EP1549761A4 - Methods and compositions for the modification of nucleic acids - Google Patents

Methods and compositions for the modification of nucleic acids

Info

Publication number
EP1549761A4
EP1549761A4 EP03726696A EP03726696A EP1549761A4 EP 1549761 A4 EP1549761 A4 EP 1549761A4 EP 03726696 A EP03726696 A EP 03726696A EP 03726696 A EP03726696 A EP 03726696A EP 1549761 A4 EP1549761 A4 EP 1549761A4
Authority
EP
European Patent Office
Prior art keywords
compositions
modification
methods
nucleic acids
nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03726696A
Other languages
German (de)
French (fr)
Other versions
EP1549761A1 (en
Inventor
Kevin Plunkett
Andrei Purmal
Boris Zavizion
John Chapman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VI Technologies Inc
Original Assignee
VI Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VI Technologies Inc filed Critical VI Technologies Inc
Publication of EP1549761A1 publication Critical patent/EP1549761A1/en
Publication of EP1549761A4 publication Critical patent/EP1549761A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/12Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14311Parvovirus, e.g. minute virus of mice
    • C12N2750/14361Methods of inactivation or attenuation
    • C12N2750/14363Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03726696A 2002-05-06 2003-05-06 Methods and compositions for the modification of nucleic acids Withdrawn EP1549761A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37818402P 2002-05-06 2002-05-06
US378184P 2002-05-06
PCT/US2003/014363 WO2003093512A1 (en) 2002-05-06 2003-05-06 Methods and compositions for the modification of nucleic acids

Publications (2)

Publication Number Publication Date
EP1549761A1 EP1549761A1 (en) 2005-07-06
EP1549761A4 true EP1549761A4 (en) 2006-02-15

Family

ID=29401590

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03726696A Withdrawn EP1549761A4 (en) 2002-05-06 2003-05-06 Methods and compositions for the modification of nucleic acids

Country Status (5)

Country Link
EP (1) EP1549761A4 (en)
JP (1) JP2005524707A (en)
AU (1) AU2003228919A1 (en)
CA (1) CA2484940A1 (en)
WO (1) WO2003093512A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040053208A1 (en) * 1995-08-29 2004-03-18 V. I. TECHNOLOGIES, Inc. Methods to selectively inactivate parasites in biological compositions
CA3107314A1 (en) * 2018-07-27 2020-01-30 Zata Pharmaceuticals, Inc. Method for pathogens, microorganisms, and parasites inactivation
CN112342144B (en) * 2020-09-28 2023-02-14 江西农业大学 Aspergillus flavus strain and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044720A1 (en) * 1999-01-29 2000-08-03 V.I. Technologies, Inc. Synthesis of ethyleneimine dimer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352695B1 (en) * 1997-10-03 2002-03-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids
US6093564A (en) * 1997-10-03 2000-07-25 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044720A1 (en) * 1999-01-29 2000-08-03 V.I. Technologies, Inc. Synthesis of ethyleneimine dimer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PIPER J R ET AL: "S-2-(OMEGA-AMINOALKYLAMINO)ETHYL DIHYDROGEN PHOSPHOROTIOATES AND RELATED COMPOUNDS AS POTENTIAL ANTIRADIATION AGENTS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 12, 1969, pages 236 - 243, XP001061529, ISSN: 0022-2623 *
See also references of WO03093512A1 *
YUAN ET AL: "Cytotoxic activity of N1- and N-8-aziridinyl analogs of spermidine", BIOCHEMICAL PHARMACOLOGY, vol. 47, no. 9, 1994, GREAT BRITAIN, pages 1587 - 1592, XP002358851 *

Also Published As

Publication number Publication date
JP2005524707A (en) 2005-08-18
EP1549761A1 (en) 2005-07-06
WO2003093512A1 (en) 2003-11-13
CA2484940A1 (en) 2003-11-13
AU2003228919A1 (en) 2003-11-17

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20041203

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
RBV Designated contracting states (corrected)

Designated state(s): DE FR GB

RIC1 Information provided on ipc code assigned before grant

Ipc: C07D 203/12 20060101ALI20051220BHEP

Ipc: C07H 21/00 20060101ALI20051220BHEP

Ipc: C12Q 1/68 20060101AFI20031119BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20051230

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20051201

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CHAPMAN, JOHN

Inventor name: ZAVIZION, BORIS

Inventor name: PURMAL, ANDREI, A.

Inventor name: PLUNKETT, KEVIN