EP1646367A4 - Formes dosifiees a liberation controlee a base de gomme gellane a administrer par voie orale, une nouvelle technologie pour la retention gastrique - Google Patents

Formes dosifiees a liberation controlee a base de gomme gellane a administrer par voie orale, une nouvelle technologie pour la retention gastrique

Info

Publication number
EP1646367A4
EP1646367A4 EP04744994A EP04744994A EP1646367A4 EP 1646367 A4 EP1646367 A4 EP 1646367A4 EP 04744994 A EP04744994 A EP 04744994A EP 04744994 A EP04744994 A EP 04744994A EP 1646367 A4 EP1646367 A4 EP 1646367A4
Authority
EP
European Patent Office
Prior art keywords
dosage forms
controlled release
release dosage
gellan gum
gastric retention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04744994A
Other languages
German (de)
English (en)
Other versions
EP1646367A2 (fr
Inventor
David Hoikhman
Yoram Sela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NESHER SOLUTIONS LTD.
Original Assignee
NESHER SOLUTIONS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NESHER SOLUTIONS Ltd filed Critical NESHER SOLUTIONS Ltd
Publication of EP1646367A2 publication Critical patent/EP1646367A2/fr
Publication of EP1646367A4 publication Critical patent/EP1646367A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
EP04744994A 2003-07-21 2004-07-19 Formes dosifiees a liberation controlee a base de gomme gellane a administrer par voie orale, une nouvelle technologie pour la retention gastrique Withdrawn EP1646367A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48842103P 2003-07-21 2003-07-21
PCT/IL2004/000654 WO2005007074A2 (fr) 2003-07-21 2004-07-19 Formes dosifiees a liberation controlee a base de gomme gellane a administrer par voie orale, une nouvelle technologie pour la retention gastrique

Publications (2)

Publication Number Publication Date
EP1646367A2 EP1646367A2 (fr) 2006-04-19
EP1646367A4 true EP1646367A4 (fr) 2011-06-15

Family

ID=34079422

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04744994A Withdrawn EP1646367A4 (fr) 2003-07-21 2004-07-19 Formes dosifiees a liberation controlee a base de gomme gellane a administrer par voie orale, une nouvelle technologie pour la retention gastrique

Country Status (4)

Country Link
US (1) US20060177497A1 (fr)
EP (1) EP1646367A4 (fr)
CA (1) CA2533165A1 (fr)
WO (1) WO2005007074A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1067910B1 (fr) 1998-04-03 2004-05-26 Egalet A/S Composition a liberation controllee
WO2003024429A1 (fr) 2001-09-21 2003-03-27 Egalet A/S Systeme de liberation a base de polymere
US20040253310A1 (en) 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
AU2003275953A1 (en) 2002-11-08 2004-06-07 Egalet A/S Controlled release carvedilol compositions
EP1610767B1 (fr) 2003-03-26 2011-01-19 Egalet A/S Systeme de liberation regulee de morphine
EP2186510B1 (fr) 2003-03-26 2013-07-10 Egalet Ltd. Compositions matricielles pour l'administration contrôlée de médicaments
EP2258349B1 (fr) 2004-05-11 2014-07-16 Egalet Ltd. Forme pharmaceutique gonflable comportant de la gomme de gellane
AU2008258596B2 (en) 2007-06-04 2013-02-14 Egalet Ltd Controlled release pharmaceutical compositions for prolonged effect
US10463623B2 (en) * 2008-09-22 2019-11-05 Rubicon Research Private Limited Compositions exhibiting delayed transit through the gastrointestinal tract
EP2393484A1 (fr) 2009-02-06 2011-12-14 Egalet Ltd. Composition à libération immédiate résistant à une maltraitance par prise d'alcool
CA2766179A1 (fr) 2009-06-24 2010-12-29 Egalet Ltd. Formulations a liberation controlee
WO2011125075A2 (fr) * 2010-04-08 2011-10-13 Fdc Limited Nouveau système d'administration à rétention gastrique de macrolides
EP2877161A1 (fr) 2012-07-06 2015-06-03 Egalet Ltd. Compositions pharmaceutiques de dissuasion d'abus à libération contrôlée
WO2016130908A1 (fr) 2015-02-13 2016-08-18 The University Of Toledo Polysaccharide thérapeutique midi-gagr et matériaux et procédés apparentés
MX2018011278A (es) 2016-03-17 2019-07-08 Thiogenesis Therapeutics Inc Composiciones para la liberacion controlada de cisteamina y el tratamiento sistemico de trastornos sensibles a la cisteamina.
JP7208982B2 (ja) 2017-09-20 2023-01-19 チオジェネシス セラピューティクス, インコーポレイテッド システアミン感受性障害の治療方法
US11389398B2 (en) 2019-05-14 2022-07-19 Clexio Biosciences Ltd. Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
WO2022195476A1 (fr) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Dispositifs de rétention gastrique pour l'évaluation d'états intragastriques

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10236983A (ja) * 1997-02-25 1998-09-08 Taisho Pharmaceut Co Ltd ゲル状徐放性組成物
WO1999022768A1 (fr) * 1997-10-31 1999-05-14 Monsanto Company Composition a liberation lente comprenant des gels a gomme gellane
WO2000033818A1 (fr) * 1998-12-11 2000-06-15 Nostrum Pharmaceuticals, Inc. Comprime a liberation prolongee contenant un hydrocolloide et un ether de cellulose
WO2002017885A2 (fr) * 2000-08-29 2002-03-07 Ranbaxy Laboratories Limited Formulation a liberation controlee d'erythromycine ou de derive de cette substance
US20030129230A1 (en) * 2001-07-06 2003-07-10 Penwest Pharmaceuticals Company Sustained release formulations of oxymorphone

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
CA2125914A1 (fr) * 1993-06-25 1994-12-26 Pharmacia Corporation Gomme gellan sous forme de microparticules revetues d'huile
US5662933A (en) * 1993-09-09 1997-09-02 Edward Mendell Co., Inc. Controlled release formulation (albuterol)
EP0971641A4 (fr) * 1997-04-03 2003-08-13 Point Biomedical Corp Systeme intravesical de liberation de medicaments
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
EP1004310B1 (fr) * 1997-06-20 2009-06-17 Ohkura Pharmaceutical Co., Ltd. Composition sous forme de gel
DE69828289T2 (de) * 1997-08-11 2005-06-02 Alza Corp., Mountain View Dosierungsform für verzögerte Freisetzung eines Wirkstoffs
TW408153B (en) * 1998-01-09 2000-10-11 Asahi Chemical Ind Cellulose-containing composite, process for its preparation and use thereof
US6500459B1 (en) * 1999-07-21 2002-12-31 Harinderpal Chhabra Controlled onset and sustained release dosage forms and the preparation thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10236983A (ja) * 1997-02-25 1998-09-08 Taisho Pharmaceut Co Ltd ゲル状徐放性組成物
WO1999022768A1 (fr) * 1997-10-31 1999-05-14 Monsanto Company Composition a liberation lente comprenant des gels a gomme gellane
WO2000033818A1 (fr) * 1998-12-11 2000-06-15 Nostrum Pharmaceuticals, Inc. Comprime a liberation prolongee contenant un hydrocolloide et un ether de cellulose
WO2002017885A2 (fr) * 2000-08-29 2002-03-07 Ranbaxy Laboratories Limited Formulation a liberation controlee d'erythromycine ou de derive de cette substance
US20030129230A1 (en) * 2001-07-06 2003-07-10 Penwest Pharmaceuticals Company Sustained release formulations of oxymorphone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"GELLAN GUM WINS IFT'S FOOD TECHNOLOGY INDUSTRIAL ACHIEVEMENT AWARD", FOOD TECHNOLOGY, INSTITUTE OF FOOD TECHNOLOGISTS, CHICAGO, IL, US, vol. 47, no. 9, 1 September 1993 (1993-09-01), pages 94 - 96, XP000400605, ISSN: 0015-6639 *
DATABASE WPI Week 199846, Derwent World Patents Index; AN 1998-537401, XP002634366 *

Also Published As

Publication number Publication date
WO2005007074A2 (fr) 2005-01-27
US20060177497A1 (en) 2006-08-10
WO2005007074A3 (fr) 2005-07-07
EP1646367A2 (fr) 2006-04-19
CA2533165A1 (fr) 2005-01-27

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20060116

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NESHER SOLUTIONS LTD.

A4 Supplementary search report drawn up and despatched

Effective date: 20110516

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110817