EP1480995A4 - Cks1 INHIBITORS - Google Patents

Cks1 INHIBITORS

Info

Publication number
EP1480995A4
EP1480995A4 EP03711050A EP03711050A EP1480995A4 EP 1480995 A4 EP1480995 A4 EP 1480995A4 EP 03711050 A EP03711050 A EP 03711050A EP 03711050 A EP03711050 A EP 03711050A EP 1480995 A4 EP1480995 A4 EP 1480995A4
Authority
EP
European Patent Office
Prior art keywords
cks1
inhibitors
cks1 inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03711050A
Other languages
German (de)
French (fr)
Other versions
EP1480995A2 (en
Inventor
Annette O Walter
Christoph Reinhard
Anne B Jefferson
Blanche-Marie F Shamoon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of EP1480995A2 publication Critical patent/EP1480995A2/en
Publication of EP1480995A4 publication Critical patent/EP1480995A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP03711050A 2002-02-12 2003-02-12 Cks1 INHIBITORS Withdrawn EP1480995A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35690602P 2002-02-12 2002-02-12
US356906P 2002-02-12
PCT/US2003/004550 WO2003068939A2 (en) 2002-02-12 2003-02-12 Cks1 INHIBITORS

Publications (2)

Publication Number Publication Date
EP1480995A2 EP1480995A2 (en) 2004-12-01
EP1480995A4 true EP1480995A4 (en) 2006-09-13

Family

ID=27734702

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03711050A Withdrawn EP1480995A4 (en) 2002-02-12 2003-02-12 Cks1 INHIBITORS

Country Status (5)

Country Link
EP (1) EP1480995A4 (en)
JP (1) JP2005523280A (en)
AU (1) AU2003215235A1 (en)
CA (1) CA2474844A1 (en)
WO (1) WO2003068939A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2954896A1 (en) * 2014-06-13 2015-12-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Small molecule inhibitors of the E3 Ligase Skp2 in depression and other diseases

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997011176A2 (en) * 1995-09-21 1997-03-27 Cold Spring Harbor Laboratory Cyclin/cdk associated proteins, and uses related thereto
WO2002055665A2 (en) * 2001-01-05 2002-07-18 Univ New York Methods to identify compounds useful for the treatment of proliferative and differentiative disorders
WO2002068444A1 (en) * 2001-02-21 2002-09-06 Chiron Corporation Ttk in diagnosis and as a therapeutic target in cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801015A (en) * 1995-06-05 1998-09-01 Mitotix, Inc. Nucleic acid encoding a Candida cell cycle regulatory protein, TYP1 polypeptide
CA2284136C (en) * 1997-03-14 2009-02-10 Cropdesign N.V. Method and means for modulating plant cell cycle proteins and their use in plant cell growth control
US6573094B1 (en) * 1997-10-16 2003-06-03 Baylor College Of Medicine F-box genes and proteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997011176A2 (en) * 1995-09-21 1997-03-27 Cold Spring Harbor Laboratory Cyclin/cdk associated proteins, and uses related thereto
WO2002055665A2 (en) * 2001-01-05 2002-07-18 Univ New York Methods to identify compounds useful for the treatment of proliferative and differentiative disorders
WO2002068444A1 (en) * 2001-02-21 2002-09-06 Chiron Corporation Ttk in diagnosis and as a therapeutic target in cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SMITH J P ET AL: "Antisense oligonucleotides to gastrin inhibit growth of human pancreatic cancer", CANCER LETTERS, NEW YORK, NY, US, vol. 135, no. 1, 8 January 1999 (1999-01-08), pages 107 - 112, XP002357825, ISSN: 0304-3835 *
WADE HARPER J: "Protein destruction: Adapting roles for Cks proteins", CURRENT BIOLOGY, vol. 11, no. 11, 2001, pages R432 - R435, XP002391696 *

Also Published As

Publication number Publication date
CA2474844A1 (en) 2003-08-21
WO2003068939A2 (en) 2003-08-21
EP1480995A2 (en) 2004-12-01
WO2003068939A3 (en) 2003-12-31
AU2003215235A1 (en) 2003-09-04
JP2005523280A (en) 2005-08-04
AU2003215235A8 (en) 2003-09-04

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040907

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20060727BHEP

Ipc: A61K 48/00 20060101ALI20060727BHEP

Ipc: C07H 21/02 20060101ALI20060727BHEP

Ipc: C07H 21/04 20060101AFI20040915BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20060810

17Q First examination report despatched

Effective date: 20061205

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20091215