EP1478746A4 - Hyaluronan synthases and methods of making and using same - Google Patents

Hyaluronan synthases and methods of making and using same

Info

Publication number
EP1478746A4
EP1478746A4 EP02794128A EP02794128A EP1478746A4 EP 1478746 A4 EP1478746 A4 EP 1478746A4 EP 02794128 A EP02794128 A EP 02794128A EP 02794128 A EP02794128 A EP 02794128A EP 1478746 A4 EP1478746 A4 EP 1478746A4
Authority
EP
European Patent Office
Prior art keywords
making
methods
same
hyaluronan synthases
synthases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02794128A
Other languages
German (de)
French (fr)
Other versions
EP1478746A2 (en
Inventor
Paul H Weigel
Kshama Kumari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Oklahoma
University of Texas System
Original Assignee
University of Oklahoma
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/011,771 external-priority patent/US7109011B2/en
Application filed by University of Oklahoma , University of Texas System filed Critical University of Oklahoma
Publication of EP1478746A2 publication Critical patent/EP1478746A2/en
Publication of EP1478746A4 publication Critical patent/EP1478746A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
EP02794128A 2001-12-03 2002-12-03 Hyaluronan synthases and methods of making and using same Withdrawn EP1478746A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11771 1987-02-06
US33610501P 2001-12-03 2001-12-03
US336105P 2001-12-03
US10/011,771 US7109011B2 (en) 1994-07-01 2001-12-11 Hyaluronan synthase gene and uses thereof
PCT/US2002/038596 WO2003048330A2 (en) 2001-12-03 2002-12-03 Hyaluronan synthases and methods of making and using same

Publications (2)

Publication Number Publication Date
EP1478746A2 EP1478746A2 (en) 2004-11-24
EP1478746A4 true EP1478746A4 (en) 2005-06-29

Family

ID=29738612

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02794128A Withdrawn EP1478746A4 (en) 2001-12-03 2002-12-03 Hyaluronan synthases and methods of making and using same

Country Status (5)

Country Link
EP (1) EP1478746A4 (en)
CN (1) CN1596307A (en)
AU (1) AU2002359581B2 (en)
CA (1) CA2469566A1 (en)
WO (1) WO2003048330A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005514059A (en) * 2001-06-13 2005-05-19 ザ ボード オブ リージェンツ オブ ザ ユニヴァーシティー オブ オクラホマ Hyaluronan synthase genes and their expression
CN106680104B (en) * 2016-11-29 2020-04-14 西南石油大学 Dynamic and static rock mechanical parameter correction method and device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423514B1 (en) * 1996-04-22 2002-07-23 Millennium Pharmaceuticals, Inc. Mammalian hyaluronan synthases, nucleic acids and uses thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DEANGELIS P.: "Hyaluronan synthases: fascinating glycosyltransferases from vertebrates, bacterial pathogens, and algal viruses", CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 56, no. 7-8, 15 November 1999 (1999-11-15), pages 670 - 682 *
HELDERMON COY ET AL: "Streptococcal hyaluronan synthases and the synthesis of "designer" hyaluronan", INTERNATIONAL CONGRESS SERIES; NEW FRONTIERS IN MEDICAL SCIENCES: REDEFINING HYALURONAN ELSEVIER SCIENCE B.V. {A}, SARA BURGERHARTSTRAAT 25, 1000 AE, AMSTERDAM, NETHERLANDS SERIES : INTERNATIONAL CONGRESS SERIES (ISSN 0531-5131), 2000, & SYMPOSIUM ON NEW FRONTIERS IN MEDICAL SCIENCES: REDEFINING HYALURONAN; PADUA, ITALY; JUNE 17-19, 1999, pages 41 - 50, XP009047179, ISSN: 0-444-50357-9 *
JING WEI ET AL: "Dissection of the two transferase activities of the Pasteurella multocida hyaluronan synthase: Two active sites exist in one polypeptide", GLYCOBIOLOGY, vol. 10, no. 9, September 2000 (2000-09-01), pages 883 - 889, XP002326785, ISSN: 0959-6658 *
KUMARI KSHAMA ET AL: "The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 16, 19 April 2002 (2002-04-19), pages 13943 - 13951, XP002326787, ISSN: 0021-9258 *
YOSHIDA MAMORU ET AL: "In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 1, 7 January 2000 (2000-01-07), pages 497 - 506, XP002326786, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
AU2002359581A1 (en) 2003-06-17
EP1478746A2 (en) 2004-11-24
WO2003048330A2 (en) 2003-06-12
CA2469566A1 (en) 2003-06-12
CN1596307A (en) 2005-03-16
WO2003048330A3 (en) 2004-09-23
AU2002359581B2 (en) 2008-01-10

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Legal Events

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