EP1581350A4 - Method and apparatus for sorting particles - Google Patents

Method and apparatus for sorting particles

Info

Publication number
EP1581350A4
EP1581350A4 EP03752432A EP03752432A EP1581350A4 EP 1581350 A4 EP1581350 A4 EP 1581350A4 EP 03752432 A EP03752432 A EP 03752432A EP 03752432 A EP03752432 A EP 03752432A EP 1581350 A4 EP1581350 A4 EP 1581350A4
Authority
EP
European Patent Office
Prior art keywords
sorting particles
sorting
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03752432A
Other languages
German (de)
French (fr)
Other versions
EP1581350A2 (en
Inventor
John R Gilbert
Sebastian Boehm
Manish Deshpande
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytonome ST LLC
Original Assignee
Cytonome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/329,008 external-priority patent/US6976590B2/en
Application filed by Cytonome Inc filed Critical Cytonome Inc
Publication of EP1581350A2 publication Critical patent/EP1581350A2/en
Publication of EP1581350A4 publication Critical patent/EP1581350A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03BSEPARATING SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS
    • B03B5/00Washing granular, powdered or lumpy materials; Wet separating
    • B03B5/02Washing granular, powdered or lumpy materials; Wet separating using shaken, pulsated or stirred beds as the principal means of separation
    • B03B5/10Washing granular, powdered or lumpy materials; Wet separating using shaken, pulsated or stirred beds as the principal means of separation on jigs
    • B03B5/22Washing granular, powdered or lumpy materials; Wet separating using shaken, pulsated or stirred beds as the principal means of separation on jigs using pulses generated by liquid injection
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B07SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07CPOSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34Sorting according to other particular properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477Multiparameters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497Particle shape

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
EP03752432A 2002-09-16 2003-09-16 Method and apparatus for sorting particles Withdrawn EP1581350A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US41105802P 2002-09-16 2002-09-16
US41114302P 2002-09-16 2002-09-16
US411143P 2002-09-16
US411058P 2002-09-16
US329008 2002-12-23
US10/329,008 US6976590B2 (en) 2002-06-24 2002-12-23 Method and apparatus for sorting particles
PCT/US2003/029198 WO2004025266A2 (en) 2002-09-16 2003-09-16 Method and apparatus for sorting particles

Publications (2)

Publication Number Publication Date
EP1581350A2 EP1581350A2 (en) 2005-10-05
EP1581350A4 true EP1581350A4 (en) 2009-09-23

Family

ID=31999089

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03752432A Withdrawn EP1581350A4 (en) 2002-09-16 2003-09-16 Method and apparatus for sorting particles

Country Status (7)

Country Link
EP (1) EP1581350A4 (en)
JP (1) JP2005538727A (en)
KR (1) KR100990016B1 (en)
AU (1) AU2003270722A1 (en)
BR (1) BR0314268A (en)
CA (1) CA2499245A1 (en)
WO (1) WO2004025266A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4047336B2 (en) * 2005-02-08 2008-02-13 独立行政法人科学技術振興機構 Cell sorter chip with gel electrode
JP4509166B2 (en) 2007-11-02 2010-07-21 ソニー株式会社 Method and apparatus for measuring fine particles
KR100940099B1 (en) * 2008-04-02 2010-02-02 한국기계연구원 Device and Method for Discriminating between Cancerous and Normal Cells
JP4661942B2 (en) 2008-05-13 2011-03-30 ソニー株式会社 Microchip and its channel structure
JP2010226978A (en) * 2009-03-26 2010-10-14 Mitsui Eng & Shipbuild Co Ltd Cell sorter
ES2638861T3 (en) 2009-04-13 2017-10-24 University Of Washington Rare particle detection method and apparatus
EP2462245B1 (en) 2009-08-06 2016-10-05 Cornell University Device and methods for epigenetic analysis
KR101252829B1 (en) * 2009-10-06 2013-04-11 한국전자통신연구원 Array apparatus for separation of single cell
US9815060B2 (en) 2010-11-18 2017-11-14 The Regents Of The University Of California Method and device for high-throughput solution exchange for cell and particle suspensions
WO2012067985A2 (en) 2010-11-18 2012-05-24 The Regents Of The University Of California Method and device for high-throughput solution exchange for cell and particle suspensions
JP5720233B2 (en) 2010-12-17 2015-05-20 ソニー株式会社 Microchip and fine particle sorting device
EP2602608B1 (en) * 2011-12-07 2016-09-14 Imec Analysis and sorting of biological cells in flow
US9952126B2 (en) 2012-02-29 2018-04-24 Fluidigm Corporation Methods for multiple single-cell capturing and processing using micro fluidics
JP2015519900A (en) * 2012-05-21 2015-07-16 フリューダイム・コーポレイション Single particle analysis method and single particle isolation method for particle population
WO2014013802A1 (en) 2012-07-18 2014-01-23 ソニー株式会社 Microparticle isolation device, microchip for microparticle isolation, and microparticle isolation method
JP6036496B2 (en) 2012-07-24 2016-11-30 ソニー株式会社 Fine particle sorting method
JP5910412B2 (en) 2012-08-16 2016-04-27 ソニー株式会社 Microparticle sorting method and microchip for sorting microparticles
SG10201707485YA (en) * 2013-03-15 2017-10-30 Fluidigm Corp Methods and devices for analysis of defined multicellular combinations
EP3017308A4 (en) 2013-07-05 2017-04-26 University Of Washington Through Its Center For Commercialization Methods, compositions and systems for microfluidic assays
CA2995670A1 (en) 2014-08-14 2016-02-18 The Trustees Of The University Of Pennsylvania Apparatus and methods for analyzing the output of microfluidic devices
WO2016175864A1 (en) * 2015-04-30 2016-11-03 Hewlett-Packard Development Company, L.P. Target constituent location and discharge
CN113866076A (en) * 2016-05-17 2021-12-31 索尼公司 Particle extraction device and particle extraction method
CN108251291A (en) * 2016-12-29 2018-07-06 上海新微技术研发中心有限公司 Cell screening device and cell screening method
WO2019025613A1 (en) * 2017-08-04 2019-02-07 Sbt Instruments Aps Microfluidic particle analysis device
RU2020111806A (en) * 2017-08-22 2021-09-23 Елеген Корпорейшн MICROFLUID POSITION TRACKING AND ENCODING DEVICES
JP2020041881A (en) * 2018-09-10 2020-03-19 ソニー株式会社 Control device, device and system for fractionating fine particle using control device, control method, and control program
WO2021257068A1 (en) * 2020-06-17 2021-12-23 Hewlett-Packard Development Company, L.P. Determining an error in detected passage of a target particle population

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998052691A1 (en) * 1997-05-16 1998-11-26 Alberta Research Council Microfluidic system and methods of use
US5932100A (en) * 1995-06-16 1999-08-03 University Of Washington Microfabricated differential extraction device and method
US20020058332A1 (en) * 2000-09-15 2002-05-16 California Institute Of Technology Microfabricated crossflow devices and methods

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE48477T1 (en) * 1984-09-11 1989-12-15 Partec Ag METHOD AND DEVICE FOR SORTING MICROSCOPIC PARTICLES.
JPS63259466A (en) * 1987-04-16 1988-10-26 Hitachi Ltd Cell analyzer
JPH01170853A (en) * 1987-12-25 1989-07-05 Hitachi Ltd Cell screening device
CA1328861C (en) * 1988-09-30 1994-04-26 Occam Marine Technologies Ltd. Low speed particle concentrator
HU203288B (en) * 1989-04-01 1991-07-29 Mta Mueszaki Kemiai Kutato Int Apparatus for carrying out biocatalytic processes by means of biocatalyzer of solid phase
US5204884A (en) * 1991-03-18 1993-04-20 University Of Rochester System for high-speed measurement and sorting of particles
JP3226012B2 (en) * 1995-11-17 2001-11-05 矢崎総業株式会社 Equipment for separating microscopic substances in culture solution
EP0925494B1 (en) * 1996-09-04 2001-12-19 Scandinavian Micro Biodevices A/S A micro flow system for particle separation and analysis
US6221654B1 (en) * 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
IT1295939B1 (en) * 1997-10-31 1999-05-28 Giammaria Sitar DEVICE AND METHOD FOR THE SEPARATION OF HUMAN OR ANIMAL CELLS WITH DIFFERENT DENSITIES FROM CELL DISPERSIONS THAT CONTAIN THEM
US6592821B1 (en) * 1999-05-17 2003-07-15 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932100A (en) * 1995-06-16 1999-08-03 University Of Washington Microfabricated differential extraction device and method
WO1998052691A1 (en) * 1997-05-16 1998-11-26 Alberta Research Council Microfluidic system and methods of use
US20020058332A1 (en) * 2000-09-15 2002-05-16 California Institute Of Technology Microfabricated crossflow devices and methods

Also Published As

Publication number Publication date
EP1581350A2 (en) 2005-10-05
KR100990016B1 (en) 2010-10-26
JP2005538727A (en) 2005-12-22
BR0314268A (en) 2005-07-26
AU2003270722A1 (en) 2004-04-30
WO2004025266A2 (en) 2004-03-25
WO2004025266A3 (en) 2005-08-04
KR20050047540A (en) 2005-05-20
CA2499245A1 (en) 2004-03-25

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Effective date: 20090821

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