EP1615492A4 - Verfahren zur korrektur von mitose-spindeldefekten beim somatischen zellkerntransfer bei tieren - Google Patents

Verfahren zur korrektur von mitose-spindeldefekten beim somatischen zellkerntransfer bei tieren

Info

Publication number
EP1615492A4
EP1615492A4 EP04759332A EP04759332A EP1615492A4 EP 1615492 A4 EP1615492 A4 EP 1615492A4 EP 04759332 A EP04759332 A EP 04759332A EP 04759332 A EP04759332 A EP 04759332A EP 1615492 A4 EP1615492 A4 EP 1615492A4
Authority
EP
European Patent Office
Prior art keywords
animals
methods
somatic cell
nuclear transfer
cell nuclear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04759332A
Other languages
English (en)
French (fr)
Other versions
EP1615492A2 (de
Inventor
Gerald Schatten
Calvin Simerly
Christopher Navara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAGEE-WOMENS HEALTH Corp
MAGEE WOMENS HEALTH CORP
Original Assignee
MAGEE-WOMENS HEALTH Corp
MAGEE WOMENS HEALTH CORP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAGEE-WOMENS HEALTH Corp, MAGEE WOMENS HEALTH CORP filed Critical MAGEE-WOMENS HEALTH Corp
Publication of EP1615492A2 publication Critical patent/EP1615492A2/de
Publication of EP1615492A4 publication Critical patent/EP1615492A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877Techniques for producing new mammalian cloned embryos
    • C12N15/8776Primate embryos
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/106Primate
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP04759332A 2003-04-09 2004-04-09 Verfahren zur korrektur von mitose-spindeldefekten beim somatischen zellkerntransfer bei tieren Withdrawn EP1615492A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46113903P 2003-04-09 2003-04-09
PCT/US2004/010977 WO2004091288A2 (en) 2003-04-09 2004-04-09 Correcting mitotic spindle defects in somatic cell nuclear transfer

Publications (2)

Publication Number Publication Date
EP1615492A2 EP1615492A2 (de) 2006-01-18
EP1615492A4 true EP1615492A4 (de) 2010-07-14

Family

ID=33299770

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04759332A Withdrawn EP1615492A4 (de) 2003-04-09 2004-04-09 Verfahren zur korrektur von mitose-spindeldefekten beim somatischen zellkerntransfer bei tieren

Country Status (5)

Country Link
US (3) US20040268422A1 (de)
EP (1) EP1615492A4 (de)
JP (1) JP2006522609A (de)
KR (1) KR20060057528A (de)
WO (1) WO2004091288A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040229350A1 (en) * 2003-05-12 2004-11-18 Nikolai Strelchenko Morula derived embryonic stem cells
US7683236B2 (en) * 2003-06-10 2010-03-23 Trustees Of The University Of Pennsylvania Enhanced production of cloned mammals by zona pellucida-free homologous mammalian embryo aggregation
CN103356708B (zh) 2005-03-31 2016-01-20 斯丹姆涅恩有限公司 制备用以预防手术后疝形成的药物的方法
KR102473092B1 (ko) 2014-09-15 2022-12-01 칠드런'즈 메디컬 센터 코포레이션 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물
CN111369869A (zh) * 2020-04-24 2020-07-03 安庆市第一中学 一种生物教学用动态减数分裂模型及其使用方法
EP4155386A1 (de) 2021-09-27 2023-03-29 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Stabilisierung der menschlichen spindel durch kifc1/hset

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030046722A1 (en) * 2000-12-22 2003-03-06 Philippe Collas Methods for cloning mammals using reprogrammed donor chromatin or donor cells

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874301A (en) * 1994-11-21 1999-02-23 National Jewish Center For Immunology And Respiratory Medicine Embryonic cell populations and methods to isolate such populations
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5905042A (en) 1996-04-01 1999-05-18 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from bovine or porcine embryos
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
US6011197A (en) * 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
EP1141265B1 (de) * 1999-01-13 2008-09-03 Revivicor, Inc. Doppelkerntransfersverfahren und dessen ergebnisse
US20010044937A1 (en) * 1999-12-17 2001-11-22 Gerald Schatten Methods for producing transgenic animals
EP1248517A2 (de) * 2000-01-07 2002-10-16 Oregon Health and Science University Klonale fortpflanzung von primaten durch embryonenspaltung
AU2002324790A1 (en) * 2001-08-24 2003-03-10 Incyte Genomics, Inc. Transmembrane protein differentially expressed in cancer
JP2004248505A (ja) * 2001-09-21 2004-09-09 Norio Nakatsuji 移植抗原の一部または全てを欠除したes細胞由来の未分化な体細胞融合細胞およびその製造
US20060037086A1 (en) * 2003-04-09 2006-02-16 Schatten Gerald P Methods for correcting mitotic spindle defects and optimizing preimplantation embryonic developmental rates associated with somatic cell nuclear transfer in animals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030046722A1 (en) * 2000-12-22 2003-03-06 Philippe Collas Methods for cloning mammals using reprogrammed donor chromatin or donor cells

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 2000, SUTOVSKY P ET AL: "Paternal contributions to the mammalian zygote: fertilization after sperm-egg fusion.", XP002584420, Database accession no. NLM10603574 *
HEWITSON LAURA ET AL: "Rhesus offspring produced by intracytoplasmic injection of testicular sperm and elongated spermatids", FERTILITY AND STERILITY, vol. 77, no. 4, April 2002 (2002-04-01), pages 794 - 801, XP002584417, ISSN: 0015-0282 *
LANZA R ET AL: "Comment on "Molecular correlates of primate nuclear transfer failures"", SCIENCE (NEW YORK, N.Y.) 12 SEP 2003 LNKD- PUBMED:12970549, vol. 301, no. 5639, 12 September 2003 (2003-09-12), pages 1482B, XP002584418, ISSN: 1095-9203 *
MOREIRA P N ET AL: "ARCHITEXTURAL DEFECTS IN PRONUCLEI OF MOUSE NUCLEAR TRANSPLANT EMBRYOS", JOURNAL OF CELL SCIENCE, CAMBRIDGE UNIVERSITY PRESS, LONDON, GB LNKD- DOI:10.1242/JCS.00692, vol. 116, no. 18, 15 September 2003 (2003-09-15), pages 3713 - 3720, XP009024143, ISSN: 0021-9533 *
NG S-C ET AL: "The First Cell Cycle After Transfer of Somatic Cell Nuclei In a Non-Human Primate", DEVELOPMENT, COMPANY OF BIOLOGISTS, CAMBRIDGE, GB LNKD- DOI:10.1242/DEV.01118, vol. 131, no. 10, 1 January 2004 (2004-01-01), pages 2475 - 2484, XP003014092, ISSN: 0950-1991 *
SCHATTEN G ET AL: "Response to Comment on "Molecular correlates of primate nuclear transfer failures"", SCIENCE (NEW YORK, N.Y.) 12 SEP 2003 LNKD- PUBMED:12970549, vol. 301, no. 5639, 12 September 2003 (2003-09-12), pages 1482C, XP002584419, ISSN: 1095-9203 *
See also references of WO2004091288A2 *
SIMERLY CALVIN ET AL: "Molecular correlates of primate nuclear transfer failures", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US LNKD- DOI:10.1126/SCIENCE.1082091, vol. 300, no. 5617, 11 April 2003 (2003-04-11), pages 297, XP002479062, ISSN: 0036-8075 *
VOGEL G: "Nuclear Transfer. Misguided chromosomes foil primate cloning", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US LNKD- DOI:10.1126/SCIENCE.300.5617.225, vol. 300, no. 5617, 11 April 2003 (2003-04-11), pages 225 - 227, XP002985809, ISSN: 0036-8075 *
WOLF D P ET AL: "NUCLEAR TRANSFER IN THE RHESUS MONKEY: PRACTICAL AND BASIC IMPLICATIONS", BIOLOGY OF REPRODUCTION, SOCIETY FOR THE STUDY OF REPRODUCTION, CHAMPAIGN, IL, US LNKD- DOI:10.1095/BIOLREPROD60.2.199, vol. 60, 1 January 1999 (1999-01-01), pages 199 - 204, XP002946450, ISSN: 0006-3363 *

Also Published As

Publication number Publication date
WO2004091288A2 (en) 2004-10-28
KR20060057528A (ko) 2006-05-26
JP2006522609A (ja) 2006-10-05
US20100242125A1 (en) 2010-09-23
EP1615492A2 (de) 2006-01-18
US20080263692A1 (en) 2008-10-23
US20040268422A1 (en) 2004-12-30
WO2004091288A3 (en) 2004-12-29

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