EP1572724A4 - Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy - Google Patents
Kdr and vegf/kdr binding peptides and their use in diagnosis and therapyInfo
- Publication number
- EP1572724A4 EP1572724A4 EP03711418A EP03711418A EP1572724A4 EP 1572724 A4 EP1572724 A4 EP 1572724A4 EP 03711418 A EP03711418 A EP 03711418A EP 03711418 A EP03711418 A EP 03711418A EP 1572724 A4 EP1572724 A4 EP 1572724A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- kdr
- vegf
- diagnosis
- therapy
- binding peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 101100372758 Danio rerio vegfaa gene Proteins 0.000 title 1
- 101150030763 Vegfa gene Proteins 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- AIDS & HIV (AREA)
- Physical Education & Sports Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Acoustics & Sound (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10185498.2A EP2301587B1 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis |
EP08008365A EP2014310B8 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36085102P | 2002-03-01 | 2002-03-01 | |
US360851P | 2002-03-01 | ||
US44041103P | 2003-01-15 | 2003-01-15 | |
US440411P | 2003-01-15 | ||
PCT/US2003/006731 WO2003074005A2 (en) | 2002-03-01 | 2003-03-03 | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10185498.2A Division EP2301587B1 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis |
EP08008365A Division EP2014310B8 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1572724A2 EP1572724A2 (en) | 2005-09-14 |
EP1572724A4 true EP1572724A4 (en) | 2007-03-14 |
Family
ID=27791656
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10185498.2A Expired - Lifetime EP2301587B1 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis |
EP08008365A Expired - Lifetime EP2014310B8 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
EP03711418A Withdrawn EP1572724A4 (en) | 2002-03-01 | 2003-03-03 | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10185498.2A Expired - Lifetime EP2301587B1 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis |
EP08008365A Expired - Lifetime EP2014310B8 (en) | 2002-03-01 | 2003-03-03 | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
Country Status (7)
Country | Link |
---|---|
EP (3) | EP2301587B1 (en) |
JP (2) | JP2006514915A (en) |
AU (2) | AU2003213730A1 (en) |
CA (2) | CA2477836A1 (en) |
ES (2) | ES2398393T3 (en) |
SI (1) | SI2301587T1 (en) |
WO (1) | WO2003074005A2 (en) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4336771B2 (en) | 2001-03-09 | 2009-09-30 | モルフォシス アーゲー | Serum albumin binding moiety |
US7666979B2 (en) * | 2002-03-01 | 2010-02-23 | Bracco International B.V. | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
CA2477935C (en) * | 2002-03-01 | 2015-01-06 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
US20050250700A1 (en) * | 2002-03-01 | 2005-11-10 | Sato Aaron K | KDR and VEGF/KDR binding peptides |
US7211240B2 (en) | 2002-03-01 | 2007-05-01 | Bracco International B.V. | Multivalent constructs for therapeutic and diagnostic applications |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
WO2004065621A1 (en) | 2002-03-01 | 2004-08-05 | Dyax Corp. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
NO20026286D0 (en) * | 2002-12-30 | 2002-12-30 | Amersham Health As | New peptides |
KR101076053B1 (en) | 2003-02-04 | 2011-10-21 | 브라코 인터내셔날 비.브이. | Ultrasound contrast agents and process for the preparation thereof |
EP2662087A1 (en) * | 2003-04-22 | 2013-11-13 | Ipsen Pharma | Somatostatin vectors |
AU2004308756B2 (en) | 2003-12-22 | 2010-06-24 | Bracco Suisse S.A. | Gas-filled microvesicle assembly for contrast imaging |
CN1960707B (en) | 2004-06-03 | 2012-11-14 | 博莱科瑞士股份有限公司 | Liposomal assembly for therapeutic and/or diagnostic use |
JP4837663B2 (en) | 2004-08-18 | 2011-12-14 | ブラッコ・シュイス・ソシエテ・アノニム | Gas-filled microvesicle composition for contrast imaging |
EP1846015A4 (en) * | 2005-01-19 | 2009-08-12 | Mathew Mark Zuckerman | Method, compositions and classification for tumor diagnostics and treatment |
EP1714642A1 (en) | 2005-04-18 | 2006-10-25 | Bracco Research S.A. | Pharmaceutical composition comprising gas-filled microcapsules for ultrasound mediated delivery |
CN103204911B (en) * | 2005-12-09 | 2015-04-01 | 布拉科瑞士有限公司 | Targeting Vector-phospholipid Conjugates |
EP2061517B1 (en) | 2006-09-05 | 2010-06-02 | Bracco Research S.A. | Gas-filled microvesicles with polymer-modified lipids |
WO2008075192A2 (en) * | 2006-12-19 | 2008-06-26 | Bracco International Bv | Targeting and therapeutic compounds and gas-filled microvesicles comprising said com ounds |
CA2748995C (en) | 2008-10-07 | 2018-01-16 | Bracco Suisse Sa | Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same |
WO2011046991A2 (en) * | 2009-10-15 | 2011-04-21 | Gilead Connecticut, Inc. | Certain substituted ureas as modulators of kinase activity |
WO2014096165A2 (en) | 2012-12-21 | 2014-06-26 | Bracco Suisse Sa | Gas-filled microvesicles |
BE1021191B1 (en) | 2014-08-29 | 2015-10-27 | Anmi S.A. | KIT FOR RADIOMARKING. |
US11027030B2 (en) | 2014-08-29 | 2021-06-08 | Anmi S.A. | Kit for radiolabelling |
JP6803839B2 (en) | 2014-12-18 | 2020-12-23 | ブラッコ・スイス・ソシエテ・アノニムBracco Suisse SA | Formulation of targeted gas-filled microvesicles |
EP3308779B1 (en) * | 2015-06-10 | 2019-08-07 | Teikyo University | Theranostic bubble preparation (tb), and method for using same |
TR201723077A2 (en) * | 2017-12-29 | 2019-07-22 | Ege Ueniversitesi | ULTRACE SENSITIVE MAGNETIC TARGET NANO DRUG CARRIER SYSTEM |
US20200360289A1 (en) | 2019-05-15 | 2020-11-19 | Bracco Suisse Sa | Freeze-dried product and gas-filled microvesicles suspension |
US11717570B2 (en) | 2019-05-15 | 2023-08-08 | Bracco Suisse Sa | Gas-filled microvesicles |
CA3187052A1 (en) | 2020-07-29 | 2022-02-03 | Eddy Sotelo Perez | Functionalized isonitriles and products, preparation and uses thereof |
CN113740539B (en) * | 2021-08-11 | 2023-07-25 | 中元汇吉生物技术股份有限公司 | Kit for determining specific growth factors |
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Also Published As
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EP1572724A2 (en) | 2005-09-14 |
SI2301587T1 (en) | 2014-11-28 |
ES2506142T3 (en) | 2014-10-13 |
AU2003213730A1 (en) | 2003-09-16 |
EP2301587A3 (en) | 2011-04-06 |
JP2006514915A (en) | 2006-05-18 |
EP2014310A3 (en) | 2009-09-09 |
CA2477836A1 (en) | 2003-09-12 |
AU2009201114B2 (en) | 2012-01-19 |
EP2301587B1 (en) | 2014-06-25 |
CA2666005C (en) | 2016-01-19 |
EP2014310B1 (en) | 2012-10-24 |
CA2666005A1 (en) | 2003-09-12 |
JP5039075B2 (en) | 2012-10-03 |
WO2003074005A8 (en) | 2005-07-21 |
EP2014310A2 (en) | 2009-01-14 |
EP2014310B8 (en) | 2012-12-26 |
WO2003074005A2 (en) | 2003-09-12 |
JP2009161549A (en) | 2009-07-23 |
EP2301587A2 (en) | 2011-03-30 |
ES2398393T3 (en) | 2013-03-15 |
AU2009201114A1 (en) | 2009-04-09 |
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