EP1501917A2 - Device and method for analytical cell imaging - Google Patents
Device and method for analytical cell imagingInfo
- Publication number
- EP1501917A2 EP1501917A2 EP03728685A EP03728685A EP1501917A2 EP 1501917 A2 EP1501917 A2 EP 1501917A2 EP 03728685 A EP03728685 A EP 03728685A EP 03728685 A EP03728685 A EP 03728685A EP 1501917 A2 EP1501917 A2 EP 1501917A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- cells
- illumination
- sample
- group
- sample chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
-
- G01N15/1433—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37786802P | 2002-05-03 | 2002-05-03 | |
US377868P | 2002-05-03 | ||
PCT/US2003/013842 WO2003093795A2 (en) | 2002-05-03 | 2003-05-05 | Device and method for analytical cell imaging |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1501917A2 true EP1501917A2 (en) | 2005-02-02 |
EP1501917A4 EP1501917A4 (en) | 2006-04-19 |
Family
ID=29401578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03728685A Withdrawn EP1501917A4 (en) | 2002-05-03 | 2003-05-05 | Device and method for analytical cell imaging |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1501917A4 (en) |
JP (1) | JP2005524833A (en) |
AU (1) | AU2003234459A1 (en) |
CA (1) | CA2484730A1 (en) |
WO (1) | WO2003093795A2 (en) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004029221A2 (en) | 2002-09-27 | 2004-04-08 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
JP4041458B2 (en) * | 2003-12-12 | 2008-01-30 | 日立ソフトウエアエンジニアリング株式会社 | Fluorescent bead detection method and fluorescent bead detection device |
US7468796B2 (en) | 2004-08-06 | 2008-12-23 | Compucyte Corporation | Multiple-color monochromatic light absorption and quantification of light absorption in a stained sample |
BRPI0517442A (en) * | 2004-10-22 | 2008-10-07 | Fermiscan Australia Pty Ltd | analytical method and apparatus |
US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US9134237B2 (en) * | 2005-09-20 | 2015-09-15 | Janssen Diagnotics, LLC | High sensitivity multiparameter method for rare event analysis in a biological sample |
CA2623405C (en) | 2005-09-20 | 2014-11-25 | Immunivest Corporation | Methods and composition to generate unique sequence dna probes labeling of dna probes and the use of these probes |
FI20051329A0 (en) | 2005-12-27 | 2005-12-27 | Wallac Oy | Apparatus and method for optical measurement of samples |
WO2007133465A2 (en) * | 2006-05-12 | 2007-11-22 | Immunivest Corporation | A laser illumination system in fluorescent microscopy |
US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
WO2007147074A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Use of highly parallel snp genotyping for fetal diagnosis |
WO2008012724A2 (en) * | 2006-07-20 | 2008-01-31 | Koninklijke Philips Electronics N.V. | Optical tracking and position determination for detection methods and systems |
US7782452B2 (en) * | 2007-08-31 | 2010-08-24 | Kla-Tencor Technologies Corp. | Systems and method for simultaneously inspecting a specimen with two distinct channels |
US8143600B2 (en) * | 2008-02-18 | 2012-03-27 | Visiongate, Inc. | 3D imaging of live cells with ultraviolet radiation |
CA3069081C (en) | 2008-09-20 | 2023-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
JP5119114B2 (en) * | 2008-09-30 | 2013-01-16 | 富士フイルム株式会社 | Light source device and photographing device |
JP4805418B1 (en) * | 2010-03-31 | 2011-11-02 | 古河電気工業株式会社 | Cell identification device and identification method |
CN103562728B (en) | 2011-03-24 | 2016-08-17 | 安派科生物医学科技有限公司 | Micro element for disease detection |
CN106995780B (en) | 2011-05-05 | 2019-11-22 | 安派科生物医学科技有限公司 | Tumour cell detector |
US20130157347A1 (en) * | 2011-07-07 | 2013-06-20 | Veridex, Llc | Method of Analyzing Cardiovascular Disorders and Uses Thereof |
US9511152B2 (en) * | 2012-04-05 | 2016-12-06 | The Board Of Regents Of The University Of Texas System | Multicolored pH-activatable fluorescence nanoplatform |
CN104914078A (en) * | 2015-04-16 | 2015-09-16 | 南京昊控软件技术有限公司 | Large-range multi-point fluid concentration measuring system |
US11226271B2 (en) * | 2016-03-07 | 2022-01-18 | X-Zell Biotech Pte Ltd | Systems and methods for identifying rare cells |
FR3051556A1 (en) * | 2016-05-18 | 2017-11-24 | Biocytex | USE OF FLUORESCENT MARKERS FOR THE DETECTION OF BIOLOGICAL TARGET IN A SAMPLE |
Family Cites Families (5)
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US5034613A (en) * | 1989-11-14 | 1991-07-23 | Cornell Research Foundation, Inc. | Two-photon laser microscopy |
US5127730A (en) * | 1990-08-10 | 1992-07-07 | Regents Of The University Of Minnesota | Multi-color laser scanning confocal imaging system |
US5698397A (en) * | 1995-06-07 | 1997-12-16 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
JP3343276B2 (en) * | 1993-04-15 | 2002-11-11 | 興和株式会社 | Laser scanning optical microscope |
US5479252A (en) * | 1993-06-17 | 1995-12-26 | Ultrapointe Corporation | Laser imaging system for inspection and analysis of sub-micron particles |
-
2003
- 2003-05-05 EP EP03728685A patent/EP1501917A4/en not_active Withdrawn
- 2003-05-05 AU AU2003234459A patent/AU2003234459A1/en not_active Abandoned
- 2003-05-05 WO PCT/US2003/013842 patent/WO2003093795A2/en not_active Application Discontinuation
- 2003-05-05 CA CA002484730A patent/CA2484730A1/en not_active Abandoned
- 2003-05-05 JP JP2004501911A patent/JP2005524833A/en active Pending
Non-Patent Citations (3)
Title |
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KAGAN M ET AL: "CellTracks Cell Analysis System for Rare Cell Detection" PROC. SPIE, CONF. CLINICAL DIAGNOSTIC SYSTEMS: TECHNOLOGIES AND INSTRUMENTATION, 22-24 JAN. 2002, SAN JOSE, CA, USA, vol. 4625, June 2002 (2002-06), pages 20-28, XP002368763 * |
See also references of WO03093795A2 * |
TIBBE A G J ET AL: "Imaging Technique Implemented in CellTracks System" CYTOMETRY, vol. 47, 1 April 2002 (2002-04-01), pages 248-255, XP002368764 published online 21 March 2002 * |
Also Published As
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EP1501917A4 (en) | 2006-04-19 |
AU2003234459A8 (en) | 2003-11-17 |
WO2003093795A3 (en) | 2004-10-21 |
WO2003093795A2 (en) | 2003-11-13 |
CA2484730A1 (en) | 2003-11-13 |
AU2003234459A1 (en) | 2003-11-17 |
JP2005524833A (en) | 2005-08-18 |
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