EP1423684B1 - Procede et dispositif pour l'analyse de milieu liquide - Google Patents
Procede et dispositif pour l'analyse de milieu liquide Download PDFInfo
- Publication number
- EP1423684B1 EP1423684B1 EP02777005A EP02777005A EP1423684B1 EP 1423684 B1 EP1423684 B1 EP 1423684B1 EP 02777005 A EP02777005 A EP 02777005A EP 02777005 A EP02777005 A EP 02777005A EP 1423684 B1 EP1423684 B1 EP 1423684B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- accordance
- microsensors
- sensor
- fluid medium
- infrared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/72—Investigating presence of flaws
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/20—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
- G01N25/22—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on combustion or catalytic oxidation, e.g. of components of gas mixtures
Definitions
- the present invention relates to a method and a device for analysis of a fluid medium in using an array of microsensors wherein the intensity of the heat radiated by the microsensors is preferably detected externally and decoupled, deviated, and evaluated.
- the present invention relates in particular to the detecting of chemical substances in fluid phases.
- the main problem of many a sensor technology is the translation of a chemical or physical signal of the sensor into an electrical one. Most often, this is effected by the use of photo-elements (optical ⁇ electrical), Piezo crystals (mechanical ⁇ electrical) or semi-conductor cells (thermal orcapacitive ⁇ electrical).
- WO 00/13004 relates to an assembly wherein the amendment of the composition of monomer and co-monomers as well as the addition of other functional molecules (e.g. dyes), inserting into the polymer matrix, may develop and optimize materials with sensor and deviation functionalities.
- the example of inserting dyes as well as the connection with glass-fiber optics describe the development of a sensor assembly for controlling the pH value.
- a further example highlights the use of conducting polymer composites, which may enable the direct redirecting of the figure.
- the problems of conventionally developed sensors appear here in the same way since merely a methodic for accelerated optimization of sensor-analyte interactions by parallel multiple production of various materials is described. This does not describe a new sensor technology.
- US 4,246,228 describes the probably oldest assembly of a sensor for the detection of combustible gases.
- a measuring cell with a glowing wire is connected as an element of a so-called Wheatstone bridge.
- the measuring cell is filled with the analyte gas. If there is a combustion on the wire, the wire's resistance changes, resulting in a current flow of the Wheatstone circuit.
- the current flow is proportional to the concentration of the combustible gas (e.g. a hydrocarbon) in the measuring cell.
- This kind of sensor cannot differentiate between hydrocarbons and hydroxide or carbon monoxide; all molecules are integrally detected.
- the senor element is created by a semi-conductive layer of, e.g., ZnO-Fe 2 O 3 .
- This layer serves as a selective catalyst for the oxidation of hydrocarbons (H 2 or CO are not oxidized!) and as a "translator" of the chemical signal into an electrical one by a change of conductibility in said layer which can be recorded by means of two electrodes.
- US 5,734,091 describes in analogy to US 6,109,095 the design of a nitrogen oxide sensor.
- the active phase of the sensor is in this case a Bi 2 Sr 2 YCu 2 O 8+y .
- the active mass is exposed as the upper layer with regard to the analyte; the diverting is performed by contacted semi-conductor layers, positioned there-below.
- US 5,945,343 describes, as an example, the functionality of a sensor based on the change of the pH value, using an urea sensor:
- the ammonia forming on the sensor surface when the urea is dissolving (induced by the urease enzyme immobilized on the surface) deprotones an indicator molecule INDH+ to IND.
- a change of color (fluorescence detection) is associated with this reaction on the indicator molecule, which is then recorded.
- the most important challenge therein is the stabile immobilization of enzymes as well as indicator molecules. In the present case, this problem is solved by a multi-layer construction of the sensor.
- the core point of US 4,874,500 is the production of a microstructured electrode array, wherein the implementation and contacting is effected from, e.g., the backside of a silicon wafer, divided into fields. Each position can be individually addressed and can selectively be used to detect a component (e.g. in human blood) by means of a cover with a specific sensor layer. By a combination of various sensor materials, a complete analysis of an analyte is possible. The task was obviously defined by diminishing the deviation electrodes and constructing a microstructured wafer system.
- WO 00/36410 shows the complex construction of sensor assemblies even more clearly, based on localized diverting electrodes.
- the high number of sensor materials on the array render in particular signal processing and data management difficult.
- the whole construction cannot be realized but for complex production techniques of microstructuring (etching and masking techniques).
- the disadvantage of known technologies is a complex construction, in particular of the sensor carrier (semi-conductor layers), including the contacting and translation of the sensor signal into an electrical signal as well as the data recording.
- the main problem therein is the diverting of the electrical signal, proportional to the sensor signal.
- thermography As a quick analytic method for testing for catalyst activity.
- the assembly of the instruments e.g. of WO 99/34206 , however, relates to a basically different function of the camera as well as of the choice of materials in the reactor setup than is the case in the present invention. In the present cases, a large number of possible catalysts is merely tested for their activity.
- a thermographic method of gas detection, using one catalyst, is described in GB2198845 .
- one problem of the present invention was to provide a method and a device, making it possible to detect chemical substances in fluid mediums more effectively as well as to simplify the constructive expense of a measuring apparatus used therefore, and to simultaneously diminish or avoid high background noise when diverting an electrical sensor signal.
- the present invention relates to a method and a device for analyzing a fluid medium, as defined in claims 1 and 6.
- Fig. 1 shows the principle construction of the inventive device 10 with a sensor carrier 12, microsensors 14, an infrared transparent window 16, a heating element 18, a casing 20, a fluid inlet 22, an infrared camera 26 and a data processing facility 30.
- the arrows in dotted lines under reference number 28 are the field of view of the infrared camera 26.
- connection element 32 is preferably connected with the data processing facility 30 via a connection element 32.
- the connection element 32 may be any of the connection elements known to the person skilled in the art. Preferably, one or more connection cables are used. Alternatively, the connection element may also be an infrared, radio, or other interface without having direct connection, appropriate for the purpose of data transfer.
- FIG. 2 A preferred embodiment of an array of microsensors 14 in a sensor carrier 12 is shown in Fig. 2 .
- the fluid inlet 22 as well as the fluid outlet 24 are arranged vertically to the section plane in this embodiment and are not shown in this representation.
- Fig. 2 shows the example of a 17 x 9 matrix of microsensors 14.
- the size, form and arrangement of the matrix may generally be chosen arbitrarily, wherein two or three-dimensional matrixes can be used.
- Fig. 3a shows an exchangeable sensor carrier 12 with microsensors 14 in the form of a sandwich unit with infrared transparent window 16 in the cross-section.
- the sensor carrier 12 as well as the infrared transparent window 16 are, in this embodiment, preferably made of silicon, e.g. as a silicon wafer.
- sandwich units are particularly appropriate as exchangeable units, thus increasing the functionality as well as the flexibility of the device 10 as per the invention.
- the microsensors 14 are preferably ceramics balls (carriers, preferably coated with one or more sensor materials).
- a heating element 18 may be preferably provided below the sensor carrier 12.
- the heating element 18 makes various operating temperatures of the sensor device possible.
- Fig. 4a shows a sensor carrier 12, wherein various or equal microsensors 14 are connected in series via channels 34 while they are connected in parallel within the channel.
- the inlet of the fluid medium to the microsensors 14 is therein performed via the fluid inlet 22 and thedischarge via the fluid outlet 24.
- Fig. 4a The embodiment of Fig. 4a is shown in a cross-sectional view in Fig. 4b for better understanding.
- Fig 4b shows only the sensor carrier 12 with the sections 36 provided for receiving the microsensors 14.
- the connection channels 34 between the sections 36 are clearly recognizable.
- this is a sensor carrier 12 or two parts with an upper part 38 and a lower part 40.
- Reference 16 again determines the infrared transparent window, which is preferably provided as silicon wafer or sapphire plate.
- the lower part 40 can be produce of slate for performing the emissivity correction.
- Fig. 5 shows a further possibility of a two-dimensional arrangement of an array of equal or various microsensors 14 on a sensor carrier 12 with fluid inlets 22 and fluid outlets 24.
- a multiport valve circuit in connection with an inventive sensor arrangement is shown in Fig. 6 .
- various fluid mediums are let in via the fluid inlet 22, controlled/regulated by means of a multiport valve 42 switched in front of the fluid inlet 22.
- the multiport valve 42 may be an external element, preceding the fluid inlet 22 of the sensor carrier 12, as shown in Fig. 6 , or it can be an integral element of the sensor carrier 12.
- a device e.g. a reactor for testing catalyst arrays, the waste-gas of which is to be analyzed.
- the inventive device 10 is therein arranged below the test reactor 44, wherein the waste-gas apertures of the test reactor 44 are congruent with the fluid inlet apertures 22 of the inventive device 10.
- the waste gas 48 is, at least in this embodiment, is conducted only to one microsensor 14 in the sensor carrier 12, originating from an e.g. catalyst 46 to be tested.
- the waste-gas flow 48 may also be conducted individually, e.g. in using a multiport valve 42 via the whole sensor device, in particular if various microsensors 14 are provided within an array for analyzing various reaction products of a waste-gas flow.
- the sensor carriers 12, described in the previous figures, can also be used instead of or in combination with the sensor carrier device shown in figure 7 .
- the inventive device 10 can be further spaced (spatially separated) from the test reactor 44 wherein appropriate connection elements for conducting the fluid medium to be analyze are then to be provided, which may in turn be heatable.
- Fig. 8 shows the principle construction of a microsensor 14 wherein the sensor material is applied onto a ring-shaped carrier in the form of a gradient.
- the carrier can therein be coated on top or bottom with preferably various concentrations of sensor materials.
- the ring-shaped carrier of this embodiment is preferably porous.
- 94 various sensor materials for microsensors, or being microsensors themselves, were synthesized.
- Table 1 shows the composition of each individual sensor material. All were produced by means of impregnating of Al 2 O 3 bodies. Therein, the following aqueous metal salt solutions were used:
- Fig. 9 shows the occupancy of the sensor device with the individual microsensors.
- the positions B1 and E7 contain pure Al 2 O 3 materials in order to generate reference positions for no sensor activity whatsoever (blind values).
- An IR camera of the type AIM/Aegais PtSi 256x256 is calibrated to the temperature of the sensor device via an emissivity correction (as per WO 99/34206 ) so that even small differences of temperature in the sensor activity can be detected with high resolution.
- Fig. 10 shows the result of 0.2 ml/min acetone in 800 ml/min N 2 .
- a characteristic pattern is created over the 96 sensor positions A1-H12, wherein the most microsensors on iridium basis show heat emission when contacted with acetone in the rows 1 - 4.
- the gray scale values on the right side of Fig. 10 show the intensity of heat toning coded in gray values. It has to be taken into account that the scale ranges from dark to light back to dark, that, e.g., the heat emission on position D4 increases in the middle of the microsensors, and does not decrease.
- Fig. 11 a and 11b show the analogous experiment with two different concentrations of cyclohexane, wherein Fig. 11b shows the analogous experiment conditions to Fig. 10 , merely the organic molecule is different. A completely different intensity and response pattern of the microsensors is clearly recognizable. Cyclohexane causes in the rows 5 to 12 merely sensor activity at the column A as well as the position B10. In Fig. 10 (acetone), large areas are ? (rows 7-12). In the same way, the doubling of the concentration of cyclohexane ( Fig. 11a and 11b ) in the gas flow doubles the intensities of the heat emission via corresponding materials.
- Fig. 12 shows the results for 3 different methanol concentrations within the gas flow, besides a completely new pattern, the dependency of the intensity of the heat tonings from the concentration of the fluid in the gas phase is recognizable again.
- Fig. 13 shows the results when streaming an aromatic aldehyde. Therein, three different concentrations of benzaldehyde are dosed into the gas flow.
- Fig. 14 shows the result when streaming an acetone/methanol mixture.
- the device After calibration of the arrangement, it is thus easily possible to identify substances in mixtures according to their "pattern” or "fingerprint” on the sensor device.
- This pattern recognition for qualitative detective can also be automated via a software (comparisons via a large library).
- the device is first calibrated with various concentrations of substances or substance mixtures, the determination of the contents is the performed via the evaluation the intensity of the whole pattern or the intensity of at least one characteristic microsensor or sensor material for this substance or for the mixture.
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Claims (16)
- Procédé pour l'analyse d'un milieu fluide dans lequel le milieu fluide est guidé par-dessus au moins deux micro-capteurs (14) d'un assemblage de capteurs, comprenant au moins deux micro-capteurs (14) ayant la propriété d'être différents, et dans lequel les au moins deux micro-capteurs (14) sont thermographiquement contrôlés au moyen d'au moins un détecteur en ce qui concerne un changement de propriétés, où le changement de propriétés des au moins deux micro-capteurs (14) est spécifique pour au moins un composant prédéterminé du milieu fluide, caractérisé en ce que l'évaluation est effectuée selon une reconnaissance de motif de telle manière que les valeurs de mesure détectées sont comparées avec des banques de données de motifs et que, à partir de là, de préférence automatiquement, l'identité et la quantité de l'au moins un composant dans le milieu fluide sont déterminées.
- Procédé selon la revendication 1, dans lequel le transfert de signal à partir des au moins deux micro-capteurs (14) à destination de l'au moins un détecteur est effectué sans aucune connexion à conduction électrique, en particulier sans fil.
- Procédé selon la revendication 1 ou 2, dans lequel l'au moins un détecteur est une caméra infrarouge (26) ou un ensemble de diodes infrarouges ou une diode infrarouge traversable.
- Procédé selon l'une quelconque des revendications précédentes dans lequel le changement de propriétés est choisi parmi les possibilités suivantes : effet thermoélectrique, effet Peltier, effet Chelat, adsorption telle que chimisorption et physisorption, désorption, réactions catalytiques, formation de complexes, reconnaissance moléculaire.
- Procédé selon l'une quelconque des revendications 1 à 4 destiné à la détection de drogues, d'échantillons, d'explosifs, de moyens de combat, de pesticides, de poisons écologiques ; à des applications dans le contrôle de processus, le contrôle de qualité dans la nourriture, l'alimentation animale et l'industrie cosmétique, dans le domaine de la criminalistique (expertise médicolégale), dans la collecte de preuves ; à une analyse chimique avec ou sans association à des procédés d'analyse déjà connus ; à des essais olfactifs dans l'industrie des biens de consommation courante ; à la détection de ressources minérales ; à la recherche extraterrestre.
- Dispositif (10) pour exécuter le procédé selon l'une quelconque des revendications 1 à 4, comprenant :1) des moyens pour recevoir au moins deux micro-capteurs (14) individuels avec ou sans porte-capteur (12) avec au moins deux sections (36) différentes, séparés l'un de l'autre, pour constituer un assemblage de capteurs,2) des moyens pour guider au sein et en dehors d'au moins un milieu fluide au moins une section (36) du dispositif de détection avec une mise en contact simultanée du milieu fluide avec au moins deux micro-capteurs (14),3) au moins un détecteur pour déterminer de façon thermographique au moins un changement de propriétés des micro-capteurs (14), et4) un équipement de traitement de données (30) qui traite les sections (36) détectées lors d'une mesure d'au moins un changement de propriétés avec les valeurs de mesure correspondantes selon leur position au sein du porte-capteur (12), caractérisé en ce que l'équipement de traitement de données est programmé pour évaluer les valeurs de mesure selon une reconnaissance de motif, de telle manière que les valeurs sont comparées avec les banques de données de motifs et qu'à partir de là, l'identité et la quantité d'au moins un composant du fluide sont déterminées.
- Dispositif (10) selon la revendication 6 caractérisé en ce que les moyens de réception des au moins deux micro-capteurs (14) individuels et/ou des au moins deux micro-capteurs (14) individuels sont arbitrairement interchangeables.
- Dispositif (10) selon l'une des revendications 6 ou 7, comprenant en outre un boîtier (20) où le porte-capteur (12) est ménagé.
- Dispositif (10) selon l'une quelconque des revendications 6 à 8, dans lequel le dispositif (10) comprend un moyen de chauffage (18) et/ou un moyen de réfrigération du boîtier (20) et/ou du porte-capteur (12).
- Dispositif (10) selon l'une quelconque des revendications 8 ou 9, caractérisé en ce que le boîtier (20) comporte une fenêtre perméable aux infrarouges (16) et que le détecteur infrarouge est ménagé à l'extérieur du boîtier (20) en face de la fenêtre perméable aux infrarouges (16).
- Dispositif (10) selon l'une quelconque des revendications 8 à 10 caractérisé en ce que le boîtier (20) et/ou le porte-capteur (12) sont constitués complètement ou partiellement de silicium et/ou de saphir ou d'un autre matériau approprié, perméable aux infrarouges, ou d'ardoise.
- Dispositif (10) selon l'une quelconque des revendications 8 à 11 caractérisé en ce que les moyens de guidage au sein et en dehors d'au moins un milieu fluide comprennent des canaux (34) au sein du porte-capteur (12).
- Dispositif (10) selon la revendication 12, caractérisé en ce que les canaux (34) connectent plus d'une section l'une avec l'autre (36).
- Dispositif (10) selon l'une quelconque des revendications 8 à 13 comprenant en outre au moins un robinet multivoies (42) et/ou un dispositif permettant une distribution égale du milieu fluide dans la totalité d'au moins une section de l'ensemble de capteur.
- Dispositif selon l'une quelconque des revendications 6 à 14 dans lequel la composition des micro-capteurs (14) change de manière continue ou discontinue.
- Utilisation du procédé ou du dispositif (10) selon l'une quelconque des revendications précédentes pour contrôler des conversions chimiques.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10143517 | 2001-09-05 | ||
DE10143517A DE10143517A1 (de) | 2001-09-05 | 2001-09-05 | Verfahren und Vorrichtung zur Analyse eines fluiden Mediums |
PCT/EP2002/009951 WO2003023386A1 (fr) | 2001-09-05 | 2002-09-05 | Procede et dispositif pour l'analyse de milieu liquide |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1423684A1 EP1423684A1 (fr) | 2004-06-02 |
EP1423684B1 true EP1423684B1 (fr) | 2008-08-27 |
Family
ID=7697808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02777005A Expired - Fee Related EP1423684B1 (fr) | 2001-09-05 | 2002-09-05 | Procede et dispositif pour l'analyse de milieu liquide |
Country Status (4)
Country | Link |
---|---|
US (1) | US20040248315A1 (fr) |
EP (1) | EP1423684B1 (fr) |
DE (2) | DE10143517A1 (fr) |
WO (1) | WO2003023386A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6966693B2 (en) * | 2003-01-14 | 2005-11-22 | Hewlett-Packard Development Company, L.P. | Thermal characterization chip |
JP4065528B2 (ja) * | 2003-03-10 | 2008-03-26 | キヤノン株式会社 | 恒温真空容器及びそれを用いた露光装置 |
US7545272B2 (en) | 2005-02-08 | 2009-06-09 | Therasense, Inc. | RF tag on test strips, test strip vials and boxes |
US9538657B2 (en) | 2012-06-29 | 2017-01-03 | General Electric Company | Resonant sensor and an associated sensing method |
US9589686B2 (en) | 2006-11-16 | 2017-03-07 | General Electric Company | Apparatus for detecting contaminants in a liquid and a system for use thereof |
US9658178B2 (en) | 2012-09-28 | 2017-05-23 | General Electric Company | Sensor systems for measuring an interface level in a multi-phase fluid composition |
US10914698B2 (en) | 2006-11-16 | 2021-02-09 | General Electric Company | Sensing method and system |
US9536122B2 (en) | 2014-11-04 | 2017-01-03 | General Electric Company | Disposable multivariable sensing devices having radio frequency based sensors |
US9195925B2 (en) * | 2012-07-26 | 2015-11-24 | General Electric Company | Method and system for improved wireless sensing |
US20100311109A1 (en) * | 2009-06-03 | 2010-12-09 | Salaimeh Ahmad A | Non-contact method for quantifying changes in the dynamics of microbial populations |
EP2335861B1 (fr) * | 2009-12-21 | 2013-02-13 | C.R.F. Società Consortile per Azioni | Procédé et appareil pour unir les panneaux constituant les composants des carrosseries de véhicules à moteur, avec contrôle qualité au travers d'une détection thermographique de l'ensemble des bords pérîphériques |
US8542023B2 (en) | 2010-11-09 | 2013-09-24 | General Electric Company | Highly selective chemical and biological sensors |
US9746452B2 (en) | 2012-08-22 | 2017-08-29 | General Electric Company | Wireless system and method for measuring an operative condition of a machine |
US10598650B2 (en) | 2012-08-22 | 2020-03-24 | General Electric Company | System and method for measuring an operative condition of a machine |
US10684268B2 (en) | 2012-09-28 | 2020-06-16 | Bl Technologies, Inc. | Sensor systems for measuring an interface level in a multi-phase fluid composition |
ES2579655B1 (es) * | 2015-02-12 | 2017-06-01 | Universidad De Salamanca | Equipo portátil de puntería para cámaras termográficas |
CN105403591A (zh) * | 2015-11-11 | 2016-03-16 | 无锡市路华肥料科技有限公司 | 肥料检测装置 |
DE102017128566A1 (de) | 2017-12-01 | 2019-06-06 | Endress+Hauser Flowtec Ag | Sensoranordnung zur Anordnung an einer Prozessanlage, sowie Verfahren zum Betrieb der Sensoranordnung und Prozessanlage |
WO2023198804A1 (fr) | 2022-04-14 | 2023-10-19 | Hte Gmbh The High Throughput Experimentation Company | Dispositif de traitement thermique |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1556339A (en) * | 1977-08-25 | 1979-11-21 | English Electric Valve Co Ltd | Combustible gas detectors |
DE3519397A1 (de) * | 1985-05-30 | 1986-12-04 | Siemens AG, 1000 Berlin und 8000 München | Sensor fuer gasanalyse bzw. -detektion |
GB8617429D0 (en) * | 1986-07-17 | 1986-08-28 | Atomic Energy Authority Uk | Sensing |
US4874500A (en) * | 1987-07-15 | 1989-10-17 | Sri International | Microelectrochemical sensor and sensor array |
US5345213A (en) * | 1992-10-26 | 1994-09-06 | The United States Of America, As Represented By The Secretary Of Commerce | Temperature-controlled, micromachined arrays for chemical sensor fabrication and operation |
FR2710153B1 (fr) * | 1993-09-17 | 1995-12-01 | Alpha Mos Sa | Procédés et appareils de détection des substances odorantes et applications. |
US5788833A (en) * | 1995-03-27 | 1998-08-04 | California Institute Of Technology | Sensors for detecting analytes in fluids |
EP0791824A2 (fr) * | 1996-02-21 | 1997-08-27 | Osaka Gas Co., Ltd. | Méthode de fabrication d'un détecteur d'oxyde de nitrogène, détecteur d'oxyde de nitrogène fabriqué par cette méthode et du matériel pour celle-là |
US6063633A (en) * | 1996-02-28 | 2000-05-16 | The University Of Houston | Catalyst testing process and apparatus |
EP0851222A1 (fr) * | 1996-12-31 | 1998-07-01 | Corning Incorporated | Detecteur d'hydrocarbures à base de métal-oxyde-semiconducteur catalytique |
US5945343A (en) * | 1997-08-05 | 1999-08-31 | Bayer Corporation | Fluorescent polymeric sensor for the detection of urea |
JP2002500359A (ja) * | 1997-12-23 | 2002-01-08 | ハーテーエー・アクチェンゲゼルシャフト | 熱ディファレンス・イメージを用いる物質の組合せ開発のための方法 |
DE60023005T2 (de) * | 1999-06-17 | 2006-07-20 | Smiths Detection Inc., Pasadena | Vielfach-sensor-system und -gerät |
US6602714B1 (en) * | 1999-11-09 | 2003-08-05 | Sri International | Viscosity and mass sensor for the high-throughput synthesis, screening and characterization of combinatorial libraries |
-
2001
- 2001-09-05 DE DE10143517A patent/DE10143517A1/de not_active Withdrawn
-
2002
- 2002-09-05 EP EP02777005A patent/EP1423684B1/fr not_active Expired - Fee Related
- 2002-09-05 DE DE60228590T patent/DE60228590D1/de not_active Expired - Fee Related
- 2002-09-05 WO PCT/EP2002/009951 patent/WO2003023386A1/fr active IP Right Grant
- 2002-09-05 US US10/488,566 patent/US20040248315A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003023386A1 (fr) | 2003-03-20 |
US20040248315A1 (en) | 2004-12-09 |
DE10143517A1 (de) | 2003-03-27 |
EP1423684A1 (fr) | 2004-06-02 |
DE60228590D1 (de) | 2008-10-09 |
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