EP1572724A4 - Peptides liant des recepteurs kdr et vegf/kdr et leurs utilisations en diagnostic et therapie - Google Patents

Peptides liant des recepteurs kdr et vegf/kdr et leurs utilisations en diagnostic et therapie

Info

Publication number
EP1572724A4
EP1572724A4 EP03711418A EP03711418A EP1572724A4 EP 1572724 A4 EP1572724 A4 EP 1572724A4 EP 03711418 A EP03711418 A EP 03711418A EP 03711418 A EP03711418 A EP 03711418A EP 1572724 A4 EP1572724 A4 EP 1572724A4
Authority
EP
European Patent Office
Prior art keywords
kdr
vegf
diagnosis
therapy
binding peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03711418A
Other languages
German (de)
English (en)
Other versions
EP1572724A2 (fr
Inventor
Aaron K Sato
Daniel J Sexton
Robert C Ladner
Daniel T Dransfield
Rolf E Swenson
Edmund R Marinelli
Kondareddiar Ramalingam
Adrian D Nunn
Wronski Mathew A Von
Ajay Shrivastava
Sibylle Pochon
Philippe Bussat
Christophe Arbogast
Radhakrishna Pillai
Hong Fan
Karen E Linder
Bo Song
Palaniappa Nanjappan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco International BV
Dyax Corp
Original Assignee
Bracco International BV
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco International BV, Dyax Corp filed Critical Bracco International BV
Priority to EP08008365A priority Critical patent/EP2014310B8/fr
Priority to EP10185498.2A priority patent/EP2301587B1/fr
Publication of EP1572724A2 publication Critical patent/EP1572724A2/fr
Publication of EP1572724A4 publication Critical patent/EP1572724A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP03711418A 2002-03-01 2003-03-03 Peptides liant des recepteurs kdr et vegf/kdr et leurs utilisations en diagnostic et therapie Withdrawn EP1572724A4 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP08008365A EP2014310B8 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie
EP10185498.2A EP2301587B1 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36085102P 2002-03-01 2002-03-01
US360851P 2002-03-01
US44041103P 2003-01-15 2003-01-15
US440411P 2003-01-15
PCT/US2003/006731 WO2003074005A2 (fr) 2002-03-01 2003-03-03 Peptides liant des recepteurs kdr et vegf/kdr et leurs utilisations en diagnostic et therapie

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP10185498.2A Division EP2301587B1 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie
EP08008365A Division EP2014310B8 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie

Publications (2)

Publication Number Publication Date
EP1572724A2 EP1572724A2 (fr) 2005-09-14
EP1572724A4 true EP1572724A4 (fr) 2007-03-14

Family

ID=27791656

Family Applications (3)

Application Number Title Priority Date Filing Date
EP10185498.2A Expired - Lifetime EP2301587B1 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie
EP03711418A Withdrawn EP1572724A4 (fr) 2002-03-01 2003-03-03 Peptides liant des recepteurs kdr et vegf/kdr et leurs utilisations en diagnostic et therapie
EP08008365A Expired - Lifetime EP2014310B8 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP10185498.2A Expired - Lifetime EP2301587B1 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP08008365A Expired - Lifetime EP2014310B8 (fr) 2002-03-01 2003-03-03 Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie

Country Status (7)

Country Link
EP (3) EP2301587B1 (fr)
JP (2) JP2006514915A (fr)
AU (2) AU2003213730A1 (fr)
CA (2) CA2477836A1 (fr)
ES (2) ES2398393T3 (fr)
SI (1) SI2301587T1 (fr)
WO (1) WO2003074005A2 (fr)

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US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
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US7666979B2 (en) * 2002-03-01 2010-02-23 Bracco International B.V. Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same
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US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
CA2477935C (fr) * 2002-03-01 2015-01-06 Bracco International Bv Produits de synthese multivalents pour applications therapeutiques et diagnostiques
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US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
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TR201723077A2 (tr) * 2017-12-29 2019-07-22 Ege Ueniversitesi Ultrases duyarli manyeti̇k hedefli̇ nano i̇laç taşiyici si̇stem
US20200360289A1 (en) 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension
US11717570B2 (en) 2019-05-15 2023-08-08 Bracco Suisse Sa Gas-filled microvesicles
EP4178948A2 (fr) 2020-07-29 2023-05-17 Universidade de Santiago de Compostela Isonitriles fonctionnalisés et produits associés, leur préparation et leurs utilisations
CN113740539B (zh) * 2021-08-11 2023-07-25 中元汇吉生物技术股份有限公司 一种测定特异性生长因子的试剂盒

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AU2009201114B2 (en) 2012-01-19
EP2301587B1 (fr) 2014-06-25
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EP1572724A2 (fr) 2005-09-14
EP2014310B1 (fr) 2012-10-24
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EP2014310A2 (fr) 2009-01-14
AU2003213730A1 (en) 2003-09-16
SI2301587T1 (sl) 2014-11-28
EP2301587A2 (fr) 2011-03-30
WO2003074005A2 (fr) 2003-09-12
WO2003074005A8 (fr) 2005-07-21
AU2009201114A1 (en) 2009-04-09
EP2301587A3 (fr) 2011-04-06
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