EP1537239A4 - Verfahren zur identifizierung von proteinaktivität modulierenden verbindungen - Google Patents

Verfahren zur identifizierung von proteinaktivität modulierenden verbindungen

Info

Publication number
EP1537239A4
EP1537239A4 EP03767213A EP03767213A EP1537239A4 EP 1537239 A4 EP1537239 A4 EP 1537239A4 EP 03767213 A EP03767213 A EP 03767213A EP 03767213 A EP03767213 A EP 03767213A EP 1537239 A4 EP1537239 A4 EP 1537239A4
Authority
EP
European Patent Office
Prior art keywords
methods
protein activity
identifying compounds
modulate protein
modulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03767213A
Other languages
English (en)
French (fr)
Other versions
EP1537239A2 (de
Inventor
Constance Berghs
Karen Ellerman
Xiaojia Guo
Li Li
Tatiana Ort
Daniel K Rieger
Corine A M Vernet
Mei Zhong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
CuraGen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/307,817 external-priority patent/US20040058338A1/en
Application filed by CuraGen Corp filed Critical CuraGen Corp
Priority claimed from PCT/US2003/024504 external-priority patent/WO2004013347A2/en
Publication of EP1537239A2 publication Critical patent/EP1537239A2/de
Publication of EP1537239A4 publication Critical patent/EP1537239A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP03767213A 2002-08-06 2003-08-06 Verfahren zur identifizierung von proteinaktivität modulierenden verbindungen Withdrawn EP1537239A4 (de)

Applications Claiming Priority (43)

Application Number Priority Date Filing Date Title
US307817 1989-02-07
US40131602P 2002-08-06 2002-08-06
US40162702P 2002-08-06 2002-08-06
US40131502P 2002-08-06 2002-08-06
US401627P 2002-08-06
US401315P 2002-08-06
US401316P 2002-08-06
US40178802P 2002-08-07 2002-08-07
US401788P 2002-08-07
US40362002P 2002-08-15 2002-08-15
US403620P 2002-08-15
US40467602P 2002-08-20 2002-08-20
US40464902P 2002-08-20 2002-08-20
US40467402P 2002-08-20 2002-08-20
US404676P 2002-08-20
US404649P 2002-08-20
US404674P 2002-08-20
US40523202P 2002-08-22 2002-08-22
US40512102P 2002-08-22 2002-08-22
US405232P 2002-08-22
US405121P 2002-08-22
US40540002P 2002-08-23 2002-08-23
US40568402P 2002-08-23 2002-08-23
US40568702P 2002-08-23 2002-08-23
US40569802P 2002-08-23 2002-08-23
US405684P 2002-08-23
US405687P 2002-08-23
US405698P 2002-08-23
US405400P 2002-08-23
US40635302P 2002-08-26 2002-08-26
US406353P 2002-08-26
US40613002P 2002-08-27 2002-08-27
US40613102P 2002-08-27 2002-08-27
US406131P 2002-08-27
US406130P 2002-08-27
US40791902P 2002-09-03 2002-09-03
US407919P 2002-09-03
US40936602P 2002-09-09 2002-09-09
US409366P 2002-09-09
US42275602P 2002-10-31 2002-10-31
US422756P 2002-10-31
US10/307,817 US20040058338A1 (en) 2001-12-03 2002-12-02 Novel proteins and nucleic acids encoding same
PCT/US2003/024504 WO2004013347A2 (en) 2002-08-06 2003-08-06 Methods of identifying compounds that modulate protein activity

Publications (2)

Publication Number Publication Date
EP1537239A2 EP1537239A2 (de) 2005-06-08
EP1537239A4 true EP1537239A4 (de) 2007-02-07

Family

ID=31499768

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03767213A Withdrawn EP1537239A4 (de) 2002-08-06 2003-08-06 Verfahren zur identifizierung von proteinaktivität modulierenden verbindungen

Country Status (4)

Country Link
EP (1) EP1537239A4 (de)
JP (1) JP2006511237A (de)
AU (1) AU2003263992A1 (de)
CA (1) CA2495123A1 (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187545B1 (en) * 2000-01-19 2001-02-13 Isis Pharmaceuticals Inc. Antisense modulation of pepck-cytosolic expression

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187545B1 (en) * 2000-01-19 2001-02-13 Isis Pharmaceuticals Inc. Antisense modulation of pepck-cytosolic expression

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 12 February 2002 (2002-02-12), "Homo sapiens phosphoenolpyruvate carboxykinase 1(soluble), mRNA (cDNA) clone MGC:22652 IMAGE:4042259), complete cds.", XP002392704, retrieved from EBI Database accession no. BC023978 *
HAYASHI TAIZO ET AL: "A new stroke marker as detected by serum phosphoglycerate mutase B-type isozyme", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 287, no. 4, 5 October 2001 (2001-10-05), pages 843 - 845, XP002392703, ISSN: 0006-291X *
HIDA KAZUYUKI ET AL: "Identification of genes specifically expressed in the accumulated visceral adipose tissue of OLETF rats", JOURNAL OF LIPID RESEARCH, vol. 41, no. 10, October 2000 (2000-10-01), pages 1615 - 1622, XP002392700, ISSN: 0022-2275 *
LI JINPING ET AL: "Gene expression profile of rat adipose tissue at the onset of high-fat-diet obesity.", AMERICAN JOURNAL OF PHYSIOLOGY. ENDOCRINOLOGY AND METABOLISM. JUN 2002, vol. 282, no. 6, June 2002 (2002-06-01), pages E1334 - E1341, XP002392705, ISSN: 0193-1849 *
LOCHHEAD PAMELA A ET AL: "5-Aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase", DIABETES, vol. 49, no. 6, June 2000 (2000-06-01), pages 896 - 903, XP002392701, ISSN: 0012-1797 *
OLSWANG YAEL ET AL: "A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, no. 2, 22 January 2002 (2002-01-22), pages 625 - 630, XP002392702, ISSN: 0027-8424 *
SHIMKETS R A ET AL: "Gene expression analysis by transcript profiling coupled to a gene database query.", NATURE BIOTECHNOLOGY. AUG 1999, vol. 17, no. 8, August 1999 (1999-08-01), pages 798 - 803, XP002130008, ISSN: 1087-0156 *
SPENTZOS D ET AL: "TRANSKETOLASE GENE EXPRESSION MAY BE A MARKER OF SENSITIVITY TO PLATINUM/PACLITAXEL CHEMOTHERAPY IN OVARIAN CANCER", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, NEW YORK, NY, US, vol. 43, March 2002 (2002-03-01), pages 1105 - 1106, XP008012309, ISSN: 0197-016X *
VALERA ET AL: "Regulated expression of human insulin in the liver of transgenic mice corrects diabetic alterations", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, BETHESDA, MD, US, vol. 8, no. 8, April 1994 (1994-04-01), pages 440 - 447, XP002098530, ISSN: 0892-6638 *

Also Published As

Publication number Publication date
CA2495123A1 (en) 2004-02-12
JP2006511237A (ja) 2006-04-06
AU2003263992A1 (en) 2004-02-23
EP1537239A2 (de) 2005-06-08

Similar Documents

Publication Publication Date Title
AP2004003135A0 (en) Compounds that modulate PPAR activity and methods for their preparation
AU2003209060A8 (en) Assay for acytyltransferase or deacetylase activity
SI1561756T1 (sl) Postopek čiščenja proteinov
GB0322989D0 (en) Method of deriving data
AU2003299592A8 (en) Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2
IL165201A0 (en) Application of loading ledges
AU2003252072A8 (en) Modulation of protein kinase c-iota expression
AU2003297700A8 (en) Methods for modulating ikkalpha activity
EP1532173A4 (de) Proteinanalyse
AU2003282338A8 (en) Determination of protein function
AU2003241375A8 (en) Method for identifying modulators of sulfotransferase activity
WO2004056961A9 (en) Methods of identifying compounds that modulate protein activity
AU2003297808A8 (en) Peptides and methods for deactivation of organophosphorus-based nerve agents and insecticides
AU2003206594A8 (en) Screening for modulators of pkng activity
AU2003303381A8 (en) Methods for treating malaria by modulation of g protein function
WO2006020326A9 (en) Methods of identifying compounds that modulate protein activity
AU2003241335A8 (en) Method of analyzing ataxia-telangiectasia protein
GB0201808D0 (en) Protein
GB0611250D0 (en) Method of analyzing protein
AU2003293581A8 (en) Method of identifying therapeutic agents
AU2003246861A1 (en) Use of agents that modulate pde11a activity
PL376318A1 (en) Protein modification
GB0328690D0 (en) Tumour suppressor protein
AU2003218029A8 (en) Methods of identifying target polypeptides
AU2003278718A8 (en) Stars-a muscle-specification-binding protein

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20050304

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CURAGEN CORPORATION

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20070110

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070301