EP1420808A4 - Treatment of tuberculosis using immunomodulator compounds - Google Patents

Treatment of tuberculosis using immunomodulator compounds

Info

Publication number
EP1420808A4
EP1420808A4 EP01271057A EP01271057A EP1420808A4 EP 1420808 A4 EP1420808 A4 EP 1420808A4 EP 01271057 A EP01271057 A EP 01271057A EP 01271057 A EP01271057 A EP 01271057A EP 1420808 A4 EP1420808 A4 EP 1420808A4
Authority
EP
European Patent Office
Prior art keywords
tuberculosis
treatment
immunomodulator compounds
immunomodulator
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01271057A
Other languages
German (de)
French (fr)
Other versions
EP1420808A1 (en
Inventor
Alexander A Kolobov
Andrey S Simbirtsev
Tat Yana I Vinogradova
Natal Ya V Zabolotnyh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sciclone Pharmaceuticals LLC
Original Assignee
Sciclone Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sciclone Pharmaceuticals LLC filed Critical Sciclone Pharmaceuticals LLC
Priority to EP09000806A priority Critical patent/EP2078525A3/en
Publication of EP1420808A1 publication Critical patent/EP1420808A1/en
Publication of EP1420808A4 publication Critical patent/EP1420808A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
EP01271057A 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds Withdrawn EP1420808A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09000806A EP2078525A3 (en) 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2001115900/14A RU2229892C2 (en) 2001-06-08 2001-06-08 Method for treatment of pulmonary tuberculosis
RU2001115900 2001-08-06
PCT/US2001/048560 WO2003013572A1 (en) 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP09000806A Division EP2078525A3 (en) 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds

Publications (2)

Publication Number Publication Date
EP1420808A1 EP1420808A1 (en) 2004-05-26
EP1420808A4 true EP1420808A4 (en) 2006-06-07

Family

ID=20250617

Family Applications (2)

Application Number Title Priority Date Filing Date
EP01271057A Withdrawn EP1420808A4 (en) 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds
EP09000806A Withdrawn EP2078525A3 (en) 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP09000806A Withdrawn EP2078525A3 (en) 2001-06-08 2001-12-20 Treatment of tuberculosis using immunomodulator compounds

Country Status (4)

Country Link
EP (2) EP1420808A4 (en)
JP (1) JP4837251B2 (en)
RU (1) RU2229892C2 (en)
WO (1) WO2003013572A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ551457A (en) * 2004-05-14 2009-12-24 Sciclone Pharmaceuticals Inc Treatment or prevention of respiratory viral infections with immunomodulator compounds
US20090074815A1 (en) * 2005-04-22 2009-03-19 Sciclone Pharmaceuticals, Inc. Immunomodulator Compounds as Vaccine Enhancers
CA2677749A1 (en) 2007-02-13 2008-08-21 Sciclone Pharmaceuticals, Inc. Method of treating or preventing tissue deterioration, injury or damage due to disease of mucosa
JP2010536854A (en) * 2007-08-23 2010-12-02 サイクローン・ファーマシューティカルズ・インコーポレイテッド Lung cancer treatment
RU2450820C2 (en) * 2010-07-20 2012-05-20 Государственное учреждение "Научно-практический центр "Фтизиатрия" Министерства здравоохранения республики Саха (Якутия) Method of treating destructive pulmonary tuberculosis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020063A2 (en) * 1993-03-04 1994-09-15 Cytoven International N.V. Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
WO1997019691A1 (en) * 1995-11-28 1997-06-05 Wei, Edward, T. Gamma-l-glutamyl containing immunomodulator compounds and methods therewith
US5916878A (en) * 1995-11-28 1999-06-29 Edward T. Wei γ-glutamyl and β-aspartyl containing immunomodulator compounds and methods therewith
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520196A (en) * 1983-08-18 1985-05-28 American Home Products Corporation α-Mercaptophenylacetic acid derivatives of imidazole-containing compounds and analogues thereof
US5212192A (en) * 1989-11-24 1993-05-18 Janssen Pharmaceutica N.V. Immunostimulating 6-aryl-5,6-dihydroimidazo[2,1-b]thiazole derivatives
ES2174124T3 (en) * 1995-12-14 2002-11-01 Novelos Therapeutics Inc GLUTATION OXIDIZED AS AN INCREASER OF THE ENDOGENOUS PRODUCTION OF CYTOKINES AND HEMATOPOYETIC FACTORS.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020063A2 (en) * 1993-03-04 1994-09-15 Cytoven International N.V. Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
WO1997019691A1 (en) * 1995-11-28 1997-06-05 Wei, Edward, T. Gamma-l-glutamyl containing immunomodulator compounds and methods therewith
US5916878A (en) * 1995-11-28 1999-06-29 Edward T. Wei γ-glutamyl and β-aspartyl containing immunomodulator compounds and methods therewith
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BIOCENTURY, 8(10, PT. 2), P. B13. ISSN: 1097-7201; CODEN: BICEFS., 28 February 2000 (2000-02-28) *
BUCHAN G.S. ET AL: "Tuberculosis in domesticated deer cervus-elaphus a large anumal model for tuberculosis", JOURNAL OF COMPARATIVE PATHOLOGY, vol. 103, no. 1, 1990, pages 11 - 22 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1990, Database accession no. PREV199090100455 *
DATABASE CIN [online] "Other Research News", XP002377620, retrieved from STN Database accession no. 29(11):11078F *
DATABASE IMSDRUGNEWS [online] R & D Focus Drug News; 22 January 2001 (2001-01-22), XP002377621, retrieved from STN Database accession no. AN = 2001:333 *
DATABASE IMSDRUGNEWS [online] R & D Focus Drug News; 6 September 1999 (1999-09-06), XP002377619, retrieved from STN Database accession no. 1999:2565 *
NICOLAUS B.J.R.: "symbiotic approach to drug design", DECISION MAKING IN DRUG RESEARCH, 1983, pages 173 - 186, XP002197412 *
See also references of WO03013572A1 *

Also Published As

Publication number Publication date
RU2229892C2 (en) 2004-06-10
EP1420808A1 (en) 2004-05-26
JP2004537579A (en) 2004-12-16
EP2078525A3 (en) 2010-09-08
WO2003013572A1 (en) 2003-02-20
EP2078525A2 (en) 2009-07-15
JP4837251B2 (en) 2011-12-14

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