EP1579214A4 - Methods of screening for anti-inflammatory drugs and use thereof - Google Patents

Methods of screening for anti-inflammatory drugs and use thereof

Info

Publication number
EP1579214A4
EP1579214A4 EP03780600A EP03780600A EP1579214A4 EP 1579214 A4 EP1579214 A4 EP 1579214A4 EP 03780600 A EP03780600 A EP 03780600A EP 03780600 A EP03780600 A EP 03780600A EP 1579214 A4 EP1579214 A4 EP 1579214A4
Authority
EP
European Patent Office
Prior art keywords
screening
methods
inflammatory drugs
inflammatory
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03780600A
Other languages
German (de)
French (fr)
Other versions
EP1579214A2 (en
Inventor
Paul Gregor
Nicholas Harris
Juraj Koppel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rimonyx Pharmaceuticals Ltd
Original Assignee
Rimonyx Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rimonyx Pharmaceuticals Ltd filed Critical Rimonyx Pharmaceuticals Ltd
Publication of EP1579214A2 publication Critical patent/EP1579214A2/en
Publication of EP1579214A4 publication Critical patent/EP1579214A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP03780600A 2002-12-31 2003-12-30 Methods of screening for anti-inflammatory drugs and use thereof Withdrawn EP1579214A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL15376202A IL153762A0 (en) 2002-12-31 2002-12-31 Methods of screening for anti-inflammatory drugs and use thereof
IL15376202 2002-12-31
PCT/IL2003/001116 WO2004059278A2 (en) 2002-12-31 2003-12-30 Methods of screening for anti-inflammatory drugs and use thereof

Publications (2)

Publication Number Publication Date
EP1579214A2 EP1579214A2 (en) 2005-09-28
EP1579214A4 true EP1579214A4 (en) 2008-08-27

Family

ID=29798407

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03780600A Withdrawn EP1579214A4 (en) 2002-12-31 2003-12-30 Methods of screening for anti-inflammatory drugs and use thereof

Country Status (4)

Country Link
EP (1) EP1579214A4 (en)
AU (1) AU2003288698A1 (en)
IL (1) IL153762A0 (en)
WO (1) WO2004059278A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005396A1 (en) * 1991-09-12 1993-03-18 Novo Nordisk A/S A method of screening for inhibitors of heparin-binding protein
WO2003013590A1 (en) * 2001-08-09 2003-02-20 Novartis Forschungsstiftung Use of heparin-binding domain of fibronectin for diagnosis and treatment of cancer
WO2004070386A2 (en) * 2003-02-05 2004-08-19 The Nottingham Trent University Novel screening method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1156816A4 (en) * 1999-02-02 2004-12-29 Univ Jefferson Peptides modulating activities of heparin, other glycosaminoglycans or proteoglycans

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005396A1 (en) * 1991-09-12 1993-03-18 Novo Nordisk A/S A method of screening for inhibitors of heparin-binding protein
WO2003013590A1 (en) * 2001-08-09 2003-02-20 Novartis Forschungsstiftung Use of heparin-binding domain of fibronectin for diagnosis and treatment of cancer
WO2004070386A2 (en) * 2003-02-05 2004-08-19 The Nottingham Trent University Novel screening method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VARKI A: "Selectin ligands", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 2:91, no. 16, 1 August 1994 (1994-08-01), pages 7390 - 7397, XP002135379, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2004059278A2 (en) 2004-07-15
IL153762A0 (en) 2003-07-06
AU2003288698A1 (en) 2004-07-22
AU2003288698A8 (en) 2004-07-22
EP1579214A2 (en) 2005-09-28
WO2004059278A3 (en) 2005-03-03
WO2004059278A8 (en) 2004-09-02

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20050622

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20080729

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20081104