EP1478758A4 - Für restenose und atherosklerose anfällig machende polymorphismen in elastin-, fibrillin- und verwandten genen - Google Patents

Für restenose und atherosklerose anfällig machende polymorphismen in elastin-, fibrillin- und verwandten genen

Info

Publication number
EP1478758A4
EP1478758A4 EP03706019A EP03706019A EP1478758A4 EP 1478758 A4 EP1478758 A4 EP 1478758A4 EP 03706019 A EP03706019 A EP 03706019A EP 03706019 A EP03706019 A EP 03706019A EP 1478758 A4 EP1478758 A4 EP 1478758A4
Authority
EP
European Patent Office
Prior art keywords
fibrillin
predisposing
elastin
polymorphisms
restenosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03706019A
Other languages
English (en)
French (fr)
Other versions
EP1478758A1 (de
Inventor
Stephen E Epstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedStar Research Institute
Original Assignee
MedStar Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MedStar Research Institute filed Critical MedStar Research Institute
Publication of EP1478758A1 publication Critical patent/EP1478758A1/de
Publication of EP1478758A4 publication Critical patent/EP1478758A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
EP03706019A 2002-02-01 2003-02-03 Für restenose und atherosklerose anfällig machende polymorphismen in elastin-, fibrillin- und verwandten genen Withdrawn EP1478758A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35288502P 2002-02-01 2002-02-01
US352885P 2002-02-01
PCT/US2003/003001 WO2003064663A1 (en) 2002-02-01 2003-02-03 Polymorphisms in elastin, fibrillin, and related genes as predisposing to restenosis and to atherosclerosis

Publications (2)

Publication Number Publication Date
EP1478758A1 EP1478758A1 (de) 2004-11-24
EP1478758A4 true EP1478758A4 (de) 2006-08-30

Family

ID=27663146

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03706019A Withdrawn EP1478758A4 (de) 2002-02-01 2003-02-03 Für restenose und atherosklerose anfällig machende polymorphismen in elastin-, fibrillin- und verwandten genen

Country Status (3)

Country Link
EP (1) EP1478758A4 (de)
JP (1) JP2005531287A (de)
WO (1) WO2003064663A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU0700024D0 (en) * 2007-01-11 2007-03-28 Mta Szegedi Biolog Koezpont Use of enhancers in biglycan activuty in the preparation of pharmaceutical compositions having utility in cardiac diseases
WO2012005876A2 (en) * 2010-06-30 2012-01-12 Avon Products, Inc. Compositions and methods for stimulating magp-1 to improve the appearance of skin
EP4019035A1 (de) * 2020-12-23 2022-06-29 Institut National De La Sante Et De La Recherche Medicale - Inserm Neue rekombinante fragmente von fibrillin-1 und verwendungsverfahren dafür

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050068A2 (en) * 1999-02-26 2000-08-31 University Of Utah Research Foundation Elastin-based compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050068A2 (en) * 1999-02-26 2000-08-31 University Of Utah Research Foundation Elastin-based compositions

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
LI DEAN Y ET AL: "Elastin is an essential determinant of arterial morphogenesis", NATURE, NATURE PUBLISHING GROUP, LONDON, US, vol. 393, no. 6682, 21 May 1998 (1998-05-21), pages 276 - 280, XP002148309, ISSN: 0028-0836 *
PANETTA C ET AL: "Identification of fibrillins as a major component of coronary atherosclerotic plaques", CARDIOVASCULAR PATHOLOGY 1998 UNITED STATES, vol. 7, no. 2, 1998, pages 69 - 74, XP002389645, ISSN: 1054-8807 *
See also references of WO03064663A1 *
WU K-J ET AL: "CHARACTERIZATION OF DIFFERENTIAL GENE EXPRESSION IN MONKEY ARTERIAL NEOINTIMA FOLLOWING BALLOON CATHETER INJURY", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS, ATHENS, GR, vol. 6, no. 4, October 2000 (2000-10-01), pages 433 - 440, XP008010068, ISSN: 1107-3756 *

Also Published As

Publication number Publication date
EP1478758A1 (de) 2004-11-24
JP2005531287A (ja) 2005-10-20
WO2003064663A1 (en) 2003-08-07

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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AX Request for extension of the european patent

Extension state: AL LT LV MK RO

RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/68 20060101ALI20060712BHEP

Ipc: C12N 15/00 20060101ALI20060712BHEP

Ipc: C12N 15/85 20060101AFI20030813BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20060727

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Effective date: 20061026

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