3 ist das Profilteil nicht mit Öffnungen 7 versehen, also zylindrisch ausgeführt, wodurch es sehr kompressionsstabil ist.On the part length t3, the profile part is not provided with openings 7, that is cylindrical, whereby it is very stable to compression.

Es schließt sich auf der Teillänge t4 ein Bereich langgestreckter Öffnungen 7 an, die zwischen sich zueinander parallel Axialstege 8 bilden. In diesem Bereich ist das Profilteil 5 relativ torsionsinstabil, kann also leicht in sich verdrillt werden.This is followed on the part length t4 a range of elongated openings 7, which form parallel to each other axial webs 8 between them. In this area, the profile part 5 is relatively torsionally unstable, so it can be easily twisted in itself.

Auf der Teillänge t5 schließlich ist ein relativ enges Gittermuster von Axial- und Peripherstegen 8, 9 durch enggesetzte Öffnungen 7 angelegt, das das Profilteil 5 in diesem Teil sehr biegsam, allerdings torsionsstabil macht.Finally, on the part length t5, a relatively narrow grid pattern of axial and peripheral webs 8, 9 is applied through narrowed openings 7, which makes the profile part 5 very flexible in this part, albeit torsionally stable.

Das Gitterprofilteil 5 gemäß Fig. 1 kann auf verschiedene Art und Weise hergestellt werden. So ist ein Laserschneiden, Stanzen oder Ätzen aus einem Schlauch, Röhrchen oder Flachmaterial, wie einem Folienstück möglich. Im letztgenannten Fall wird das im flachen Zustand profilierte Materialstück anschließend gerollt und als Profilteil beispielsweise auf den Innenschlauch 3 gewickelt. Auch eine Herstellung als spritzgegossener, extrudierter oder ähnlich heißverformter Schlauch oder Röhrchen ist denkbar.The grating profile part 5 according to FIG. 1 can be produced in various ways. Thus, a laser cutting, punching or etching of a tube, tube or flat material, such as a piece of film is possible. In the latter case, the profiled in the flat state piece of material is then rolled and wound as a profile part, for example on the inner tube 3. A production as injection-molded, extruded or similarly hot-formed tube or tube is conceivable.

Die vorstehenden Halbzeuge können aus Kunststoffmaterial, wie Polycarbonat, Polyimid und dergleichen oder aus einem Metallmaterial, wie Nitinol oder Edelstahl hergestellt sein.The above semifinished products may be made of plastic material such as polycarbonate, polyimide and the like or of a metal material such as nitinol or stainless steel.

Das so als Halbzeug hergestellte Gitterprofilteil 5 kann nach seiner Herstellung durch Kleben, Schrumpfen oder Schmelzen zwischen den Innen- und Außenschlauch 3, 4 eingebettet werden. Auch ein direktes Einspritzen in eine einstückige Schlauchwandung ist möglich.The grid profile part 5 thus produced as a semi-finished product can be embedded between the inner and outer tubes 3, 4 after its production by gluing, shrinking or melting. A direct injection into a one-piece hose wall is possible.

Neben den vorstehenden mechanischen und thermoplastischen Herstellungstechniken kann das Gitterprofilteil 5 auch durch Beschichten des Innenschlauches 3 mit einem in UV- oder Laserlicht oder auch chemisch aushärtbaren Kunststoff durch eine Art lithografisches Verfahren hergestellt werden. Dazu wird auf die Beschichtung eine Maske gelegt, welche ein Negativ der gewünschten Gitterprofilierung darstellt. Durch Bestrahlung oder In-Kontakt-Bringen mit einem chemischen Härter ― etwa durch Tauchen oder Besprühen ― wird die Beschichtung an den exponierten, von der Maske freien Stellen durch Vernetzung ausgehärtet und anschließend die Maske entfernt. Dann können die nicht-ausgehärteten Zonen der Beschichtung mit einem geeigneten Lösungsmittel ausgewaschen werden und das Gitterprofilteil 5 mit dem gewünschten Lochmuster bleibt zurück. Der Außenschlauch 4 wird dann über das so hergestellte Profilteil 5 mit Innenschlauch 3 geschrumpft, geklebt oder extrudiert.In addition to the above mechanical and thermoplastic production techniques, the grating profile part 5 can also be produced by coating the inner tube 3 with a UV or laser light or chemically hardenable plastic by a kind of lithographic process. For this purpose, a mask is placed on the coating, which is a negative of the desired grid profile. By irradiation or contact with a chemical hardener - such as by dipping or spraying - the coating is cured at the exposed, vacant from the mask by crosslinking and then removed the mask. Then the uncured zones of the coating can be washed out with a suitable solvent and the grid profile part 5 with the desired pattern of holes remains. The outer tube 4 is then shrunk over the profile part 5 thus produced with inner tube 3, glued or extruded.

Die vorstehende Maskierung kann dann entfallen, wenn die Beschichtung mit einem Scannerlaser oder fokusierten UV-Licht in den auszuhärtenden Zonen abgescannt und dort vernetzt wird.The above masking can be omitted if the coating is scanned with a scanner laser or focused UV light in the zones to be cured and crosslinked there.

Schließlich kann das Profilteil 1 auch durch Bedrucken des Innenschlauches 3 mit einem "Stegbild" aus einem aushärtbaren Material wie einer entsprechenden Druckpaste, und anschließendem Aushärten des Materials durch Strahlungs- oder chemische Vernetzung hergestellt werden.Finally, the profile part 1 can also be produced by printing the inner tube 3 with a "web image" of a curable material such as a corresponding printing paste, and then curing the material by radiation or chemical crosslinking.

Bei der in Fig. 2 gezeigten Ausführungsform des Katheters 1' sind wiederum ein Innenschlauch 3 mit zwei Lumen 6, 6', ein Außenschlauch 4 und ein dazwischen sitzendes Profilteil 5' vorgesehen. Letzteres ist mit einer von der Ausführungsform gemäß Fig. 1 abweichenden Profilierung auf seinen Teillängen t1 bis t4 versehen. Charakteristisch bei dieser Ausführungsform ist die Auslegung des Profilteils 5' dahingehend, dass der Katheter 1' auf diesen Teillängen t1 bis t4 definiert in bestimmten Ebenen besonders gut biegbar ist. So sind auf der Teillänge t1 auf zwei einander abgewandten Seiten aneinandergereihte, zwickelförmige Öffnungen 7 vorgesehen, die zwischen sich Peripherstege 9 mit sanduhrförmigem Breitenverlauf bilden. Die Peripherstege 9 sind durch zwei gegenüberliegende Axialstege 8 miteinander verbunden. Durch diese Konfiguration ist der Katheter auf der Teillänge t1 besonders gut in der Zeichnungsebene der Fig. 2 biegbar.In the embodiment of the catheter 1 'shown in FIG. 2, in turn, an inner tube 3 having two lumens 6, 6', an outer tube 4 and a profile part 5 'located therebetween are provided. The latter is provided with a deviating from the embodiment of FIG. 1 profiling on its partial lengths t1 to t4. Characteristic in this embodiment is the design of the profile part 5 'to the effect that the catheter 1' defined on these partial lengths t1 to t4 is particularly well bendable in certain planes. Thus, on the part length t1 on two opposite sides juxtaposed, gore-shaped openings 7 are provided which form between them peripheral webs 9 with hourglass-shaped width profile. The peripheral webs 9 are interconnected by two opposite axial webs 8. By this configuration, the catheter on the part length t1 is particularly good in the plane of FIG. 2 bendable.

Auf der Teillänge t2 sind die zwickelförmigen Öffnungen 7 um 90° versetzt gegenüber denjenigen auf der Teillänge t1 und mit größerem Abstand zueinander angeordnet. Dadurch ist der Katheter auf dieser Teillänge t2 in der Zeichnungsebene der Fig. 2 steif, jedoch für eine Auslenkbewegung aus der Zeichnungsebene gut biegbar. Aufgrund des größeren Abstandes der Öffnungen 7 gegenüber Teillänge t1 ist die Biegbarkeit insgesamt jedoch geringer.On the part length t2, the gore-shaped openings 7 are offset by 90 ° relative to those on the partial length t1 and arranged at a greater distance from one another. As a result, the catheter is stiff on this partial length t2 in the plane of the drawing in FIG. 2, but is easily bendable for a deflection movement out of the plane of the drawing. Due to the larger distance the openings 7 with respect to part length t1 but the overall flexibility is lower.

Auf der Teillänge t3 sind aufeinanderfolgende Öffnungen 7 jeweils um 90° versetzt zueinander, sodass eine Art Schräggitter-Profilteil mit schrägverlaufenden Peripherstegen 9 und in Axialrichtung unterbrochenen Axialstegen 8 gebildet wird. Durch den 90°-Versatz aufeinanderfolgender Öffnungen 7 ist der Katheter 1' auf dieser Teillänge t3 flexibel sowohl in der Zeichnungsebene der Fig. 2 als auch senkrecht dazu.On the part length t3 successive openings 7 are each offset by 90 ° to each other, so that a kind of inclined grille profile part with oblique peripheral webs 9 and axially interrupted axial webs 8 is formed. Due to the 90 ° offset of successive openings 7, the catheter 1 'on this part length t3 is flexible both in the plane of the drawing of FIG. 2 and perpendicular thereto.

Auf der Teillänge t4 sind noch wenige Öffnungen 7 mit großem Abstand zueinander vorgesehen, sodass im dortigen Bereich der Katheter 1' sehr steif ist und allenfalls eine geringe Biegbarkeit in der Zeichnungsebene der Fig. 2 (analog Teillänge t1) zeigt.On the part length t4 a few openings 7 are still provided at a great distance from each other, so that in the local area of the catheter 1 'is very stiff and possibly low bendability in the plane of the drawing of FIG. 2 (analog partial length t1) shows.

Hinsichtlich der Herstellung und Einbindung des Profilteils 5' in den Katheteraufbau kann auf die Ausführungen zur Fig. 1 zurückgegriffen werden.With regard to the production and integration of the profile part 5 'in the catheter assembly can be made to the comments on Fig. 1.

Bei der in Fig. 3 dargestellten Ausführungsform des Katheters 1" wird die Gitterstruktur des Profilteils 5" direkt im Innenschlauch 3 angelegt. Letzterer weist im gezeigten Fall wiederum zwei Lumen 6, 6' auf und ist an seiner Oberfläche mit einer in Fig. 2 schraffiert hervorgehobenen, insgesamt eine Gitterstruktur mit Axial- und Peripherstegen 8, 9 bildenden Verstärkung versehen. Dazu wird für den Innenschlauch 3 ein aushärtbares Material verwendet, das in den in Fig. 3 schraffierten Zonen bestrahlt und dadurch ausgehärtet wird. Ein Entfernen der nicht bestrahlten Zonen kann unterbleiben, so dass trotz der integrierten Verstärkung das Bauteil eine ebene Oberfläche aufweist. Um eine weitere Aushärtung des Innenschlauchs 3 und damit eine weitergehende Verstärkung durch Wachsen der Stege 8, 9 des Profilteils 5" zu verhindern, wird wiederum ein Außenschlauch 4 in der erörterten Weise aufgebracht.In the embodiment of the catheter 1 "shown in FIG. 3, the lattice structure of the profile part 5" is applied directly in the inner tube 3. In the case shown, the latter again has two lumens 6, 6 'and is provided on its surface with a hatched highlighted in Fig. 2, a total of a grid structure with axial and peripheral webs 8, 9 forming reinforcement. For this purpose, a curable material is used for the inner tube 3, which is irradiated in the hatched in Fig. 3 zones and thereby cured. A removal of the non-irradiated zones can be omitted, so that despite the integrated reinforcement, the component has a flat surface. To further harden the inner tube 3, and thus to prevent further reinforcement by growing the webs 8, 9 of the profile part 5 ", in turn, an outer tube 4 is applied in the manner discussed.

Eine weitere Ausführungsform eines Katheters 1''' ist schließlich in den Fig. 4 und 5 dargestellt. Im Innen- und Außenschlauch 3, 4 unterscheidet sich diese Ausführungsform nicht von der gemäß Fig. 1. Insoweit wird auf die dortigen Ausführungen verwiesen.Another embodiment of a catheter 1 '' 'is finally shown in Figs. 4 and 5. In the inner and outer tubes 3, 4, this embodiment does not differ from that shown in FIG. 1. In this regard, reference is made to the statements there.

Das Profilteil 5''' ist einstückig aus einem harten Kunststoff-Material, wie etwa Polycarbonat oder Polyimid, oder auch aus dünnem Metallmaterial, wie Edelstahl oder Nitinol, hergestellt und weist auf den Teillängen t1, t2 und t4 parallel mit Abstand zueinander verlaufende Peripherstege 9 auf. Diese sind als Teilringe ausgebildet, deren Enden 11 jeweils durch einen axial durchgehenden Axialsteg 8, 8' miteinander verbunden sind. Zwischen den beiden Axialstegen 8, 8' bleibt ein Spalt 12, der im Katheter 1''' als Sollbruchstelle für dessen Auftrennen zum Abnehmen von der eingeführten Elektrode dient.The profile part 5 '' 'is made in one piece from a hard plastic material, such as polycarbonate or polyimide, or from thin metal material, such as stainless steel or Nitinol, and has on the partial lengths t1, t2 and t4 parallel spaced apart peripheral webs on. These are designed as partial rings whose ends 11 are each connected to each other by an axially continuous axial web 8, 8 '. Between the two axial webs 8, 8 'remains a gap 12, which serves in the catheter 1' '' as a predetermined breaking point for its separation for removal from the inserted electrode.

Auch bei der in Fig. 4 dargestellten Ausführungsform sind die Öffnungen 7 und insbesondere Peripherstege 9 auf den verschiedenen Teillängen t1 bis t4 unterschiedlich gestaltet. In der zum distalen Ende hin angeordneten Teillänge t1 sind relativ dünne Peripherstege 9 vorgesehen, sodass dort der Katheter relativ flexibel ist. In der in proximaler Richtung sich anschließenden Teillänge t2 sind die Peripherstege 9 deutlich verbreitert, wodurch die Flexibilität abnimmt.Also in the embodiment shown in Fig. 4, the openings 7 and in particular peripheral webs 9 are designed differently on the different partial lengths t1 to t4. In the partial length t1 arranged towards the distal end, relatively thin peripheral webs 9 are provided, so that the catheter is relatively flexible there. In the partial length t2 adjoining in the proximal direction, the peripheral webs 9 are significantly widened, as a result of which the flexibility decreases.

Eine Besonderheit zeigen die Axialstege 8, 8' im Bereich der Teillänge t3. Dort weisen die Axialstege 8, 8' in Peripherrichtung P weisende Fortsätze 13, 13' auf, die so versetzt zueinander angeordnet sind, dass sie unter Bildung eines mäanderförmigen Spaltabschnittes 12' miteinander kämmen. In diesem Bereich ist der Katheter 1''' dadurch torsionsstabil.A special feature of the axial webs 8, 8 'in the region of the partial length t3. There, the axial webs 8, 8 'in the peripheral direction P facing extensions 13, 13 'which are offset relative to one another in such a way that they mesh with one another to form a meander-shaped gap section 12'. In this area, the catheter 1 '"is thus torsionally stable.

Auf der Teillänge t4 sind relativ dünne Peripherstege 9 durch in Axialrichtung breite Öffnungen 7 voneinander getrennt, sodass der Katheter dort sehr flexibel in der durch den dortigen Spalt 12 verlaufenden Mittelebene ist.On the part length t4 relatively thin peripheral webs 9 are separated from each other by axially wide openings 7, so that the catheter is there very flexible in the plane passing through the gap 12 center plane.

Es schließt sich eine Teillänge t5 an, in der keine Öffnungen außer Spalt 12 vorgesehen sind. Dadurch ist dort der Katheter 1''' sehr steif.This is followed by a partial length t5, in which no openings except gap 12 are provided. As a result, there is the catheter 1 '' 'very stiff.

In Fig. 5 ist das Profilteil 5''' auf seiner Teillänge t1 ohne Innen- und Außenschlauch dargestellt.In Fig. 5, the profile part 5 '' 'is shown on its part length t1 without inner and outer tube.

Schließlich ist zu erwähnen, dass die Profilteile aus einem Material hergestellt werden können, das für MR-Sichtgeräte kompatibel beziehungsweise in Ultraschall- oder Röntgen-Geräten detektierbar ist.Finally, it should be noted that the profile parts can be made of a material that is compatible for MR viewing devices or detectable in ultrasound or X-ray devices.

Claims (10)

Katheter, insbesondere zur Einführung von Herzschrittmacher- oder ICD-Elektroden in einen Patientenkörper, umfassend - eine Katheterwand (2), die mindestens ein Lumen (6, 6') umgrenzt, und - eine Verstärkung in Axial- und Peripherrichtung (A, P) in der Katheterwand (2) zur Stabilisierung des Katheters (1, 1', 1'', 1''') bezüglich seiner Torsions- und/oder Knicksteifigkeit, dadurch gekennzeichnet, dass - die Verstärkung als Profilteil (5, 5', 5", 5''') ausgebildet ist, das in Axial- und Peripherrichtung (A, P) des Katheters (1, 1', 1", 1''') auf dessen mechanische Solleigenschaften abgestimmt ist. Catheter, in particular for introducing pacemaker or ICD electrodes into a patient's body a catheter wall (2) delimiting at least one lumen (6, 6 '), and a reinforcement in the axial and peripheral direction (A, P) in the catheter wall (2) for stabilizing the catheter (1, 1 ', 1'',1''') with respect to its torsional and / or bending stiffness, characterized in that - The gain as a profile part (5, 5 ', 5 ", 5''') is formed in the axial and peripheral directions (A, P) of the catheter (1, 1 ', 1", 1''') on whose mechanical properties are matched. Katheter nach Anspruch 1, dadurch gekennzeichnet, dass das Profilteil (5, 5', 5", 5''') auf unterschiedlichen Teillängen (t1 bis t5) durch variable Profilierung abgestimmte Torsions-, Biege- Knicksteifigkeits-, Schlitzbarkeits- und/oder Kompressibilitätseigenschaften aufweist.Catheter according to claim 1, characterized in that the profile part (5, 5 ', 5 ", 5''') at different part lengths (t1 to t5) by means of variable profiling tuned torsion, bending buckling stiffness, Schlitzbarkeits- and / or Compressibility features. Katheter nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass das Profilteil zumindest auf einer Teillänge (t1 bis t5) als Gitterprofilteil (5, 5', 5''') mit Axial- und/oder Peripherstegen (8, 9) ausgebildet ist.Catheter according to claim 1 or 2, characterized in that the profile part at least on a partial length (t1 to t5) as a grating profile part (5, 5 ', 5''') with axial and / or peripheral webs (8, 9) is formed. Katheter nach Anspruch 3, dadurch gekennzeichnet, dass der Querschnitt der Axial- und/oder Peripherstege (8, 9) in Axial- und/oder Peripherrichtung (A, P) hinsichtlich der Torsions-, Biege-, Knicksteifigkeits-, Schlitzbarkeits- und/oder Kompressibilitätseigenschaften des Katheters (1, 1', 1''') variabel ist.Catheter according to claim 3, characterized in that the cross-section of the axial and / or peripheral webs (8, 9) in the axial and / or peripheral direction (A, P) with respect to the torsional, bending, buckling stiffness, slitability and / or or compressibility properties of the catheter (1, 1 ', 1''') is variable. Katheter nach Anspruch 3 oder 4, dadurch gekennzeichnet, dass das Gitterprofilteil (5"') teilringförmige Peripherstege (9) aufweist, die an ihren Enden durch jeweils einen axial durchgehenden Axialsteg (8, 8') verbunden sind.Catheter according to claim 3 or 4, characterized in that the grating profile part (5 "') has part-annular peripheral webs (9) which are connected at their ends by an axially continuous axial web (8, 8'). Katheter nach einem der vorgenannten Ansprüche, dadurch gekennzeichnet, dass das Profilteil (5, 5''') durch Schneiden oder Ätzen aus einem Schlauch- oder Folienteil aus Metall- oder Kunststoffmaterial hergestellt ist.Catheter according to one of the preceding claims, characterized in that the profile part (5, 5 ''') is made by cutting or etching of a tube or foil part made of metal or plastic material. Katheter nach einem der Ansprüche 1 bis 6. dadurch gekennzeichnet, dass die Stege (8, 9) des Profilteils (5") durch strahlungsinduziertes oder chemisches Vernetzen eines aushärtbaren Kunststoff-Schlauchteils oder einer aushärtbaren Beschichtung hergestellt sind.Catheter according to one of claims 1 to 6, characterized in that the webs (8, 9) of the profile part (5 ") are produced by radiation-induced or chemical crosslinking of a curable plastic tube part or a curable coating. Katheter nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass das Profilteil (5, 5', 5''') durch ein Heißverformungsverfahren, insbesondere durch Spritzgießen, Extrusion oder dergleichen hergestellt ist.Catheter according to one of claims 1 to 6, characterized in that the profile part (5, 5 ', 5''') is produced by a hot-forming process, in particular by injection molding, extrusion or the like. Katheter nach einem der vorgenannten Ansprüche, dadurch gekennzeichnet, dass das Profilteil (5, 5', 5'', 5''') in die Katheterwand (2) eingebettet, insbesondere eingespritzt ist.Catheter according to one of the preceding claims, characterized in that the profile part (5, 5 ', 5'',5''') embedded in the catheter wall (2), in particular injected. Katheter nach einem der Ansprüche 1 bis 8, dadurch gekennzeichnet, dass das Profilteil (5, 5'', 5''') zwischen einem Innenschlauch (3) und einem Außenschlauch (4) der Katheterwand (2) eingebettet ist.Catheter according to one of claims 1 to 8, characterized in that the profile part (5, 5 '', 5 ''') between an inner tube (3) and an outer tube (4) of the catheter wall (2) is embedded.
EP05022550A 2004-10-20 2005-10-15 Catheter particularly for insertion of pace-maker or ICD-electrodes into a patient's body Not-in-force EP1649889B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004051211A DE102004051211A1 (en) 2004-10-20 2004-10-20 Catheter, in particular for introducing pacemaker or ICD electrodes into a patient's body

Publications (2)

Publication Number Publication Date
EP1649889A1 true EP1649889A1 (en) 2006-04-26
EP1649889B1 EP1649889B1 (en) 2008-09-10

Family

ID=35311743

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05022550A Not-in-force EP1649889B1 (en) 2004-10-20 2005-10-15 Catheter particularly for insertion of pace-maker or ICD-electrodes into a patient's body

Country Status (4)

Country Link
US (1) US7725179B2 (en)
EP (1) EP1649889B1 (en)
AT (1) ATE407718T1 (en)
DE (2) DE102004051211A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009035745A1 (en) 2007-09-14 2009-03-19 Avalon Laboratories, Llc Cannula reinforcing band and method
EP2476455A1 (en) * 2011-01-13 2012-07-18 BIOTRONIK SE & Co. KG Implantable electrode lead
EP2789365A1 (en) * 2013-04-08 2014-10-15 Sapiens Steering Brain Stimulation B.V. A reinforcement means for a lead, especially for a lead for neural applications
US10918826B2 (en) 2007-06-26 2021-02-16 Nordson Corporation Coaxial venal cannula

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051211A1 (en) * 2004-10-20 2006-05-04 Restate Treuhand & Immobilien Ag Catheter, in particular for introducing pacemaker or ICD electrodes into a patient's body
DE102008015050A1 (en) * 2008-03-19 2009-09-24 Tracoe Medical Gmbh Tracheostomy tube made of at least two different plastics
DE102008002395A1 (en) * 2008-06-12 2009-12-17 Biotronik Vi Patent Ag Drug-loaded implant
WO2015075548A1 (en) * 2013-11-22 2015-05-28 Simon Fraser University Apparatus and methods for assisted breathing by transvascular nerve stimulation
JP2017502731A (en) * 2013-12-19 2017-01-26 スミス メディカル エーエスディー インコーポレーテッド Soft tip catheter
USD764054S1 (en) * 2014-05-29 2016-08-16 Spinal Simplicity Llc. Insertion instrument

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0608853A2 (en) * 1993-01-26 1994-08-03 Terumo Kabushiki Kaisha Vascular dilatation instrument and catheter
US5507751A (en) * 1988-11-09 1996-04-16 Cook Pacemaker Corporation Locally flexible dilator sheath
WO1996038193A1 (en) * 1995-05-31 1996-12-05 Cardia Catheter Co. Flexible tubular device for use in medical applications
EP0790066A2 (en) * 1991-02-15 1997-08-20 Ingemar H. Lundquist Steerable catheter
US5743876A (en) * 1994-03-10 1998-04-28 Schneider (Usa) Inc Catheter having shaft of varying stiffness
US6251092B1 (en) * 1997-12-30 2001-06-26 Medtronic, Inc. Deflectable guiding catheter
JP2001299923A (en) * 2000-04-25 2001-10-30 Mitsubishi Cable Ind Ltd Flexible tube and manufacturing method therefor
EP1457224A1 (en) * 2003-03-12 2004-09-15 Biosense Webster, Inc. Deflectable catheter with hinge

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1231392A (en) * 1982-10-14 1988-01-12 Edward E. Elson Flexible tip cardiac pacing catheter
US5409453A (en) * 1992-08-12 1995-04-25 Vidamed, Inc. Steerable medical probe with stylets
US5409469A (en) 1993-11-04 1995-04-25 Medtronic, Inc. Introducer system having kink resistant splittable sheath
US5713867A (en) 1996-04-29 1998-02-03 Medtronic, Inc. Introducer system having kink resistant splittable sheath
US5782811A (en) * 1996-05-30 1998-07-21 Target Therapeutics, Inc. Kink-resistant braided catheter with distal side holes
DE29702413U1 (en) * 1997-02-12 1998-06-04 Starck, Bernd, Dipl.-Ing., 75443 Ötisheim Permanent pacemaker and / or ICD electrode with a balloon to facilitate placement in the heart chamber
US6368316B1 (en) * 1998-06-11 2002-04-09 Target Therapeutics, Inc. Catheter with composite stiffener
US6159198A (en) 1998-07-16 2000-12-12 Medtronic, Inc. Introducer system
US6556873B1 (en) 1999-11-29 2003-04-29 Medtronic, Inc. Medical electrical lead having variable bending stiffness
US6549812B1 (en) * 1999-11-29 2003-04-15 Medtronic, Inc. Medical electrical lead having bending stiffness which increase in the distal direction
US6402781B1 (en) * 2000-01-31 2002-06-11 Mitralife Percutaneous mitral annuloplasty and cardiac reinforcement
US6907298B2 (en) * 2002-01-09 2005-06-14 Medtronic, Inc. Method and apparatus for imparting curves in implantable elongated medical instruments
US20040167437A1 (en) * 2003-02-26 2004-08-26 Sharrow James S. Articulating intracorporal medical device
US7993397B2 (en) * 2004-04-05 2011-08-09 Edwards Lifesciences Ag Remotely adjustable coronary sinus implant
DE102004051211A1 (en) * 2004-10-20 2006-05-04 Restate Treuhand & Immobilien Ag Catheter, in particular for introducing pacemaker or ICD electrodes into a patient's body

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5507751A (en) * 1988-11-09 1996-04-16 Cook Pacemaker Corporation Locally flexible dilator sheath
EP0790066A2 (en) * 1991-02-15 1997-08-20 Ingemar H. Lundquist Steerable catheter
EP0608853A2 (en) * 1993-01-26 1994-08-03 Terumo Kabushiki Kaisha Vascular dilatation instrument and catheter
US5743876A (en) * 1994-03-10 1998-04-28 Schneider (Usa) Inc Catheter having shaft of varying stiffness
WO1996038193A1 (en) * 1995-05-31 1996-12-05 Cardia Catheter Co. Flexible tubular device for use in medical applications
US6251092B1 (en) * 1997-12-30 2001-06-26 Medtronic, Inc. Deflectable guiding catheter
JP2001299923A (en) * 2000-04-25 2001-10-30 Mitsubishi Cable Ind Ltd Flexible tube and manufacturing method therefor
EP1457224A1 (en) * 2003-03-12 2004-09-15 Biosense Webster, Inc. Deflectable catheter with hinge

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; AN 2002-031204, XP002364398 *
PATENT ABSTRACTS OF JAPAN vol. 2002, no. 02 2 April 2002 (2002-04-02) *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10918826B2 (en) 2007-06-26 2021-02-16 Nordson Corporation Coaxial venal cannula
WO2009035745A1 (en) 2007-09-14 2009-03-19 Avalon Laboratories, Llc Cannula reinforcing band and method
EP2195051A1 (en) * 2007-09-14 2010-06-16 Avalon Laboratories, Llc Cannula reinforcing band and method
EP2195051A4 (en) * 2007-09-14 2012-03-07 Avalon Lab Llc Cannula reinforcing band and method
US8377036B2 (en) 2007-09-14 2013-02-19 Avalon Laboratories, Inc. Cannula reinforcing band and method
EP3643349A1 (en) * 2007-09-14 2020-04-29 Nordson Corporation Cannula reinforcing band
EP2476455A1 (en) * 2011-01-13 2012-07-18 BIOTRONIK SE & Co. KG Implantable electrode lead
EP2789365A1 (en) * 2013-04-08 2014-10-15 Sapiens Steering Brain Stimulation B.V. A reinforcement means for a lead, especially for a lead for neural applications
WO2014166754A1 (en) * 2013-04-08 2014-10-16 Sapiens Steering Brain Stimulation B.V. A reinforcement means for a lead, especially for a lead for neural applications
US10022533B2 (en) 2013-04-08 2018-07-17 Medtronic Bakken Research Center B.V. Reinforcement member for a medical lead

Also Published As

Publication number Publication date
EP1649889B1 (en) 2008-09-10
ATE407718T1 (en) 2008-09-15
US20060095106A1 (en) 2006-05-04
DE502005005316D1 (en) 2008-10-23
DE102004051211A1 (en) 2006-05-04
US7725179B2 (en) 2010-05-25

Similar Documents

Publication Publication Date Title
EP1649889B1 (en) Catheter particularly for insertion of pace-maker or ICD-electrodes into a patient's body
DE69525351T2 (en) SOFT, FLEXIBLE CATHETER TIP FOR USE IN ANGIOGRAPHY
DE60129843T2 (en) GUIDANCE OR DIAGNOSIS CATHETER FOR RIGHT HEART CANCER
DE69209422T2 (en) Coaxial catheter
EP0274705B1 (en) Probe for introduction into the human or animal body, in particular papillotome
EP0402885B1 (en) Flexible probe duct
DE69217710T2 (en) Marking device for endoscope accessories and manufacturing processes
EP2988049B1 (en) Method for connecting plastic tubes
EP0800800A1 (en) Stent for transluminal implantation in a hollow organ
EP1095632A2 (en) Stent having a closed cell structure
EP3423148B1 (en) Implantable cuff electrode
DE102009024602A1 (en) Angle profile for use as e.g. edge protection bracket, for reinforcement of building corner, has seam along which profile is plastically deformed, where thickness of profile in side areas of seam increases from base area to side pieces
EP1316326B1 (en) Catheter balloon
DE102015117666B4 (en) Endovascular medical device, treatment system with such a device and manufacturing method
EP1545651A1 (en) Microdialysis probe with a spiral line
DE3239032C2 (en) Catheter tube
EP3326686B1 (en) Implantable electrode lead with curved shaping part for external shaping of the electrode lead
EP1941917B2 (en) Catheter pipe element
DE3743139C2 (en) Catheters, for example for cardiac catheterization
EP3181188A1 (en) Extendable eclectrode
EP1428545A1 (en) Catheter
EP0684021A1 (en) Stent with mutually linked wires
DE3336046C2 (en)
DE10048294A1 (en) Manufacture of reinforced surgical tubing, comprises removing short section of spiral reinforcement between inner and outer layers of tube end
DE102006007967B4 (en) Method of making a reflux catheter

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK YU

17P Request for examination filed

Effective date: 20061013

17Q First examination report despatched

Effective date: 20061116

AKX Designation fees paid

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

17Q First examination report despatched

Effective date: 20061116

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REF Corresponds to:

Ref document number: 502005005316

Country of ref document: DE

Date of ref document: 20081023

Kind code of ref document: P

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20081023

Year of fee payment: 4

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

REG Reference to a national code

Ref country code: IE

Ref legal event code: FD4D

BERE Be: lapsed

Owner name: BIOTRONIK CRM PATENT A.G.

Effective date: 20081031

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20081221

Ref country code: IE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20081210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081031

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20090210

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20090110

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

26N No opposition filed

Effective date: 20090611

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081031

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20081031

Year of fee payment: 4

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081015

REG Reference to a national code

Ref country code: NL

Ref legal event code: V1

Effective date: 20100501

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100501

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081015

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20090311

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080910

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20081211

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20091015

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20121024

Year of fee payment: 8

Ref country code: GB

Payment date: 20121023

Year of fee payment: 8

REG Reference to a national code

Ref country code: SE

Ref legal event code: EUG

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20131015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20131015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20131016

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20141021

Year of fee payment: 10

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 502005005316

Country of ref document: DE

Representative=s name: RANDOLL, SOEREN, DIPL.-CHEM. UNIV. DR. RER. NA, DE

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20160630

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20151102

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20161014

Year of fee payment: 12

Ref country code: CH

Payment date: 20161025

Year of fee payment: 12

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 502005005316

Country of ref document: DE

Ref country code: DE

Ref legal event code: R081

Ref document number: 502005005316

Country of ref document: DE

Owner name: BIOTRONIK SE & CO. KG, DE

Free format text: FORMER OWNER: BIOTRONIK CRM PATENT AG, BAAR, CH

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 502005005316

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171031

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180501

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171031