EP1632286A4 - Separating agent for optical isomer - Google Patents

Separating agent for optical isomer

Info

Publication number
EP1632286A4
EP1632286A4 EP04728898A EP04728898A EP1632286A4 EP 1632286 A4 EP1632286 A4 EP 1632286A4 EP 04728898 A EP04728898 A EP 04728898A EP 04728898 A EP04728898 A EP 04728898A EP 1632286 A4 EP1632286 A4 EP 1632286A4
Authority
EP
European Patent Office
Prior art keywords
separating agent
derivative
optical isomer
provides
porous carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP04728898A
Other languages
German (de)
French (fr)
Other versions
EP1632286B1 (en
EP1632286A1 (en
Inventor
Yoshio Okamoto
Chiyo Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daicel Corp
Original Assignee
Daicel Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chemical Industries Ltd filed Critical Daicel Chemical Industries Ltd
Publication of EP1632286A1 publication Critical patent/EP1632286A1/en
Publication of EP1632286A4 publication Critical patent/EP1632286A4/en
Application granted granted Critical
Publication of EP1632286B1 publication Critical patent/EP1632286B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3833—Chiral chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)

Abstract

The present invention provides a separating agent for enantiomeric isomers which exhibits high optical resolving power together with solvent resistance. That is, the present invention provides a separating agent for enantiomeric isomers including a polysaccharide derivative such as a carbamate derivative or ester derivative of cellulose or amylose carried on a porous carrier such as silica gel, in which the porous carrier having an epoxy group and part of hydroxyl groups of the polysaccharide derivative are chemically bonded.
EP04728898A 2003-04-24 2004-04-22 Separating agent for optical isomer Expired - Lifetime EP1632286B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003119326 2003-04-24
PCT/JP2004/005757 WO2004095018A1 (en) 2003-04-24 2004-04-22 Separating agent for optical isomer

Publications (3)

Publication Number Publication Date
EP1632286A1 EP1632286A1 (en) 2006-03-08
EP1632286A4 true EP1632286A4 (en) 2007-09-12
EP1632286B1 EP1632286B1 (en) 2011-04-20

Family

ID=33308098

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04728898A Expired - Lifetime EP1632286B1 (en) 2003-04-24 2004-04-22 Separating agent for optical isomer

Country Status (8)

Country Link
US (1) US7772153B2 (en)
EP (1) EP1632286B1 (en)
JP (1) JP4294028B2 (en)
KR (1) KR101011784B1 (en)
CN (1) CN100391593C (en)
AT (1) ATE506118T1 (en)
DE (1) DE602004032335D1 (en)
WO (1) WO2004095018A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006150214A (en) * 2004-11-29 2006-06-15 Daicel Chem Ind Ltd Separating agent for optical isomer, and separation column for optical isomer
WO2007129659A1 (en) * 2006-05-09 2007-11-15 National University Corporation Nagoya University Filler for optical isomer separation
EP2028487B1 (en) 2006-05-09 2014-01-01 National University Corporation Nagoya University Filler for optical isomer separation
WO2007148834A1 (en) 2006-06-23 2007-12-27 Daicel Chemical Industries, Ltd Method of analyzing optical isomers or method of resolving the same
EP2472255B1 (en) * 2009-08-26 2016-05-25 Daicel Corporation Separating agent for optical isomer
US8859757B2 (en) * 2010-06-18 2014-10-14 Daicel Corporation Separating agent for optical isomers
CN102060995B (en) * 2010-11-19 2012-06-06 中南大学 Method for preparing silica gel supported dithiocarbamate heavy metal chelating resin
EP2522647B1 (en) 2011-05-10 2014-04-30 DSM IP Assets B.V. Process of separating chiral isomers of chroman compounds and their derivatives and precursors
EP2573063A1 (en) 2011-09-23 2013-03-27 DSM IP Assets B.V. Process for preparing chiral quinone
CN104028253B (en) * 2014-06-23 2015-10-28 镇江出入境检验检疫局检验检疫综合技术中心 A kind of gold nano grain-polysaccharide bonded silica gel stationary phase and preparation method thereof
CN106268657A (en) * 2015-05-14 2017-01-04 株式会社大赛璐 Agent for separating optical isomers
WO2023208514A1 (en) 2022-04-28 2023-11-02 F. Hoffmann-La Roche Ag Chiral separation of n-phthaloyl-d/l-glutamic acid

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539399A (en) * 1984-07-27 1985-09-03 Advanced Separation Technologies Inc. Bonded phase material for chromatographic separations
US5030354A (en) * 1986-04-02 1991-07-09 Eisai Co., Ltd. Separation agent for optical isomers
US5089642A (en) * 1985-12-27 1992-02-18 Daicel Chemical Industries, Ltd. Optically active carboalkylated amino alcohols and their utilization in optical resolution
JPH06329561A (en) * 1993-05-24 1994-11-29 Daicel Chem Ind Ltd Separating agent
EP1500430A2 (en) * 2003-05-30 2005-01-26 Daicel Chemical Industries, Ltd. Separating agent for optical isomers, method of production thereof, and separation column for optical isomers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0730122B2 (en) 1986-05-19 1995-04-05 ダイセル化学工業株式会社 Method for producing polysaccharide derivative
US5302633A (en) * 1990-11-29 1994-04-12 Nacalai Tesque, Inc. Optical resolution agent and process for the preparation of the same
JP2535446B2 (en) 1990-11-29 1996-09-18 ナカライテスク株式会社 Method for producing optical resolving agent
JP3190206B2 (en) * 1993-06-22 2001-07-23 ダイセル化学工業株式会社 Separating agent for optical isomers and method for producing the same
US5679572A (en) * 1993-09-22 1997-10-21 Daicel Chemical Industries, Ltd. Separation of chiral compounds on polysaccharide supports
JP2751004B2 (en) 1993-09-22 1998-05-18 ダイセル化学工業株式会社 Novel polysaccharide derivative, its production method and its use
CN1136183C (en) * 1994-02-25 2004-01-28 代科化学工业株式会社 Process for producing optically active mevalonolactone compound
JP3478595B2 (en) * 1994-05-17 2003-12-15 ダイセル化学工業株式会社 Separating agent for optical isomers
JPH11255671A (en) * 1998-03-11 1999-09-21 Daicel Chem Ind Ltd Chromatographic separation of optical isomer
JP2002350413A (en) * 2001-05-24 2002-12-04 Daicel Chem Ind Ltd Separation column
US6736967B2 (en) * 2001-06-07 2004-05-18 Daicel Chemical Industries, Ltd. Separating agent for enantiomeric isomers

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539399A (en) * 1984-07-27 1985-09-03 Advanced Separation Technologies Inc. Bonded phase material for chromatographic separations
US5089642A (en) * 1985-12-27 1992-02-18 Daicel Chemical Industries, Ltd. Optically active carboalkylated amino alcohols and their utilization in optical resolution
US5030354A (en) * 1986-04-02 1991-07-09 Eisai Co., Ltd. Separation agent for optical isomers
JPH06329561A (en) * 1993-05-24 1994-11-29 Daicel Chem Ind Ltd Separating agent
EP1500430A2 (en) * 2003-05-30 2005-01-26 Daicel Chemical Industries, Ltd. Separating agent for optical isomers, method of production thereof, and separation column for optical isomers

Also Published As

Publication number Publication date
KR20070066815A (en) 2007-06-27
CN100391593C (en) 2008-06-04
US7772153B2 (en) 2010-08-10
ATE506118T1 (en) 2011-05-15
DE602004032335D1 (en) 2011-06-01
CN1758959A (en) 2006-04-12
JP4294028B2 (en) 2009-07-08
EP1632286B1 (en) 2011-04-20
KR101011784B1 (en) 2011-02-07
US20060189796A1 (en) 2006-08-24
JPWO2004095018A1 (en) 2006-07-13
EP1632286A1 (en) 2006-03-08
WO2004095018A1 (en) 2004-11-04

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